Special Issue "Viral Sequence Diversity and Correlations to Disease"

A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Human Virology and Viral Diseases".

Deadline for manuscript submissions: 1 November 2021.

Special Issue Editor

Prof. Dr. Brian Wigdahl
E-Mail Website
Guest Editor
Drexel University College of Medicine, Department of Microbiology and Immunology, Philadelphia, United States
Interests: Immunopathogenesis and neuropathogenesis of HIV-1 and HTLV-I infection; transcriptional regulation of retroviral expression; development of microbicidal agents

Special Issue Information

Dear colleagues,

The replication of human DNA and RNA viruses, as well as retroviruses, occurs in a highly regulated manner that is sequentially and coordinately regulated to guide the expression of early and late genes prior to, during, and after the production of new progeny genomes, as guided by specific nucleic acid polymerases encoded by each virus. In addition, the genetic complexity of these three viral families is altered during their respective life cycles, as well as at their associated pathogenic endpoints and disease outcomes associated with their interactions with their human host and also in the many animal models that have been used over the years in order to develop approaches to diagnose, prevent, and treat life threatening diseases caused by these three viral families. Particularly relevant to this Special Issue of Viruses is the impact of genetic variation and viral diversity with respect to the complexity of these medically important families of viruses in relation to the viral genome architecture. In addition, the relationship to virus replication, pathogenesis, and disease with respect to impact on diagnosis, prevention, and treatment is also of interest. Reviews and primary papers will be entertained in areas specifically relating to but not limited to the (1) structure and function of the viral genome; (2) viral genome complexity  viral genetic markers; (3) development and disease severity assessment; (4) pathogenic emergence “tomorrow’s pathogen”; (5) genetic variation as it relates to vaccine development; (6) intraspecies viral jumping; (7) development of drug resistance; (8) organ- and cell-specific compartmentalization of viral variants; (9) course of acute and/or chronic infection; (10) bioinformatic approaches to facilitate studies concerning any of the preceding areas of investigation.

Prof. Dr. Brian Wigdahl
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • viral genetic variation
  • pathogenesis and disease severity
  • human immunodeficiency virus
  • influenza virus
  • coronaviruses

Published Papers

This special issue is now open for submission.
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