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Keywords = Echinops latifolius Tausch

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13 pages, 1553 KiB  
Review
A Review of the Phytochemistry and Biological Activities of Echinopsis Radix
by Na Sun, Yujing Wang, Shuo Ma, Huanhuan Kang, Caihong Zhou, Linxuan Jin, Xin Zhang, Yu Zhang, Yuhan Yuan and Penghua Shu
Molecules 2024, 29(10), 2267; https://doi.org/10.3390/molecules29102267 - 11 May 2024
Cited by 2 | Viewed by 1587
Abstract
The main varieties of Echinopsis Radix recorded in the Chinese Pharmacopoeia are the roots of Echinops latifolius Tausch or Echinops grijsii Hance. However, the chemical constituents and biological activities of this herb have not been reviewed. In order to clarify the chemical constituents [...] Read more.
The main varieties of Echinopsis Radix recorded in the Chinese Pharmacopoeia are the roots of Echinops latifolius Tausch or Echinops grijsii Hance. However, the chemical constituents and biological activities of this herb have not been reviewed. In order to clarify the chemical constituents of the main varieties of this herb and improve the quality of Chinese medicinal material resources, this paper systematically reviewed their chemical constituents and related biological activities. Phytochemical investigations reveal eighty-five compounds including fort y-nine thiophenes (149), eight flavonoids (5057), seven caffeic acids and its derivatives (5864), eight sesquiterpenoids (6572), and thirteen triterpenoids and other compounds (7385) were reported from Echinopsis Radix. The review of biological activities suggests that thiophenes are the main secondary metabolites of the medicinal material which exert antitumor, insecticidal and antifungal activities. In addition, caffeic acid and its derivatives and sesquiterpenes are potential active ingredients worthy of further study. This review provides an important scientific basis for the development of active ingredients and resource quality evaluation of Echinopsis Radix. Full article
(This article belongs to the Section Natural Products Chemistry)
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