Special Issue "Influence of Helminths on Concomitant Diseases and Infections and Vaccination Efficacy"
A special issue of Tropical Medicine and Infectious Disease (ISSN 2414-6366).
Deadline for manuscript submissions: 10 July 2021.
Interests: NTDs; Filarial infections (mouse and human); Podoconiosis; Immunomodulation by helminths and effects on concomitant infections and diseases
2. German Centre for Infection Research (DZIF), Partner Site, Munich, Germany
Interests: filarial infections; drug discovery; filarial immunomodulation; eosinophil ETosis
Helminths are prevalent worldwide, and it is estimated that more than 1 billion people are infected with these parasitic worms. It is known that helminth infections dampen and modulate host immune responses via the induction of regulatory B and T cell subsets and Th2 cell populations and the suppression of Th1 and proinflammatory cell populations and their cytokine and chemokine secretion. Although this immunomodulation leads to an asymptomatic clinical picture in most infected people, it is suggested that helminth-driven immune regulation increases susceptibility to and worsens disease course of concomitant bacterial, viral, and parasitic infections and lowers vaccination efficacy. On the other hand, helminths have been shown to protect against autoimmune and metabolic diseases. However, knowledge about helminth-driven immunological mechanisms and their influence on unrelated infections and diseases and vaccination programs is lacking. Thus, further research is urgently needed to decipher the risk factors as well as the potential of helminths.
This Special Issue aims to address open questions as to how helminths influence concomitant infections and diseases and vaccination efficacy, which is an important issue in meeting the challenges of the Sustainable Development Goals (SDGs) put forward by the United Nations, particularly Goal 3, "Good Health and Well-Being". Manuscript topics may include basic research questions using preclinical animal models as well as clinical, observational, and interventional studies.
Dr. Manuel Ritter
Dr. Inge Kroidl
Prof. Dr. Clarissa Prazeres da Costa
Prof. Dr. Marc Hübner
Dr. Gnatoulma Katawa
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Tropical Medicine and Infectious Disease is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- concomitant viral, bacterial and parasitic infections
- neglected tropical diseases
- autoimmune and metabolic diseases
- immunomodulation, immune regulation
- vaccination efficacy
- sexually transmitted diseases (STDs)