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32 Results Found

  • Article
  • Open Access
4 Citations
3,605 Views
15 Pages

10 October 2023

Infectious bovine rhinotracheitis (IBR) caused by bovine herpes virus 1 (BoHV-1) can lead to enormous economic losses in the cattle industry. Vaccine immunization is preferentially used to decrease its transmission speed and resultant clinical signs,...

  • Article
  • Open Access
1 Citations
1,467 Views
13 Pages

The Influence of the Associated Inactivated Vaccine Against Infectious Rhinotracheitis and Bovine Viral Diarrhea on the Formation and Duration of Colostral Immunity in Kazakh Whiteheaded Calves

  • Yerbol Bulatov,
  • Alina Kurmasheva,
  • Zhanat Amanova,
  • Ruslan Abitaev,
  • Zhanna Sametova,
  • Asselya Kyrgyzbayeva,
  • Zhanat Kondybaeva,
  • Sholpan Turyskeldi,
  • Abdurakhman Ussembay and
  • Dariya Toktyrova
  • + 7 authors

15 April 2025

Objectives: This article presents a study evaluating the antibody levels against infectious bovine rhinotracheitis (IBR) and bovine viral diarrhea (BVD) in Kazakh Whiteheaded calves born to dams immunized with an experimental inactivated combined vac...

  • Brief Report
  • Open Access
563 Views
8 Pages

A Simple Deterministic Model of Protection and Cost Benefits from Vaccinating Indian Cattle Against Infectious Bovine Rhinotracheitis

  • Bhaskar Ganguly,
  • Sarvesh Tayshete,
  • Priyabrata Pattnaik,
  • Nyayapati Sunil Narayana Bhargav and
  • Anand Kumar Kanakasapapathy

22 September 2025

Infectious Bovine Rhinotracheitis (IBR) is endemic in India, causing significant losses to dairy enterprises. Until recently, the unavailability of an indigenously manufactured vaccine and the high cost of imported vaccines limited national vaccinati...

  • Article
  • Open Access
2 Citations
1,013 Views
18 Pages

An Open-Label, Randomized Field Trial Demonstrates Safety and Immunogenicity of Inactivated gE-Deleted Marker Vaccine Against Infectious Bovine Rhinotracheitis in Cattle

  • Bhaskar Ganguly,
  • Sarvesh Tayshete,
  • Deepa Padinjare Melepat,
  • Sudhakar Awandkar,
  • Srinivas Karnati,
  • Priyabrata Pattnaik and
  • Anand Kumar Kanakasapapathy

Background: Infectious Bovine Rhinotracheitis (IBR), Infectious Pustular Balanoposthitis (IPB), Infectious Pustular Vulvovaginitis (IPV), late-term abortions, and neurological and systemic disease are common manifestations of Bovine Herpesvirus-1 (Bo...

  • Article
  • Open Access
1 Citations
959 Views
21 Pages

24 September 2025

Background/Objectives: A new multivalent vaccine (DIVENCE® PENTA), containing Bovine viral diarrhoea virus (BVDV) types 1 and 2 recombinant proteins, live gE/tk double gene deleted Bovine Herpesvirus type 1 (BoHV-1 or IBR), live attenuated Bovine...

  • Article
  • Open Access
15 Citations
3,511 Views
12 Pages

Assessment of Different Infectious Bovine Rhinotracheitis Marker Vaccines in Calves

  • Stefano Petrini,
  • Alessandra Martucciello,
  • Cecilia Righi,
  • Giovanna Cappelli,
  • Claudia Torresi,
  • Carlo Grassi,
  • Eleonora Scoccia,
  • Giulia Costantino,
  • Cristina Casciari and
  • Roberto Sabato
  • + 3 authors

28 July 2022

Three commercially available infectious bovine rhinotracheitis (IBR) live marker vaccines were evaluated for their ability to provide clinical protection to vaccinated calves against wild-type (wt) Bovine alphaherpesvirus-1 (BoHV-1) challenge and the...

  • Article
  • Open Access
11 Citations
3,830 Views
20 Pages

Application of Methods to Assess Animal Welfare and Suffering Caused by Infectious Diseases in Cattle and Swine Populations

  • Søren Saxmose Nielsen,
  • Hans Houe,
  • Matthew Denwood,
  • Liza Rosenbaum Nielsen,
  • Björn Forkman,
  • Nina Dam Otten and
  • Jens Frederik Agger

20 October 2021

Control of infectious diseases in livestock has often been motivated by food safety concerns and the economic impact on livestock production. However, diseases may also affect animal welfare. We present an approach to quantify the effect of five infe...

  • Communication
  • Open Access
5 Citations
2,297 Views
8 Pages

13 November 2023

Bovine alphaherpesviruses, BoAHV, can cause respiratory, genital and neurological disorders. In particular, bovine alphaherpesvirus type 1 (BoAHV1) is one of the most significant ruminant pathogens worldwide and it can heavily damage the livestock in...

  • Article
  • Open Access
7 Citations
7,178 Views
8 Pages

Serosurvey for Infectious Agents Associated with Subfertility and Abortion in Dairy Cattle in Trinidad and Tobago, West Indies

  • Michael J. Morris,
  • Jamie Sookhoo,
  • Lemar Blake,
  • Arianne Brown Jordan,
  • Justine John,
  • Sheliza Ali,
  • Gervaise Sarjusingh,
  • Janelle St. Aime,
  • Edward H. Amoroso and
  • Christopher A. L. Oura

Despite frequent reports of subfertility and abortion in dairy cattle in Trinidad and Tobago (T&T), little is known about the potential infectious and non-infectious causes. This study set out to investigate possible infectious causes of reproduc...

  • Communication
  • Open Access
4 Citations
2,048 Views
11 Pages

A Qualitative PCR Assay for the Discrimination of Bubaline Herpesvirus 1, Bovine Herpesvirus 1 and Bovine Herpesvirus 5

  • Francesca Oberto,
  • Emanuele Carella,
  • Claudio Caruso,
  • Pier Luigi Acutis,
  • Davide Lelli,
  • Luigi Bertolotti,
  • Loretta Masoero and
  • Simone Peletto

Bubaline herpesvirus 1 (BuHV-1), Bovine herpesvirus 1 (BoHV-1) and Bovine herpesvirus 5 (BoHV-5) are classified in the genus Varicellovirus, subfamily Alphaherpesvirinae. BoHV-1 is the causative agent of infectious bovine rhinotracheitis, BoHV-5 indu...

  • Article
  • Open Access
4 Citations
2,347 Views
12 Pages

Assessment of BoAHV-1 Seronegative Latent Carrier by the Administration of Two Infectious Bovine Rhinotracheitis Live Marker Vaccines in Calves

  • Stefano Petrini,
  • Cecilia Righi,
  • Giulia Costantino,
  • Eleonora Scoccia,
  • Paola Gobbi,
  • Claudia Pellegrini,
  • Michela Pela,
  • Monica Giammarioli,
  • Giulio Viola and
  • Roberto Sabato
  • + 2 authors

3 February 2024

Seronegative latent carriers (SNLCs) are animals that carry the virus without detectable antibodies and pose a risk for disease transmission and diagnostic challenges, suggesting the importance of consideration of marker vaccines in managing them. Th...

  • Article
  • Open Access
20 Citations
4,982 Views
10 Pages

Evaluation of Passive Immunity Induced by Immunisation Using Two Inactivated gE-deleted Marker Vaccines against Infectious Bovine Rhinotracheitis (IBR) in Calves

  • Stefano Petrini,
  • Cecilia Righi,
  • Carmen Iscaro,
  • Giulio Viola,
  • Paola Gobbi,
  • Eleonora Scoccia,
  • Elisabetta Rossi,
  • Claudia Pellegrini and
  • Gian Mario De Mia

4 January 2020

Different types of vaccines against Infectious Bovine Rhinotracheitis (IBR) are commercially available. Among these, inactivated glycoprotein E (gE)-deleted marker vaccines are commonly used, but their ability to induce passive immunity is poorly kno...

  • Article
  • Open Access
4 Citations
2,604 Views
11 Pages

Impact of Overuse and Sexually Transmitted Infections on Seminal Parameters of Extensively Managed Bulls

  • Giovanni Montoya-Monsalve,
  • María-Jesús Sánchez-Calabuig,
  • Javier Blanco-Murcia,
  • Laura Elvira,
  • Alfonso Gutiérrez-Adán and
  • Priscila Ramos-Ibeas

15 March 2021

Natural service remains the main breeding method in extensively managed beef herds. Although the bull might be the most important factor in determining herd fertility, its importance has been largely overlooked, focusing instead on female fertility....

  • Review
  • Open Access
1 Citations
2,529 Views
20 Pages

Regulation (EU) 2016/429 introduces comprehensive guidelines for managing transmissible animal diseases, including zoonoses. The subsequent Commission Implementing Regulation 2018/1882 categorizes these diseases into five groups, each with specific r...

  • Article
  • Open Access
3 Citations
2,043 Views
19 Pages

Investigation of Comorbidity and Risk Factors Analysis During Lumpy Skin Disease Outbreaks in India

  • Gundallahalli Bayyappa Manjunatha Reddy,
  • Shraddha Bijalwan,
  • Siju Susan Jacob,
  • Sunil Tadakod,
  • Snigdha Madhaba Maharana,
  • Sudeep Nagaraj,
  • Sai Mounica Pabbineedi,
  • Chandana Ramesh Uma,
  • Viveka Prabhu Balappa and
  • Chethan Kumar Harlipura Basavarajappa
  • + 3 authors

Lumpy skin disease (LSD) is a re-emerging viral transboundary disease affecting cattle and buffaloes, resulting in a significant socio-economic impact on the affected regions. LSD is primarily transmitted among susceptible livestock through hematopha...

  • Article
  • Open Access
15 Citations
4,166 Views
11 Pages

Field Evaluation of Commercial Vaccines against Infectious Bovine Rhinotracheitis (Ibr) Virus Using Different Immunization Protocols

  • Laureana De Brun,
  • Mauro Leites,
  • Agustín Furtado,
  • Fabricio Campos,
  • Paulo Roehe and
  • Rodrigo Puentes

20 April 2021

Bovine alphaherpesvirus 1 is ubiquitous in cattle populations and is associated with several clinical syndromes, including respiratory disease, genital disease, infertility and abortions. Control of the virus in many parts of the world is achieved pr...

  • Article
  • Open Access
5 Citations
3,476 Views
14 Pages

Genomic Association between SNP Markers and Diseases in the “Curraleiro Pé-Duro” Cattle

  • Thais Miranda Silva Freitas,
  • Juliana Moraes Dias,
  • Luanna Kim Pires Guimarães,
  • Sáudio Vieira Peixoto,
  • Rayanne Henrique Santana da Silva,
  • Kareem Rady Badr,
  • Maria Ivete Moura,
  • Adriana Santana do Carmo,
  • Vincenzo Landi and
  • Maria Clorinda Soares Fioravanti

25 May 2021

Susceptibility to diseases is inherited and can be transmitted between populations. Single-nucleotide polymorphism (SNPs) in genes related to immune response is associated with diseases in cattle. This study investigated SNPs in the genomic region of...

  • Communication
  • Open Access
1,898 Views
14 Pages

Isolation of the Initial Bovine Alphaherpesvirus 1 Isolate from Yanbian, China

  • Jingrui Hao,
  • Jingfeng Fu,
  • Kai Yu,
  • Xu Gao,
  • Keyan Zang,
  • Haoyuan Ma,
  • Haowen Xue,
  • Yanhao Song,
  • Kunru Zhu and
  • Meng Yang
  • + 1 author

1 August 2024

Bovine infectious rhinotracheitis (IBR), caused by bovine alphaherpesvirus 1 (BoAHV1), poses significant challenges to the global cattle industry due to its high contagiousness and economic impact. In our study, we successfully isolated a BoAHV1 stra...

  • Article
  • Open Access
2 Citations
1,500 Views
10 Pages

24 November 2024

Background: Bovine respiratory syncytial virus (BRSV) is a significant cause of bovine respiratory disease, resulting in significant losses to the cattle industry. For rapid detection of BRSV, a real-time recombinase-aided isothermal amplification as...

  • Article
  • Open Access
4 Citations
2,090 Views
11 Pages

Humoral Immune Response of Mice against a Vaccine Candidate Composed of a Chimera of gB of Bovine Alphaherpesviruses 1 and 5

  • Juan Sebastian Quintero Barbosa,
  • Carlos Javier Alméciga-Díaz,
  • Sandra E. Pérez and
  • María Fernanda Gutierrez

29 June 2023

Infectious bovine rhinotracheitis (IBR) and bovine meningoencephalitis are caused by Bovine alphaherpesvirus (BoHV) types 1 and 5, which seriously threaten the global cattle industry. Vaccination to improve immunity is the most direct and effective m...

  • Feature Paper
  • Review
  • Open Access
12 Citations
7,931 Views
24 Pages

Viral Diseases in Water Buffalo (Bubalus bubalis): New Insights and Perspectives

  • Julio Martínez-Burnes,
  • Hugo Barrios-García,
  • Verónica Carvajal-de la Fuente,
  • Belkis Corona-González,
  • Dasiel Obregón Alvarez and
  • Dora Romero-Salas

9 March 2024

The water buffalo (Bubalus bubalis) has great adaptability to rustic environments and more variable conditions than cattle, who generally share the habitat. Diseases carried by buffaloes are relatively unknown and ignored and could be transmissible;...

  • Article
  • Open Access
17 Citations
6,526 Views
16 Pages

Characterization of BoHV-1 gG-/tk-/gE- Mutant in Differential Protein Expression, Virulence, and Immunity

  • Marawan A. Marawan,
  • Mingliang Deng,
  • Chen Wang,
  • Yingyu Chen,
  • Changmin Hu,
  • Jianguo Chen,
  • Xi Chen,
  • Huanchun Chen and
  • Aizhen Guo

27 October 2021

Infectious bovine rhinotracheitis (IBR), caused by bovine alphaherpesvirus 1 (BoHV-1), is an important disease affecting cattle worldwide resulting in great economic losses. Marker vaccines are effective in controlling infectious diseases including I...

  • Article
  • Open Access
17 Citations
3,104 Views
17 Pages

Validation of a Commercial Indirect ELISA Kit for the Detection of Bovine alphaherpesvirus1 (BoHV-1)-Specific Glycoprotein E Antibodies in Bulk Milk Samples of Dairy Cows

  • Cecilia Righi,
  • Carmen Iscaro,
  • Laura Ferroni,
  • Sergio Rosati,
  • Claudia Pellegrini,
  • Chiara Nogarol,
  • Elisabetta Rossi,
  • Annalisa Dettori,
  • Francesco Feliziani and
  • Stefano Petrini

22 June 2022

In this study, we validated a commercial indirect enzyme-linked immunosorbent assay (ELISA) to detect antibodies to glycoprotein E (gE) of Bovine alphaherpesvirus 1 (BoHV-1) in bulk milk (BM) samples using the OIE Manual of Diagnostic Tests and Vacci...

  • Article
  • Open Access
567 Views
21 Pages

A Multi-Epitope Recombinant Vaccine Candidate Against Bovine Alphaherpesvirus 1 and 5 Elicits Robust Immune Responses in Mice and Rabbits

  • Aline Aparecida Silva Barbosa,
  • Samille Henriques Pereira,
  • Mateus Laguardia-Nascimento,
  • Amanda Borges Ferrari,
  • Laura Jorge Cox,
  • Raissa Prado Rocha,
  • Victor Augusto Teixeira Leocádio,
  • Ágata Lopes Ribeiro,
  • Karine Lima Lourenço and
  • Flávio Guimarães Da Fonseca
  • + 1 author

30 October 2025

Background/Objectives: Varicellovirus bovinealpha1 and Varicellovirus bovinealpha5 (BoAHV-1 and BoAHV-5), respectively, are widely distributed pathogens that cause distinct clinical conditions in cattle including infectious bovine rhinotracheitis, in...

  • Article
  • Open Access
17 Citations
2,689 Views
14 Pages

Antiviral Property of the Fungal Metabolite 3-O-Methylfunicone in Bovine Herpesvirus 1 Infection

  • Filomena Fiorito,
  • Claudia Cerracchio,
  • Maria Michela Salvatore,
  • Francesco Serra,
  • Alessia Pucciarelli,
  • Maria Grazia Amoroso,
  • Rosario Nicoletti and
  • Anna Andolfi

Bovine herpesvirus type-1 (BoHV-1) is a widespread pathogen that provokes infectious rhinotracheitis and polymicrobial infections in cattle, resulting in serious economic losses to the farm animal industry and trade restrictions. To date, non-toxic a...

  • Article
  • Open Access
1 Citations
2,286 Views
17 Pages

Effects of Vitamin and Mineral Supplementation During Gestation in Beef Heifers on Immunoglobulin Concentrations in Colostrum and Immune Responses in Naturally and Artificially Reared Calves

  • Jennifer L. Hurlbert,
  • Friederike Baumgaertner,
  • Kerri A. Bochantin-Winders,
  • Isabella M. Jurgens,
  • Kevin K. Sedivec and
  • Carl R. Dahlen

7 December 2024

Two experiments assessed the effects of providing a vitamin and mineral supplement to gestating beef heifers on concentrations of immunoglobulins (Ig) in colostrum and calf serum 24 h after feeding maternal colostrum (Exp. 1) or a colostrum-replaceme...

  • Brief Report
  • Open Access
5 Citations
2,692 Views
8 Pages

A Real-Time Recombinase Polymerase Amplification Assay for Specific Detection of Lumpy Skin Disease Virus

  • Qi Zhai,
  • Xia Zhou,
  • Liyin Du,
  • Nan Yang,
  • Yakun Lou,
  • Jianying Liu and
  • Shaolun Zhai

19 October 2023

Lumpy skin disease virus (LSDV) infection, accompanied by loss of hide quality, poor reproductive efficiency, consistent degenerative emaciation, and milk yield reduction of animals, causes severe economic implications in endemic zones. The heterolog...

  • Article
  • Open Access
10 Citations
4,226 Views
9 Pages

Management Factors Influence Animal Welfare and the Correlation to Infectious Diseases in Dairy Cows

  • Francesca Licitra,
  • Laura Perillo,
  • Francesco Antoci,
  • Giuseppe Piccione,
  • Claudia Giannetto,
  • Rosario Salonia,
  • Elisabetta Giudice,
  • Vincenzo Monteverde and
  • Giuseppe Cascone

20 November 2021

The present study assessed dairy cow welfare through the application of the Italian National Animal Welfare Reference Center (CReNBA) checklist in 36 dairy farms located in Ragusa (Italy) subjected to two different management conditions, housing with...

  • Review
  • Open Access
42 Citations
8,047 Views
15 Pages

2 January 2019

To date, in countries where infectious bovine rhinotracheitis (IBR) is widespread, its control is associated with deleted marker vaccines. These products lack one or more genes responsible for the synthesis of glycoproteins or enzymes. In Europe, the...

  • Article
  • Open Access
1 Citations
1,281 Views
19 Pages

Bovine respiratory disease complex (BRDC) is one of the primary causes of morbidity, mortality, and economic loss in cattle worldwide. Accurate and rapid identification of causative pathogenic agents is essential for effective disease management and...

  • Article
  • Open Access
4 Citations
2,121 Views
14 Pages

Evaluation of Hematological Profiles and Monocyte Subpopulations in Water Buffalo Calves after Immunization with Two Different IBR Marker Vaccines and Subsequent Infection with Bubaline alphaherpesvirus-1

  • Francesco Grandoni,
  • Jamal Hussen,
  • Federica Signorelli,
  • Francesco Napolitano,
  • Maria Carmela Scatà,
  • Immacolata De Donato,
  • Giovanna Cappelli,
  • Giorgio Galiero,
  • Carlo Grassi and
  • Esterina De Carlo
  • + 3 authors

23 August 2023

Bubaline alphaherpesvirus-1 (BuAHV-1) and Bovine alphaherpesvirus-1 (BoAHV-1) are respiratory viruses that can cause an infection known as “Infectious Bovine Rhinotracheitis” (IBR) in both water buffalo and bovine species. As the main dis...

  • Article
  • Open Access
9 Citations
3,307 Views
14 Pages

Effects of an Appeasing Substance Application at Weaning on Growth, Stress, Behavior, and Response to Vaccination of Bos indicus Calves

  • Douglas Gomes Vieira,
  • Marcelo Vedovatto,
  • Henrique Jorge Fernandes,
  • Eduardo de Assis Lima,
  • Marcella Candia D’Oliveira,
  • Uriel de Almeida Curcio,
  • Juliana Ranches,
  • Matheus Fellipe Ferreira,
  • Osvaldo Alex de Sousa and
  • Bruno Ieda Cappellozza
  • + 1 author

27 September 2023

An analog of a bovine-appeasing substance (BAS) was previously demonstrated to have calming effects, and it could be an alternative to alleviate the stress caused by weaning. Thus, the objective of this study was to evaluate the effects of BAS admini...