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Benzamide Derivatives Targeting the Cell Division Protein FtsZ: Modifications of the Linker and the Benzodioxane Scaffold and Their Effects on Antimicrobial Activity
- Valentina Straniero,
- Lorenzo Suigo,
- Andrea Casiraghi,
- Victor Sebastián-Pérez,
- Martina Hrast,
- Carlo Zanotto,
- Irena Zdovc,
- Carlo De Giuli Morghen,
- Antonia Radaelli and
- Ermanno Valoti
Filamentous temperature-sensitive Z (FtsZ) is a prokaryotic protein with an essential role in the bacterial cell division process. It is widely conserved and expressed in both Gram-positive and Gram-negative strains. In the last decade, several resea...