Search Results (1,669)

African swine fever (ASF), a highly contagious and lethal viral disease caused by the African swine fever virus (ASFV), poses a severe threat to the global swine industry. Recent outbreaks across Asia, Europe, and the Caribbean are exacerbating the challenge. Current control measures rely mainly on early detection, culling and strict biosecurity practices, underscoring the urgent need for a safe and effective vaccine. Since the mid-1960s, diverse vaccine strategies, including inactivated, subunit, DNA/mRNA, vectored, and live attenuated virus (LAV) vaccines, have been explored. Inactivated vaccines have consistently failed to confer protection due to insufficient functional antigen presentation and weak cellular immune activation. Subunit vaccines targeting single or multiple ASFV antigens have also shown limited success, often failing to induce sterile or long-lasting immunity. Among these approaches, LAV vaccines have demonstrated the greatest promise in eliciting robust and durable immune responses. However, major knowledge gaps remain regarding ASFV biology, ASFV–host interactions, ASFV immune evasion mechanisms, protective and cross-protective immunity, stable cell lines for LAV production, virulence reversion of LAVs, and the lack of harmonized standards for evaluating vaccine safety and efficacy, all of which impede the development of safe and broadly effective ASF vaccines. This narrative review summarizes recent advances in ASF vaccine research and highlights the critical obstacles that must be overcome to achieve successful ASF vaccine development. Full article

Propagating easterly waves (EW) are analyzed here, within the dynamical environment of the Caribbean Low-Level Jet (CLLJ) using radiosondes from the Organization of Tropical East Pacific Convection (OTREC) field campaign, ERA5 reanalysis, and lightning from the World Wide Lightning Location Network (WWLLN) over $5^{\circ }$–${20}^{\circ }$ N, ${60}^{\circ }$–${100}^{\circ }$ W during 21 August–30 September 2019. Radiosondes resolve the vertical structure of the waves at San Andrés (Colombia), Limón and Santa Cruz–Guanacaste (Costa Rica), while ERA5 provides spatial–temporal continuity and vertically integrated diagnostics—namely, the vertically integrated moisture flux divergence (VIMFD) and the vertically integrated geopotential flux divergence (VIGFD). Lightning from WWLLN and precipitation from ERA5 and the Integrated Multi-satellite Retrievals for the Global Precipitation Measurement mission (GPM IMERG) offer independent convective proxies to track disturbances. Mean profiles from radiosondes and ERA5 show strong agreement at Limón and Guanacaste and some differences at San Andrés, yet all datasets capture coherent, phase-locked anomalies in zonal wind, meridional wind, temperature, humidity, vertical velocity and vorticity used to diagnose EW–CLLJ interactions. VIMFD, VIGFD, lightning and precipitation exhibit westward-propagating cores that align with the above anomalies, indicating that organized convection is coupled to the disturbances, whereas the mean state preconditions the environment to enable wave-induced upward motion. A robust vertical adjustment of the CLLJ is documented: the core shifts from near 925 hPa over the Caribbean Sea to about 700 hPa over the Eastern Tropical Pacific ($\Delta p\sim 150$ hPa). This feature is reproduced by a 30-year ERA5 climatology, consistent with jet-exit forcing and enhanced boundary-layer coupling over land. Conditions favorable for barotropic instability using the Rayleigh–Kuo criterion, were present over most of the period. A qualitative barotropic conversion proxy, computed from the eddy momentum covariance $⟨u^{\prime }{v}^{\prime }⟩$, shows positive values in the lower troposphere at Guanacaste and in the layer 850–700 hPa at San Andrés, suggesting mean-to-eddy momentum transfer, whereas the signal at Limón is weaker. Together, these results provide a physically consistent view of EW–CLLJ interactions across the IAS; therefore, a schematic of those mechanisms is proposed here. The results highlight the need for high-resolution modeling and full energy-budget analyses. Full article

Navío Quebrado Lagoon is a shallow coastal waterbody connected to the Caribbean Sea through an inlet, and it lies within Colombia’s protected-area system, specifically, the Los Flamencos Flora and Fauna Sanctuary. In this work we set up the Environmental Fluid Dynamics Code Plus (EFDC+) model to examine salinity behavior across 2024, combining field measurements with hydrological, meteorological, and tidal datasets obtained from national monitoring agencies. Model calibration used RMSE, the Nash–Sutcliffe efficiency (NSE), and R², and the fit was consistent for both water levels and salinity. To isolate the role of lagoon–sea connectivity, we compared a reference run (real inlet dynamics) against three scenarios: (E1) the inlet kept permanently open, (E2) the inlet kept permanently closed, and (E3) a second inlet kept permanently open while the original inlet maintained its observed opening/closure behavior. Model results show that under the reference condition, salinity presented strong spatial and seasonal changes, with 164 consecutive days of critical hypersalinity events, with an annual range of 0 to 200 ppt. Scenarios E1 and E3 produced more favorable conditions by keeping lagoon salinity within 0–66.9 ppt and 0–44.5 ppt, respectively. In contrast, E2 substantially altered hydrologic conditions and significantly reduced lagoon water volume and salinity variability. Full article

The high demand for conventional ingredients used in the formulation of rabbit diets has increased competition, resulting in higher costs. Tropical forage plants with high nutritional content can provide relief for this pressing issue, as well as offer potential health benefits to the animal, which would ultimately lead to a quality product. A review of 33 studies on Trichanthera gigantea (T. gigantea), Morus alba (M. alba, MA), Leucaena leucocephala (L. leucocephala, LL), Gliricidia sepium (G. sepium) and Moringa oleifera (M. oleifera) and their effect on rabbits spanning 1999 to 2026 was conducted. This review demonstrated that alternative tropical fodder trees found in the Caribbean have the potential to enhance performance, the oxidative status of sera and meat, carcass traits, blood and meat biochemistry indicators and digestibility. On the contrary, most of these plants contain anti-nutrients that exert negative effects on growing rabbits and their health. The evidence revealed in this review shows that various inclusion levels of the forages can improve rabbit meat production, thereby lowering ingredient costs and providing consumers with a quality protein option. Therefore, the incorporation of tropical forages in rabbit diets is recommended. Full article

Haiti is a Caribbean country of about 11 million people with a high burden of mosquito-transmitted disease and limited vector control, thereby making effective operational mosquito control of high importance. Previous studies have examined vector-borne disease burden and insecticide resistance markers in Haitian Aedes and Anopheles mosquitoes, but not Culex species. In this study, we examined collections of Culex quinquefasciatus from 12 locations in northern and southern Haiti for the presence of markers of insecticide resistance (using a variety of target-site mutations and biochemical assays) and pathogens (using a deep-sequencing microbiome workflow). The metagenomic analysis identified Wolbachia, Rhabdoviridae, and Plasmodium infections in all sample pools at relatively high levels, along with less frequent detections of other potential pathogens. Insecticide resistance marker examination identified variable frequencies of knockdown resistance and acetylcholinesterase resistance mutations, as well as variation in resistance-associated enzymatic activities in these populations. These findings indicate that insecticide resistance to pyrethroid and organophosphate insecticides is likely. Although there was variation among Culex mosquito populations and no clear activity pattern, enzymatic activity was significantly higher at the southern sites than at the northern sites. Similar findings in Cx. quinquefasciatus populations in other locations in the Americas strongly suggest that vector control with pyrethroid and organophosphate adulticides may be of limited efficacy. Full article

The recurrent influx of pelagic Sargassum spp. along Caribbean coastlines poses a significant environmental challenge while offering potential as a resource-recovery agricultural input. However, agricultural reuse of Sargassum biomass raises concerns regarding salinity and trace-metal distribution within the soil–plant–food continuum. This study evaluated the short-term elemental response to a Sargassum-Based Liquid Biofertilizer (SBLB) produced via controlled anaerobic fermentation, using tomato (Solanum lycopersicum L.) grown under greenhouse conditions. Raw biomass, fermented biofertilizer, irrigation water, soils, vegetative tissues, and fruits were chemically characterized. Elemental concentrations were quantified by ICP–OES and ICP-MS and treatment effects were analyzed using one-way and two-way ANOVA (p < 0.05). Anaerobic fermentation resulted in lower measured concentrations of sodium, arsenic, and selected trace elements in the liquid fraction relative to raw biomass. SBLB application increased soil macronutrient availability (N, P, K, Ca, Mg), while soil trace-metal concentrations remained within international reference ranges during the experimental period. Metals of concern (As, Cd, Pb, Ni, Cr) showed no detectable short-term enrichment in soils, vegetative tissues, or fruits relative to controls. In tomato fruits, arsenic, cadmium, and lead were below the limit of quantification across all treatments. Within the experimental timeframe, SBLB application was not associated with detectable trace-element accumulation in the soil–plant system. Long-term field studies and detailed soil physicochemical characterization are required to evaluate cumulative effects under repeated applications. Full article

Light availability drives Stevia rebaudiana productivity, yet how incident radiation interacts with genotype and site under tropical field conditions remains unclear. We evaluated four genotypes (L020, L102, L082, and ‘Morita II’) across three Caribbean locations in Colombia under two contrasting light levels (600 vs. 1800 μmol photons m⁻² s⁻¹) using a split-plot randomised complete block design with four replicates. Incident photosynthetic photon flux density (PPFD) was logged and, at 85 days after transplanting (DAT), net CO₂ assimilation, stomatal conductance, transpiration, and intercellular CO₂ concentration were measured alongside light-adapted chlorophyll fluorescence parameters, including the effective quantum yield of photosystem II (ΦPSII), the maximum efficiency of PSII in the light (Fv′/Fm′), photochemical quenching (qP), and electron transport rate (ETR); biomass and leaf yield were quantified at harvest. Data were analysed using factorial analysis of variance (ANOVA) and complementary multivariate approaches, including Pearson correlation analysis and principal component analysis (PCA). Radiation responses were strongly site-dependent: under 1800 μmol photons m⁻² s⁻¹, net CO₂ assimilation increased by 90.2% at El Carmen de Bolívar and 21.5% at Polonuevo but decreased by 36.4% at Montería. Leaf yield was highest in El Carmen de Bolívar (1951.46 ± 182.03 kg ha⁻¹), followed by Montería (1510.94 ± 173.75 kg ha⁻¹) and Polonuevo (576.31 ± 42.36 kg ha⁻¹). Genotype rankings shifted with environment and radiation, with L102 reaching 3256.25 ± 126.39 kg ha⁻¹ under direct radiation in El Carmen de Bolívar and ‘Morita II’ showing strong responsiveness in Montería. These results demonstrate that photosynthetic plasticity and leaf yield in S. rebaudiana depend on genotype × radiation × environment interactions, supporting location-tailored radiation management combined with targeted genotype deployment. Full article

The COVID-19 pandemic introduced an additional major stressor for families in the Caribbean, a region already shaped by environmental risk and socioeconomic vulnerability. This study examined changes in family resilience across pandemic phases among English-speaking Caribbean populations, drawing on Walsh’s family resilience framework, which emphasizes belief systems, organizational processes, and communication. Using a convergent parallel mixed methods design, quantitative and qualitative data were integrated from two studies conducted before and during pandemic restrictions and after restrictions were lifted. Survey data were collected from 198 families across English-speaking Caribbean nations, and in-depth interviews were conducted with 31 families from Grenada, Jamaica, and Trinidad. Quantitative analyses indicated a significant decline in family resilience during periods of heightened restrictions, followed by a return to pre-pandemic levels. Qualitative findings identified faith, family connectedness, communication, resourcefulness, and a positive outlook as key processes supporting adaptation during the crisis. Overall, results suggest that while family resilience at the population level was strained during the pandemic, it demonstrated recovery over time. Policies and interventions that strengthen communication supports and community- and faith-based resources may enhance family resilience and preparedness for future public health and environmental disruptions in the Caribbean. Full article

Through theorists like M. Jacqui Alexander, Édouard Glissant, Saidiya Hartman, Carolyn Cooper, and Michelle Wright, this project reconsiders the “vulgarity” attributed to Caribbean musical genres, like dancehall, dembow, and reguetón, as a pedagogical practice: an embodied, sensorial way of knowing that challenges colonial and racialized modes of aesthetics, morality, and order. Through an examination of Vybz Kartel’s “Fever,” Tokischa’s “Sistema de Patio,” and Bad Bunny’s “El Apagón,” I examine how sound, image, and movement converge to create what Alexander calls “pedagogies,” which simultaneously disturb and instruct. These pedagogies of the vulgar illuminate the ongoing impact of colonialism and plantation slavery in the Caribbean, particularly the gendered extraction of labor and capital that continues to shape daily life. In this context, vulgarity is not simply performed but inverted, prompting us to ask what is truly vulgar: Caribbean music and dance, or the systemic violence of Western modernity? These pedagogies foreground the paradoxical beauty of violence and survival, revealing how Caribbean peoples reconfigure “vulgarity” to craft pleasure and freedom amidst constraint. Embracing Michelle Wright’s concept of “epiphenomenal time,” this study invites readers to watch, listen, and feel, reminding us that the pedagogy of the vulgar must be embodied to be understood. Full article

Fetal growth restriction (FGR), a condition in which the fetus fails to achieve its growth and developmental potential, affects 5% to 10% of pregnancies and is associated with high rates of perinatal morbidity and mortality. There is currently insufficient high-quality evidence to define the optimal approach for diagnosing fetal growth restriction. In 2016, with the aim of standardizing clinical practice and enabling comparability across scientific studies, an expert opinion-based consensus was published. This document proposed unified terminology and clear diagnostic criteria for early- and late-onset fetal growth restriction (FGR). Because no effective treatment is available, careful assessment of fetal well-being and appropriate timing of delivery are the main tools for managing these fetuses. This decision should be based on gestational age and the severity of abnormalities identified on fetal surveillance tests, balancing the risks of prematurity against the risks of severe permanent sequelae or fetal death. The objective of this update is to analyze the most recent evidence on when and how to deliver pregnancies complicated by fetal growth restriction, emphasizing that specific abnormalities on fetal surveillance examinations warrant delivery at different gestational ages. To this end, a literature search of the PubMed/Medline and Latin America and the Caribbean Literature on Health Sciences (LILACS) databases was conducted using the terms fetal growth restriction, management, and delivery over the past ten years. Results were grouped into gestational age at delivery, mode of delivery, and methods of labor induction. The main fetal surveillance abnormalities prompting delivery in each gestational-age range were discussed, leading to the development of management flowcharts. Despite the lack of consensus in the literature and the limited number of randomized clinical trials guiding clinical decisions in FGR, the available evidence was summarized to assist clinicians in managing pregnancies complicated by FGR. It should be emphasized that there are few randomized clinical trials to guide management decisions in FGR. Full article

Warfarin is one of the most used oral anticoagulants, even after the arrival of non-vitamin K oral anticoagulants. Warfarin has been implicated in approximately one-third of emergency hospitalizations for adverse drug events among older adults in national U.S. data. Warfarin dose has been shown to vary between patients with up to 10 times the standard dose. This variability is due to multiple factors such as age, gender, diet, body size, co-medications, and the genetic background of the patient, where the genetic background accounts for 50% of warfarin dose variability among Europeans. Sadly, these findings do not apply to Caribbean Hispanic populations such as Puerto Ricans due to them having an admixed genetic profile. In the field of pharmacogenomics (PGx), the utility of machine learning (ML) has been used to predict individual drug responses by analyzing complex genetic and clinical data, which helps personalize medicine by tailoring treatments to a patient’s genetic makeup. Inclusion of ethno-specific variants has demonstrated improvement on the application of ML to a specific population. This study compares eight ML methods to predict warfarin sensitivity in Puerto Rican Caribbean Hispanics. This study is a secondary analysis of genetic and clinical data from 217 Puerto Rican patients treated with warfarin for thromboembolic disorders. After quality control filtering and exclusion of participant records with incomplete genetic and clinical data, 146 participants are retained for analysis. Data are divided into 65% and 35% to be used as training and test sets. Model performance is determined by comparing the precision and accuracy metrics, computed through the corresponding confusion matrixes. A gradient boosting classifier (GDB) achieves the highest overall accuracy (0.7500) and weighted precision of (0.7642); however, sensitivity for detecting warfarin-sensitive patients remains low. Feature importance analysis suggests that rs202201137 could contribute to model predictions, although overall detection of warfarin-sensitive individuals remains limited. Full article

Globally, diverse agricultural production strategies have been implemented to address the impacts of climate change, with sustainable farming models emerging as key approaches, particularly in regions affected by environmental degradation. Latin America is especially vulnerable due to its strong dependence on agriculture, pressure on natural resources, and persistent socioeconomic inequalities in rural areas. This study presents a review of sustainable agricultural practices, with particular attention to evidence from Latin America on sustainable agricultural practices as effective strategies for climate change adaptation and mitigation, natural resource conservation, and food security enhancement. Special emphasis is placed on the role of the bioeconomy and the integration of traditional knowledge with modern agricultural management, highlighting their combined contribution to agroecosystem resilience. The review critically examines how sustainable agricultural practices influence soil health, agroecosystem resilience, and the long-term sustainability of agricultural production within a circular economy framework. The findings indicate that practices such as no-till farming, crop rotation, organic fertilization, and integrated soil management significantly improve soil structure, nutrient retention, organic matter content, and soil biodiversity. These practices also reduce soil degradation, enhance resource-use efficiency, and promote carbon sequestration, thereby contributing directly to climate change mitigation. Overall, the results underscore the importance of holistic approaches that integrate traditional practices with technological innovations and highlight the need for further applied research across diverse environmental and socioeconomic contexts, particularly to address adoption barriers among smallholder farmers and to optimize sustainable agricultural strategies at local and regional scales. Full article

Nature-based tourism (NBT) is increasingly promoted as a means to contribute to conservation efforts. However, there is limited understanding of the relationship between environmental education and awareness and conservation attitudes and practices in this form of tourism that centers on green spaces. This study, therefore, aimed to explore this relationship using data from tourism operators and local communities in the Mexican Caribbean and provide useful insights for environmental sustainability in tourism destinations that depend on nature as a critical resource. The study employed a triangulation approach, which involved examination of two sets of data: firstly, household-level survey information from local communities participating in nature-based tourism; and secondly, data from semi-structured in-depth interviews with tour companies operating within the Mexican Caribbean, as well as focus group discussions with key informants including academicians, public-sector stakeholders and other opinion leaders in the tourism industry. Household surveys determined associations between potential predictor variables (environmental education and awareness, local community involvement, costs and benefits distribution) and conservation perspectives and practices in nature-based tourism. Semi-structured interviews and focus group discussions explored participants’ attitudes, experiences and views on environmental education and awareness, nature-based tourism, attitudes and practices towards conservation. Findings demonstrated that direct benefits from nature-based tourism are significant, but do not guarantee positive conservation attitudes and practices among the local communities. Other factors (indirect benefits), such as environmental education and awareness, could be more effective in achieving environmental sustainability and quality in nature-based tourism. It was also found that several tourism operators lack formal environmental education and awareness programs. The study recommends that the entire cycle of using natural resources for tourism purposes and tourists’ interaction with nature be anchored in adequate environmental education and awareness. This research contributes to valuable insights into debates, practices and policy developments related to nature-based tourism as a mechanism for environmental sustainability in biosphere reserves and tourism destinations. Full article

Coastal ecosystems of the tropical Atlantic and the Mexican Caribbean have experienced recurrent massive influxes of pelagic brown macroalgae, Sargassum natans and Sargassum fluitans, generating severe environmental, social, and economic impacts. While the accumulation of this biomass poses a significant waste management challenge, it also represents an underexploited renewable resource aligned with circular economy and sustainability principles. This study investigated the valorisation of Sargassum spp. through comprehensive physicochemical characterisation and multiple value-added applications. The biomass collected in Tulum, Quintana Roo, Mexico, was analysed to determine its chemical composition, including lignin, holocellulose, α-cellulose, ash, and moisture content, using standardised methods of the Technical Association of the Pulp and Paper Industry (TAPPI). For mechanical testing, methods from the American Society for Testing and Materials (ASTM) were used. The biomass was subjected to controlled pretreatment and thermochemical conversion processes. Evaluated valorisation pathways included: (1) taxonomic identification and physicochemical characterisation, (2) polymer composites, (3) reinforcement in construction materials such as unfired clay bricks, and (4) biochar and activated carbon production for contaminant adsorption. The results demonstrated that Sargassum spp. biomass can be transformed from an environmental nuisance into a multifunctional, high-value biomaterial, providing scalable solutions that mitigate waste disposal challenges and contribute to climate and resource sustainability. Full article

In the San Diego–Tijuana border region, characterized by human mobility dynamics, institutional vulnerability, and inequalities, experiences of financial exclusion among Latin American migrants are deeply intertwined. This study draws on in-depth interviews with 14 migrants from Central America, South America, and the Caribbean, including both men and women. It analyzes factors such as undocumented status, institutional mistrust, cultural barriers, and regulatory requirements that shape access to financial services. In contexts of exclusion, migrants resort to social support networks, informal strategies, and emerging digital options such as fintech. The study adopts a qualitative design, using an analysis based on emerging categories to construct analytical dimensions grounded in participants’ trajectories and voices. The findings show that financial inclusion does not depend solely on access to services, but also on recognizing the lived experiences, emotions, and everyday obstacles faced by migrants. Far from being passive recipients, migrants play an active role in building responses to exclusion. The study concludes that making these practices visible and designing policies grounded in migrants’ realities are essential steps toward a more just and accessible financial system. Full article