Search Results (3)

Background/Objectives: Sternal pain after cardiac surgery results in considerable discomfort and may contribute to the development of chronic postoperative sternal pain syndrome. Parasternal intercostal plane blocks have been shown to improve postoperative sternal pain and can be an essential part of enhanced recovery after cardiac surgery (ERACS). This cohort study evaluated the postoperative impact of a single-shot deep parasternal intercostal plane block (PIPB) on the requirement of analgesic medication and pain sensation up to 48 h. Methods: This retrospective single-center analysis evaluates the postoperative acute pain in 157 patients undergoing off-pump coronary artery bypass (OPCAB) with median sternotomy. The additive analgesic effects of deep PIPB (38 patients) were compared to a group with standard therapy but without PIPB (119 patients). To strengthen the findings, a propensity score matching analysis was performed. Outcomes included the consumption of emergency pain agents (piritramide), the requirement of the total morphine equivalent (ME), time to extubation, and ICU length of stay. Furthermore, we examined pain sensation with evaluation by using the behavioral pain score (BPS) and numeric rating score (NRS) up to 48 h after extubation. Results: The deep PIPB reduced the piritramide administration 24 h and 48 h after OPCAB surgery. Moreover, the requirement of ME was 24 h and 48 h after bypass surgery also significantly decreased. The one-to-one propensity score matching confirmed our primary findings and showed a decreased requirement for intravenous agents. Additionally, we observed a reduced time for extubation and a decreased NRS rating. However, no significant changes were observed in ICU length of stay, incidence of nausea, and vomiting. Conclusions: Our data suggests that an ultrasound-guided single-shot deep PIPB can be a valuable tool for a multimodal analgesic protocol on patients undergoing OPCAB surgery. Full article

Background/Objectives: Regional anesthesia is an important part of Enhanced Recovery after Cardiac Surgery (ERACS) protocols designed to enhance analgesia, reduce opioid use, and improve postoperative outcomes. The deep parasternal intercostal plane (Deep-PIP) block is a fascial plane block in which local anesthetics are injected between the intercostal and transversus thoracis muscles to block neural transmission through the anterior cutaneous branches of the intercostal nerve. This study evaluates the impact of the Deep-PIP block in patients undergoing cardiac surgery via median sternotomy. Methods: In this retrospective cohort study, patients were divided into cohorts of 232 patients who had a block (BLOCK group) and 351 patients who did not receive a block (NOBlock group) using propensity score matching. Pain scores and opioid consumption over 24 h, extubation times, and ICU and hospital length of stay were compared for the two groups. Several subgroup analyses were also performed to evaluate the effects of block technique and block adjuvants. Results: While there was not a statistically significant difference in opioid consumption between the two groups, the BLOCK group had significantly lower pain scores, extubation times, and hospital length of stay. The subgroup analyses showed that modifications to block technique and use of block adjuvants were associated with reduced opioid consumption, but did not significantly affect pain scores, extubation time, or ICU or hospital length of stay. Conclusions: This study demonstrates the benefits of the deep parasternal intercostal plane block as part of an ERACS protocol. Routine implementation of the Deep-PIP block is reasonable given its potential benefits combined with its positive safety profile. Full article

Optimal fluid therapy during perioperative care as part of enhanced recovery after cardiac surgery (ERACS) should improve the outcome. Our objective was finding out the effects of fluid overload on outcome and mortality within a well-established ERACS program. All consecutive patients undergoing cardiac surgery between January 2020 and December 2021 were enrolled. According to ROC curve analysis, a cut-off of ≥7 kg (group M, n = 1198) and <7 kg (group L, n = 1015) was defined. A moderate correlation was shown between weight gain and fluid balance r = 0.4, and a simple linear regression was significant p < 0.0001, R² = 0.16. Propensity score matching showed that increased weight gain was associated with a longer hospital length of stay (LOS) (L 8 [3] d vs. M 9 [6] d, p < 0.0001), an increased number of patients who received pRBCs (L 311 (36%) vs. M 429 (50%), p < 0.0001), and a higher incidence of postoperative acute kidney injury (AKI) (L 84 (9.8%) vs. M 165 (19.2%), p < 0.0001). Weight gain can easily represent fluid overload. Fluid overload after cardiac surgery is common and is associated with prolonged hospital LOS and increases the incidence of AKI. Full article