Neurotropic Viral Pathogens
A special issue of Viruses (ISSN 1999-4915). This special issue belongs to the section "General Virology".
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 17094
Special Issue Editors
Interests: CNS infection
Interests: neuroviral infections
Special Issue Information
Dear Colleagues,
This Special Issue of Viruses focuses on viral infections of the nervous system (NS) both at the molecular and systems level, including models of viral-induced human neurological disease. The NS is protected against viral infection by several layers of anatomical and physiological barriers. However, most of the human population has been infected with persistent viruses that either establish infection in the NS or can gain access to the NS upon reactivation, causing a wide array of neurological problems ranging from mild symptoms to life-threatening conditions. Moreover, emerging virus infections represent a threat to the NS either by direct transmission to the neural tissue or by triggering inflammation or degeneration of the NS, as we experienced in the Zika virus outbreak and the COVID-19 pandemic. Therefore, it is of great importance to understand the mechanisms underlying viruses’ abilities to access to the NS, establish infection and spread in the neural circuits. Additionally, we need to identify the mechanisms by which these viruses evade immunological attack and how the immune system responds to infection and eliminates these invaders while limiting the severity of immune-mediated neurologic diseases. Greater insight into these questions through discovery-based research will inevitably allow for the development of better therapeutic strategies against latent, chronic or emerging neuroviruses.
Prof. Dr. Thomas E. Lane
Dr. Orkide Ö. Koyuncu
Prof. Dr. Michael J. Buchmeier
Guest Editors
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