Search Results (3)

A sustainable, alternative weed control strategy is developed using salicylaldehyde (SA; 2-hydroxybenzaldehyde) as an active ingredient. SA is a natural, redox-active small molecule listed as a Generally Recognized As Safe food additive by the European Food Safety Authority and the United States Food and Drug Administration. The repurposing of SA determined that SA possesses both pre- and post-emergent herbicidal, fumigant activity, where the emitted SA from the source completely prevented the germination of plant seeds and/or the growth of the germinated plants. As a proof-of-concept, we developed agricultural byproducts (tree nutshell particles) as SA delivery vehicles to the soil, thus helping the growers’ sustainable byproduct recycling program, necessary for carbon sequestration. In plate assays, SA emitted from the nutshell vehicles (0.15 to 1.6 M) completely prevented the germination of six invasive or native weed seeds (monocots, dicots). In Magenta vessel assays, SA emitted from the nutshell vehicles (0.8 to 1.6 M) not only prevented the germination (pre-emergent) of Lagurus ovatus (Bunny Tails Grass) seeds but also inhibited the growth (post-emergent) of the germinated weeds. We determined further that soil covering (soil pasteurization) could be one of the practices to effectively deliver SA to the soil, whereby 1.6 M of SA emitted from the nutshell vehicles prevented the germination of the L. ovatus seeds maintained in soil trays covered with plastic tarp at 22 °C, while 0.8 M SA allowed partial (15%) germination of the weed seeds. Of note, SA also possesses an intrinsic antifungal activity that overcomes the tolerance of the stress signaling mutants of filamentous fungal pathogens (Aspergillus fumigatus, Penicillium expansum) to the phenylpyrrole fungicide fludioxonil. Environmental degradation data available in the public database indicate that, once released to the environment, SA will be broken down in the air by sunlight or microorganisms and, thus, is not built up in aquatic organisms. Altogether, SA can serve as a safe, potent pesticide (herbicidal, fungicidal) ingredient that promotes sustainable crop production by lowering the pesticide burden in fields. Full article

Understanding the impacts of environmental factors on spatial–temporal and large-scale rodent distribution is important for rodent damage prevention. Investigating rat hole density (RHD) is one of the most effective methods to obtain the intensity of rodent damage. However, most of the previous field surveys or UAV-based remote sensing methods can only evaluate small-scale RHD and its influencing factors. However, these studies did not consider large-scale temporal and spatial heterogeneity. Therefore, we collected small-scale and in situ measurement records of RHD on the northern slope of the Tien Shan Mountains in Xinjiang (NTXJ), China, from 1982 to 2015, and then used correlation analysis and Bayesian network (BN) to analyze the environmental impacts on large-scale RHD with satellite remote sensing data such as the GIMMS NDVI product. The results show that the built BN can better quantify causality in the environmental mechanism modeling of RHD. The NDVI and LAI data from satellite remote sensing are important to the spatial–temporal RHD distribution and the mapping in the future. In regions with an elevation higher than 600 m (UPR) and lower than 600 m (LWR) of NTXJ, there are significant differences in the driving mechanism patterns of RHD, which are dependent on the elevation variation. In LWR, vegetation conditions have a weaker impact on RHD than UPR. It is possibly due to the Artemisia eaten by the dominant species Lagurus luteus (LL) in UPR being more sensitive to precipitation and temperature if compared with the Haloxylon ammodendron eaten by the Rhombomys opimus (RO) in LWR. In LWR, grazing intensity is more strongly and positively correlated to RHD than UPR, possibly due to both winter grazing and RO dependency on vegetation distribution; moreover, in UPR, sheep do not feed Artemisia as the main food, and the total vegetation is sufficient for sheep and LL to coexist. Under the different conditions of water availability of LWR and UPR, grazing may affect the ratio of aboveground and underground biomass by photosynthate allocation, thereby affecting the distribution of RHD. In extremely dry years, the RHD of LWR and UPR may have an indirect interactive relation due to changes in grazing systems. Full article

The clinical manifestation of leishmaniases depends on parasite species, host genetic background, and immune response. Manifestations of human leishmaniases are highly variable, ranging from self-healing skin lesions to fatal visceral disease. The scope of standard model hosts is insufficient to mimic well the wide disease spectrum, which compels the introduction of new model animals for leishmaniasis research. In this article, we study the susceptibility of three Asian rodent species (Cricetulus griseus, Lagurus lagurus, and Phodopus sungorus) to Leishmania major and L. donovani. The external manifestation of the disease, distribution, as well as load of parasites and infectiousness to natural sand fly vectors, were compared with standard models, BALB/c mice and Mesocricetus auratus. No significant differences were found in disease outcomes in animals inoculated with sand fly- or culture-derived parasites. All Asian rodent species were highly susceptible to L. major. Phodopus sungorus showed the non-healing phenotype with the progressive growth of ulcerative lesions and massive parasite loads. Lagurus lagurus and C. griseus represented the healing phenotype, the latter with high infectiousness to vectors, mimicking best the character of natural reservoir hosts. Both, L. lagurus and C. griseus were also highly susceptible to L. donovani, having wider parasite distribution and higher parasite loads and infectiousness than standard model animals. Full article