The Role of Adjuvants in Viral Vaccines and Vaccination
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "Viral Immunology, Vaccines, and Antivirals".
Deadline for manuscript submissions: 31 July 2026 | Viewed by 10
Special Issue Editor
Interests: influenza; vaccines; serology; clinical trials
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Not too long ago, infectious diseases have claimed millions of lives each year worldwide. In 1918, the Spanish flu alone killed 50 million people, after more than four years of World War I. The rapid advancement of medical science, mostly consisting of the development of novel antimicrobial agents, changed that picture greatly. In addition to modern antimicrobials, the greatest difference was made by the development of vaccines. However, developing safe and effective agents is extremely challenging, especially in the case of virus vaccines. One method of improving vaccine efficacy without increasing the amount of antigen used is by utilizing adjuvants. Therefore, in recent decades, several forms of vaccine adjuvants have been developed. This process was rapidly facilitated by the appearance of highly pathogenic avian influenza, which was extremely difficult to immunize against. During the early decades of adjuvanted vaccines, most of them used some form of aluminum salt. However, more recently, a variety of novel adjuvants have been developed. As a result, five new vaccine adjuvants have been approved for use by the FDA since 2009, with several more under development. This Special Issue will feature both review articles that summarize past achievements and original research papers that present novel findings on vaccine adjuvants.
We invite contributions covering, but not limited to, the following subtopics:
- Mechanisms of adjuvant and vaccine efficacy;
- Safety and reactogenicity of novel adjuvants;
- Innovative adjuvants for next-generation vaccines;
- Future directions of viral vaccine adjuvant development.
Dr. Zoltan Vajo
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Viruses is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- aluminum hydroxide
- oil-in-water emulsion adjuvants
- TLR agonists
- combination adjuvants
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