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16 pages, 3259 KB  
Article
An Experimental and Theoretical Study of the Effective Length of Embedded Scintillator Materials in End-Constructed Optical Fiber Radiation Sensing Probes
by Yichen Li, Yong Feng, Jingjing Wang, Bo He, Ziyin Chen, Haojie Yang, Qieming Shi, Wenjing Hao, Jinqian Qian, Jiashun Luo, Jinhui Cui, Yongjun Liu, Tao Geng, Elfed Lewis and Weimin Sun
Sensors 2025, 25(21), 6704; https://doi.org/10.3390/s25216704 (registering DOI) - 2 Nov 2025
Abstract
Optical fiber radiation sensing probes made using inorganic scintillator materials have notable advantages in achieving high spatial resolution and building sensing arrays due to their small size and excellent linearity, serving as a key tool for dose measurement in precision radiotherapy. This study [...] Read more.
Optical fiber radiation sensing probes made using inorganic scintillator materials have notable advantages in achieving high spatial resolution and building sensing arrays due to their small size and excellent linearity, serving as a key tool for dose measurement in precision radiotherapy. This study establishes a theoretical model for scintillator luminescence coupling into optical fibers, and derives a fluorescence intensity calculation formula based on the fiber’s numerical aperture and fluorescence self-absorption. The light intensity response to scintillator length for different absorption coefficients is established based on numerical simulation, providing a nonlinear fitting equation, resulting in a novel “effective length of scintillator” concept. Five probes with scintillator lengths of 0.2 mm, 0.5 mm, 1.0 mm, 1.5 mm, and 2.0 mm were prepared in the laboratory using a 3:1 mass ratio mixture of UV-setting epoxy and Gd2O2S:Tb powder. Tests in a clinical radiation delivery setting showed good agreement between experimental data and theory, confirming optimum effective length of the scintillator as 0.62 mm. This study indicates that inorganic scintillators for end-constructed probes do need not need to be excessively long. Analyzing the effective length can reduce scintillator usage, simplify fabrication and processing, and enhance the probe’s spatial resolution without decreasing the signal-to-noise ratio, thus offering new insights for optimizing optical fiber radiation probes. Full article
16 pages, 1592 KB  
Article
Novel Model for Stomatal Conductance: Enhanced Accuracy Under Variable Irradiance and CO2 in C3 Plant Species
by Zipiao Ye, Ting An, Xiaolong Yang, Huajing Kang and Fubiao Wang
Biology 2025, 14(11), 1501; https://doi.org/10.3390/biology14111501 - 27 Oct 2025
Viewed by 230
Abstract
This study analyzes stomatal conductance (gsc) in Trifolium repens L., Lolium perenne L., and Triticum aestivum L. under varying environmental conditions. Light-response curves for photosynthesis (AnI) at 420 μmol mol−1 CO2 were used [...] Read more.
This study analyzes stomatal conductance (gsc) in Trifolium repens L., Lolium perenne L., and Triticum aestivum L. under varying environmental conditions. Light-response curves for photosynthesis (AnI) at 420 μmol mol−1 CO2 were used to determine saturating irradiance (Isat) using a light-response model for photosynthesis, and CO2-response curves for photosynthesis (AnCi) were measured at Isat and half Isat for these C3 plant species. The Ball–Woodrow–Berry (BWB) model, Medlyn model, and a new model were compared for their ability to describe the net photosynthetic rate (An) relative to gsc under changing irradiance or CO2. The BWB model overestimated gsc response, simplifying stomatal behavior, while the Medlyn model deviated at high An values, indicating limitations in dynamic responses. The new model showed a better empirical fit under the tested conditions, achieving high R2 values and low AIC values across all three species, and demonstrated a strong alignment with empirical data. Our findings highlight the complexity of gsc regulation and the need for improved models to better represent stomatal dynamics under different environmental conditions. This research is vital for optimizing water use efficiency, enhancing crop productivity, and understanding plant resilience to climate change. Full article
(This article belongs to the Section Plant Science)
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24 pages, 4973 KB  
Article
An Enhanced Method for Optical Imaging Computation of Space Objects Integrating an Improved Phong Model and Higher-Order Spherical Harmonics
by Qinyu Zhu, Can Xu, Yasheng Zhang, Yao Lu, Xia Wang and Peng Li
Remote Sens. 2025, 17(21), 3543; https://doi.org/10.3390/rs17213543 - 26 Oct 2025
Viewed by 210
Abstract
Space-based optical imaging detection serves as a crucial means for acquiring characteristic information of space objects, with the quality and resolution of images directly influencing the accuracy of subsequent missions. Addressing the scarcity of datasets in space-based optical imaging, this study introduces a [...] Read more.
Space-based optical imaging detection serves as a crucial means for acquiring characteristic information of space objects, with the quality and resolution of images directly influencing the accuracy of subsequent missions. Addressing the scarcity of datasets in space-based optical imaging, this study introduces a method that combines an improved Phong model and higher-order spherical harmonics (HOSH) for the optical imaging computation of space objects. Utilizing HOSH to fit the light field distribution, this approach comprehensively considers direct sunlight, earthshine, reflected light from other extremely distant celestial bodies, and multiple scattering from object surfaces. Through spectral reflectance experiments, an improved Phong model is developed to calculate the optical scattering characteristics of space objects and to retrieve common material properties such as metallicity, roughness, index of refraction (IOR), and Alpha for four types of satellite surfaces. Additionally, this study designs two sampling methods: a random sampling based on the spherical Fibonacci function (RSSF) and a sequential frame sampling based on predefined trajectories (SSPT). Through numerical analysis of the geometric and radiative rendering pipeline, this method simulates multiple scenarios under both high-resolution and wide-field-of-view operational modes across a range of relative distances. Simulation results validate the effectiveness of the proposed approach, with average rendering speeds of 2.86 s per frame and 1.67 s per frame for the two methods, respectively, demonstrating the capability for real-time rapid imaging while maintaining low computational resource consumption. The data simulation process spans six distinct relative distance intervals, ensuring that multi-scale images retain substantial textural features and are accompanied by attitude labels, thereby providing robust support for algorithms aimed at space object attitude estimation, and 3D reconstruction. Full article
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18 pages, 291 KB  
Article
Comparative Analysis of Psychological Profiles and Physical Functioning in Addicted and Non-Addicted Male Prisoners: A Pilot Study
by Michalina Błażkiewicz, Jacek Wąsik, Justyna Kędziorek, Wiktoria Bandura, Jakub Kacprzak, Kamil Radecki, Karolina Radecka and Dariusz Mosler
J. Clin. Med. 2025, 14(21), 7579; https://doi.org/10.3390/jcm14217579 - 25 Oct 2025
Viewed by 254
Abstract
Background/Objectives: The prison environment presents a unique context for examining the impact of addiction on physical and psychological functioning. Individuals with substance use disorders (SUDs) are overrepresented in correctional facilities and often experience greater emotional difficulties and impaired physical capacity. This study [...] Read more.
Background/Objectives: The prison environment presents a unique context for examining the impact of addiction on physical and psychological functioning. Individuals with substance use disorders (SUDs) are overrepresented in correctional facilities and often experience greater emotional difficulties and impaired physical capacity. This study aimed to conduct a comparative analysis of psychological and functional profiles between addicted and non-addicted male inmates in a semi-open correctional facility. Methods: The study included 47 male prisoners (19 addicted, 28 non-addicted). Physical performance was assessed using the Countermovement Jump (CMJ), handgrip strength, the Functional Movement Screen (FMS), and the FitLight reaction time test. Psychological functioning was evaluated using six standardized questionnaires: problem-focused, emotion-focused, and avoidant coping strategies, depression (PHQ-9), perceived stress (PSS-10), and self-compassion (SCS). Results: No statistically significant differences (p > 0.05) were found between addicted and non-addicted inmates in physical performance parameters. Addicted individuals demonstrated slightly higher handgrip strength with lower variability, while non-addicted inmates showed slightly better lower-body power in the CMJ test. Functional movement quality and reaction speed were similar between groups. Psychological assessments also revealed no significant differences between the groups. Coping styles, depressive symptoms, perceived stress levels, and self-criticism scores were comparable in both populations. In the addicted group, deeper squats correlated with lower stress (rho = −0.46, p = 0.047), and better hurdle step performance correlated with emotion-focused coping (rho = 0.46, p = 0.048). Conclusions: Although no statistically significant differences were found between addicted and non-addicted male inmates in the assessed physical and psychological outcomes, the limited sample size and context-specific nature of this pilot study suggest that these findings should be viewed as preliminary and interpreted with caution. Nonetheless, the observed associations between physical performance and psychological variables indicate subtle interconnections between motor capacity, stress perception, and coping mechanisms that merit further investigation in larger, longitudinal studies. Full article
(This article belongs to the Special Issue Substance and Behavioral Addictions: Prevention and Diagnosis)
17 pages, 6416 KB  
Article
Novel High-Contrast Photoacoustic Imaging Method for Cancer Cell Monitoring Based on Dual-Wavelength Confocal Metalenses
by Zixue Chen, Ruihao Zhang, Hongbin Zhang, Bingqiang Zhang, Lei Qin, Jiansen Du, Tao Zhao and Bin Wang
Photonics 2025, 12(11), 1053; https://doi.org/10.3390/photonics12111053 - 24 Oct 2025
Viewed by 317
Abstract
This study proposes a high-contrast photoacoustic (PA) imaging methodology based on a dual-wavelength confocal metalens, designed to monitor the dissemination of cancer cells and to inform subsequent cancer treatment strategies. The metalens is composed of two metasurfaces that perform filtering and focusing functions, [...] Read more.
This study proposes a high-contrast photoacoustic (PA) imaging methodology based on a dual-wavelength confocal metalens, designed to monitor the dissemination of cancer cells and to inform subsequent cancer treatment strategies. The metalens is composed of two metasurfaces that perform filtering and focusing functions, effectively reducing the cross-talk between the two wavelengths of light in space and achieving a confocal effect. Furthermore, to minimize process complexity, a uniform material system of silicon dioxide (SiO2) and titanium dioxide (TiO2) is employed across the different metasurfaces of the metalens. The designed metalens has a radius of 25 µm and an operational focal length of 98.5 µm. The results confirm that this dual-metasurface design achieves high focusing efficiency alongside precise focusing capability, with the deviations of the actual focal lengths for both beams from the design values being within 1.5 µm. Additionally, this study developed a skin tissue model and simulated multi-wavelength photoacoustic imaging of cancer cells within the human body by integrating theories of radiative transfer, photothermal conversion, and the wave equation. The results demonstrate that the enhancement trend of the reconstructed signal closely matches the original signal, confirming the model’s excellent fitting performance. The sound pressure values generated by cancer cells are significantly higher than those of normal cells, proving that this method can effectively distinguish cancerous tissue from healthy tissue. This research provides new theoretical support and methodological foundations for the clinical application of multi-wavelength photoacoustic imaging technology. Full article
(This article belongs to the Special Issue The Principle and Application of Photonic Metasurfaces)
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29 pages, 7029 KB  
Article
A Census of Chemically Peculiar Stars in Stellar Associations
by Lukas Kueß and Ernst Paunzen
Astronomy 2025, 4(4), 20; https://doi.org/10.3390/astronomy4040020 - 22 Oct 2025
Viewed by 193
Abstract
The pre-main-sequence evolution of the chemically peculiar (CP) stars on the upper main sequence is still a vast mystery and not well understood. Our analysis of young associations and open clusters aims to find (very) young CP stars to try to put a [...] Read more.
The pre-main-sequence evolution of the chemically peculiar (CP) stars on the upper main sequence is still a vast mystery and not well understood. Our analysis of young associations and open clusters aims to find (very) young CP stars to try to put a lower boundary on the age of such objects. Using three catalogues of open clusters and associations, we determined membership probabilities using HDBSCAN. The hot stars from this selection were submitted to synthetic Δa photometry, spectral, and light curve classification to determine which ones are CP stars and candidates. Subsequently, we used spectral energy distribution fitting and emission line analysis to check for possible PMS CP stars. The results were compared to the literature. We detected 971 CP stars and candidates in 217 clusters and associations. A relatively large fraction, ∼10% of those, show characteristics of PMS CP stars. This significantly expands the known list of candidate PMS CP stars, bringing us closer to solving the mystery of their origin. Full article
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19 pages, 509 KB  
Article
Symmetric Equilibrium Bagging–Cascading Boosting Ensemble for Financial Risk Early Warning
by Yao Zou, Yuan Yuan, Chen Zhu and Chenhui Yu
Symmetry 2025, 17(10), 1779; https://doi.org/10.3390/sym17101779 - 21 Oct 2025
Viewed by 303
Abstract
Financial risk early warning systems provide critical corporate financial status information to stakeholders, including corporate managers, investors, regulatory agencies, and other interested parties, enabling informed decision-making. This study proposes a corporate financial risk early warning model based on a bagging–cascading–boosting architecture, which can [...] Read more.
Financial risk early warning systems provide critical corporate financial status information to stakeholders, including corporate managers, investors, regulatory agencies, and other interested parties, enabling informed decision-making. This study proposes a corporate financial risk early warning model based on a bagging–cascading–boosting architecture, which can be used to predict the financial risk of a firm. The model performance is improved by integrating the residual fitting characteristics of LightGBM, the variance suppression mechanism of bagging, and the adaptive expansion ability of the cascade framework. Evaluated on 46 financial indicators from 2826 A-share-listed companies, the model demonstrates superior performance in AUC and F1-score metrics, outperforming traditional statistical methods and standalone machine-learning models. The methodological innovation lies in its tripartite mechanism: LightGBM ensures low-bias prediction, bagging controls variance, and the cascading structure dynamically adapts to data complexity, maintaining 94.09% AUC robustness, even when training data is reduced to 50%. Empirical results confirm this “ensemble-of-ensembles” framework effectively identifies Special Treatment (ST) firms, delivering early risk alerts for management while supporting investment decisions and regulatory risk mitigation. Full article
(This article belongs to the Section Computer)
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29 pages, 13306 KB  
Article
Building Outline Extraction via Topology-Aware Loop Parsing and Parallel Constraint from Airborne LiDAR
by Ke Liu, Hongchao Ma, Li Li, Shixin Huang, Liang Zhang, Xiaoli Liang and Zhan Cai
Remote Sens. 2025, 17(20), 3498; https://doi.org/10.3390/rs17203498 - 21 Oct 2025
Viewed by 317
Abstract
Building outlines are important vector data for various applications, but due to the uneven point density and complex building structures, extracting satisfactory building outlines from airborne light detection and ranging point cloud data poses significant challenges. Thus, a building outline extraction method based [...] Read more.
Building outlines are important vector data for various applications, but due to the uneven point density and complex building structures, extracting satisfactory building outlines from airborne light detection and ranging point cloud data poses significant challenges. Thus, a building outline extraction method based on topology-aware loop parsing and parallel constraint is proposed. First, constrained Delaunay triangulation (DT) is used to organize scattered projected building points, and initial boundary points and edges are extracted based on the constrained DT. Subsequently, accurate semantic boundary points are obtained by parsing the topology-aware loops searched from an undirected graph. Building dominant directions are estimated through angle normalization, merging, and perpendicular pairing. Finally, outlines are regularized using the parallel constraint-based method, which simultaneously considers the fitness between the dominant direction and boundary points, and the length of line segments. Experiments on five datasets, including three datasets provided by ISPRS and two datasets with high-density point clouds and complex building structures, verify that the proposed method can extract sequential and semantic boundary points, with over 97.88% correctness. Additionally, the regularized outlines are attractive, and most line segments are parallel or perpendicular. The RMSE, PoLiS, and RCC metrics are better than 0.94 m, 0.84 m, and 0.69 m, respectively. The extracted building outlines can be used for building three-dimensional (3D) reconstruction. Full article
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13 pages, 2505 KB  
Article
Influence of Foot and Legwear Color on Lower-Limb Temperature in Baseball Players Under Heat Stress
by Manato Seguchi, Yoko Iio, Saimi Yamamoto, Tsukasa Yamamoto, Harumi Ejiri, Yuka Aoyama and Morihiro Ito
Sports 2025, 13(10), 369; https://doi.org/10.3390/sports13100369 - 21 Oct 2025
Viewed by 401
Abstract
Background: Elevated global temperatures increase the risk of heat-stroke among athletes exercising in hot conditions. Japanese high school baseball tournaments occur during peak summer, raising concerns regarding heat-related health issues. We examined whether the color of footwear and legwear affects lower-limb temperature, exploring [...] Read more.
Background: Elevated global temperatures increase the risk of heat-stroke among athletes exercising in hot conditions. Japanese high school baseball tournaments occur during peak summer, raising concerns regarding heat-related health issues. We examined whether the color of footwear and legwear affects lower-limb temperature, exploring approaches to prevent heat-related health problems. Methods: Eight mannequin legs were fitted with shoes, socks, and baseball stirrup socks in white or black combinations. Plantar and shin surface temperatures were recorded for 120 min on both dirt and artificial turf at wet-bulb globe temperatures above 30 °C and compared across color combinations. Reflectance spectra of shin legwear were also measured. Results: Plantar and shin surface temperatures increased under all conditions. On the dirt field, mannequins wearing all-black gear (shoe, sock, and baseball stirrup sock) exhibited plantar temperatures exceeding 45 °C and shin temperatures over 50 °C. The highest shin temperature occurred with the white shoe/black baseball stirrup sock combination. Temperature increases were smaller for all-white items compared with all-black items. Reflectance spectra showed that white baseball stirrup socks strongly reflected both visible and infrared light. Conclusions: Footwear and legwear color significantly influence lower-limb temperature increases during baseball games in summer heat, especially when wearing all-black items. White gear may help prevent heat-related health problems and improve performance in baseball and other outdoor sports. Full article
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22 pages, 6783 KB  
Article
Parsing Glomerular and Tubular Structure Variability in High-Throughput Kidney Organoid Culture
by Kristiina Uusi-Rauva, Anniina Pirttiniemi, Antti Hassinen, Ras Trokovic, Sanna Lehtonen, Jukka Kallijärvi, Markku Lehto, Vineta Fellman and Per-Henrik Groop
Methods Protoc. 2025, 8(5), 125; https://doi.org/10.3390/mps8050125 - 19 Oct 2025
Viewed by 493
Abstract
High variability in stem cell research is a well-known limiting phenomenon, with technical variation across experiments and laboratories often surpassing variation caused by genotypic effects of induced pluripotent stem cell (iPSC) lines. Evaluation of kidney organoid protocols and culture conditions across laboratories remains [...] Read more.
High variability in stem cell research is a well-known limiting phenomenon, with technical variation across experiments and laboratories often surpassing variation caused by genotypic effects of induced pluripotent stem cell (iPSC) lines. Evaluation of kidney organoid protocols and culture conditions across laboratories remains scarce in the literature. We used the original air-medium interface protocol to evaluate kidney organoid success rate and reproducibility with several human iPSC lines, including a novel patient-derived GRACILE syndrome iPSC line. Organoid morphology was assessed with light microscopy and immunofluorescence-stained maturing glomerular and tubular structures. The protocol was further adapted to four microplate-based high-throughput approaches utilizing spheroid culture steps. Quantitative high-content screening analysis of the nephrin-positive podocytes and ECAD-positive tubular cells revealed that the choice of approach and culture conditions were significantly associated with structure development. The culture approach, iPSC line, experimental replication, and initial cell number explained 35–77% of the variability in the logit-transformed proportion of nephrin and ECAD-positive area, when fitted into multiple linear models. Our study highlights the benefits of high-throughput culture and multivariate techniques to better distinguish sources of technical and biological variation in morphological analysis of organoids. Our microplate-based high-throughput approach is easily adaptable for other laboratories to combat organoid size variability. Full article
(This article belongs to the Section Omics and High Throughput)
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19 pages, 6255 KB  
Article
Data–Physics-Driven Multi-Point Hybrid Deformation Monitoring Model Based on Bayesian Optimization Algorithm–Light Gradient-Boosting Machine
by Lei Song and Yating Hu
Water 2025, 17(20), 2926; https://doi.org/10.3390/w17202926 - 10 Oct 2025
Viewed by 487
Abstract
Single-point deformation monitoring models fail to reflect the structural integrity of the concrete gravity dams, and traditional regression methods also have shortcomings in capturing complex nonlinear relationships among variables. To solve these problems, this paper develops a data–physics-driven multi-point hybrid deformation monitoring model [...] Read more.
Single-point deformation monitoring models fail to reflect the structural integrity of the concrete gravity dams, and traditional regression methods also have shortcomings in capturing complex nonlinear relationships among variables. To solve these problems, this paper develops a data–physics-driven multi-point hybrid deformation monitoring model based on Bayesian Optimization Algorithm–Light Gradient-Boosting Machine (BOA-LightGBM). Building upon conventional single-point models, spatial coordinates are incorporated as explanatory variables to derive a multi-point deformation monitoring model that accounts for spatial correlations. Subsequently, the finite element method (FEM) is employed to simulate the hydrostatic component at each monitoring point under actual reservoir water levels. Finally, a hybrid model is constructed by integrating the derived mathematical expression, simulated hydrostatic components, and the BOA-LightGBM algorithm. A case study demonstrates that the proposed model effectively incorporates spatial deformation characteristics within dam sections and achieves satisfactory fitting and prediction accuracy compared to traditional single-point monitoring models. With further refinement and extension, the proposed modeling theory and methodology presented in this study can also provide valuable references for safety monitoring of other hydrostatic structures. Full article
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14 pages, 2096 KB  
Article
Attention-Enhanced Semantic Segmentation for Substation Inspection Robot Navigation
by Changqing Cai, Yongkang Yang, Kaiqiao Tian, Yuxin Yan, Kazuyuki Kobayashi and Ka C. Cheok
Sensors 2025, 25(19), 6252; https://doi.org/10.3390/s25196252 - 9 Oct 2025
Viewed by 445
Abstract
Outdoor substations present complex conditions such as uneven terrain, strong illumination variations, and frequent occlusions, which pose significant challenges for autonomous robotic inspection. To address these issues, we develop an embedded inspection robot that integrates attention-enhanced semantic segmentation with GPS-assisted navigation for reliable [...] Read more.
Outdoor substations present complex conditions such as uneven terrain, strong illumination variations, and frequent occlusions, which pose significant challenges for autonomous robotic inspection. To address these issues, we develop an embedded inspection robot that integrates attention-enhanced semantic segmentation with GPS-assisted navigation for reliable operation. A lightweight DeepLabV3+ model is improved with ECA-SimAM and CBAM attention modules and further extended with a GPS-guided attention component that incorporates coarse location priors to refine feature focus and improve boundary recognition under challenging lighting and occlusion. The segmentation outputs are used to generate real-time road masks and navigation lines via center-of-mass and least-squares fitting, while RTK-GPS provides global positioning and triggers waypoint-based behaviors such as turning and stopping. Experimental results show that the proposed method achieves 85.26% mean IoU and 89.45% mean pixel accuracy, outperforming U-Net, PSPNet, HRNet, and standard DeepLabV3+. Deployed on an embedded platform and validated in real substations, the system demonstrates both robustness and scalability for practical infrastructure inspection tasks. Full article
(This article belongs to the Section Sensors and Robotics)
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19 pages, 2825 KB  
Article
The Impact of Information Layout and Auxiliary Instruction Display Mode on the Usability of Virtual Fitting Interaction Interfaces
by Xingmin Lin and Peiling Pan
Information 2025, 16(10), 862; https://doi.org/10.3390/info16100862 - 4 Oct 2025
Viewed by 440
Abstract
With the widespread adoption of virtual fitting technology in e-commerce and fashion, optimizing user experience through interface design has become increasingly critical. However, research on the usability of virtual fitting interaction interfaces remains limited. Current interfaces frequently suffer from disorganized information layouts and [...] Read more.
With the widespread adoption of virtual fitting technology in e-commerce and fashion, optimizing user experience through interface design has become increasingly critical. However, research on the usability of virtual fitting interaction interfaces remains limited. Current interfaces frequently suffer from disorganized information layouts and ambiguous auxiliary instructions, reducing efficiency and immersion. This study systematically investigates the effects of information layout (matrix layout, list layout, horizontal layout) and auxiliary instruction display mode (positive polarity: dark content on light background; negative polarity: light content on dark background) on user task performance and subjective experience. A between-subjects experiment was conducted with 60 participants across six conditions. Participants performed a series of tasks, and data were collected on task completion time, subjective ratings, and Technology Acceptance Model responses. Analyses were conducted using two-way ANOVA. The main findings were as follows: (1) The matrix layout demonstrated higher efficiency in multi-target search and complex decision-making tasks, and also received higher subjective ratings for perceived ease of use. (2) The positive polarity display mode demonstrated better performance in single-information search and cognitively intensive tasks, coupled with higher subjective ratings for interface rationality and information clarity. (3) A significant interaction effect was identified between information layout and display mode. The matrix layout combined with positive polarity improved efficiency, whereas the list layout with negative polarity impaired task performance. The horizontal layout was also rated lower for operational fluency. These findings provide practical guidance for designing virtual fitting interfaces that enhance both performance and subjective user experience. Full article
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11 pages, 1279 KB  
Article
Horizontally Transferred Carotenoid Genes Associated with Light-Driven ATP Synthesis to Promote Cold Adaptation in Pea Aphid, Acyrthosiphon pisum
by Jin Miao, Huiling Li, Yun Duan, Zhongjun Gong, Xiaoling Tan, Ruijie Lu, Muhammad Bilal and Yuqing Wu
Insects 2025, 16(10), 1013; https://doi.org/10.3390/insects16101013 - 30 Sep 2025
Viewed by 669
Abstract
The pea aphid, Acyrthosiphon pisum, possesses horizontally acquired fungal carotenoid biosynthesis genes, enabling de novo production of carotenoids. Although carotenoids are known to contribute to photo-protection and coloration, their potential role in energy metabolism and population fitness under thermal stress is still [...] Read more.
The pea aphid, Acyrthosiphon pisum, possesses horizontally acquired fungal carotenoid biosynthesis genes, enabling de novo production of carotenoids. Although carotenoids are known to contribute to photo-protection and coloration, their potential role in energy metabolism and population fitness under thermal stress is still unclear. This study investigated the interactive effects of temperature and light intensity on energy homeostasis and life-history traits in A. pisum. Using controlled environmental regimes, we demonstrate that light intensity significantly influenced the ATP content, development, and reproductive output of A. pisum at 12 °C, but not at 22 °C. Under cold stress (12 °C), high light intensity (5000 lux) increased ATP content by 240%, shortened the pre-reproductive period by 46%, extended reproductive duration by 62%, and enhanced the net reproductive rate (R0) and intrinsic rate of increase (rₘ) compared to low light intensity (200 lux). These effects were abolished at the optimal temperature (22 °C), indicating a temperature-gated, light-dependent mechanism. Demographic analyses revealed that carotenoid-associated solar energy harvesting significantly improves fitness under cold conditions, likely compensating for metabolic depression. Our findings reveal a novel ecological adaptation in aphids, where horizontally transferred genes may enable light-driven energy supplementation during thermal stress. This study provides new insights into the physiological mechanisms underlying insect resilience to climate variability and highlights the importance of light as a key environmental factor in shaping life-history strategies in temperate agroecosystems. Full article
(This article belongs to the Section Insect Physiology, Reproduction and Development)
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15 pages, 856 KB  
Article
Integrating Fitbit Wearables and Self-Reported Surveys for Machine Learning-Based State–Trait Anxiety Prediction
by Archana Velu, Jayroop Ramesh, Abdullah Ahmed, Sandipan Ganguly, Raafat Aburukba, Assim Sagahyroon and Fadi Aloul
Appl. Sci. 2025, 15(19), 10519; https://doi.org/10.3390/app151910519 - 28 Sep 2025
Viewed by 775
Abstract
Anxiety disorders represent a significant global health challenge, yet a substantial treatment gap persists, motivating the development of scalable digital health solutions. This study investigates the potential of integrating passive physiological data from consumer wearable devices with subjective self-reported surveys to predict state–trait [...] Read more.
Anxiety disorders represent a significant global health challenge, yet a substantial treatment gap persists, motivating the development of scalable digital health solutions. This study investigates the potential of integrating passive physiological data from consumer wearable devices with subjective self-reported surveys to predict state–trait anxiety. Leveraging the multi-modal, longitudinal LifeSnaps dataset, which captured “in the wild” data from 71 participants over four months, this research develops and evaluates a machine learning framework for this purpose. The methodology meticulously details a reproducible data curation pipeline, including participant-specific time zone harmonization, validated survey scoring, and comprehensive feature engineering from Fitbit Sense physiological data. A suite of machine learning models was trained to classify the presence of anxiety, defined by the State–Trait Anxiety Inventory (S-STAI). The CatBoost ensemble model achieved an accuracy of 77.6%, with high sensitivity (92.9%) but more modest specificity (48.9%). The positive predictive value (77.3%) and negative predictive value (78.6%) indicate balanced predictive utility across classes. The model obtained an F1-score of 84.3%, a Matthews correlation coefficient of 0.483, and an AUC of 0.709, suggesting good detection of anxious cases but more limited ability to correctly identify non-anxious cases. Post hoc explainability approaches (local and global) reveal that key predictors of state anxiety include measures of cardio-respiratory fitness (VO2Max), calorie expenditure, duration of light activity, resting heart rate, thermal regulation and age. While additional sensitivity analysis and conformal prediction methods reveal that the size of the datasets contributes to overfitting, the features and the proposed approach is generally conducive for reasonable anxiety prediction. These findings underscore the use of machine learning and ubiquitous sensing modalities for a more holistic and accurate digital phenotyping of state anxiety. Full article
(This article belongs to the Special Issue AI Technologies for eHealth and mHealth, 2nd Edition)
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