Advances in MRI Detection and Characterization of Neurodegenerative Diseases
A Special Issue of Tomography (ISSN 2379-139X) belonging to the section "Neuroimaging".
Deadline for manuscript submissions: 31 January 2027 | Viewed by 509
Editors
Interests: MRI; myelin; glymphatic; neurodegenerative disorders; epilepsy; brain network; diffusion MRI; functional MRI
Interests: MRI; glymphatic; sleep; arousal; neurodegenerative disorders; cerebrospinal fluid; women’s health; systemic physiology; diffusion MRI; functional MRI
Special Issue Information
Dear Colleagues,
Neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and Multiple Sclerosis, represent a growing global health challenge. Early detection and precise characterization of these disorders are essential for improving early diagnosis, monitoring clinical and radiological progression, risk stratification, and evaluating therapeutic interventions. MRI plays a central role in these efforts by offering non‑invasive insights into structural, microstructural, and functional changes in the brain. Beyond conventional clinical imaging, advanced quantitative MRI techniques such as diffusion imaging, relaxometry, susceptibility mapping, and quantitative multiparametric approaches enable higher sensitivity for the detection of subtle and early pathological alterations that often precede clinical symptoms.
This Special Issue aims to highlight the latest developments in MRI-based detection and characterization of neurodegenerative diseases. We invite contributions that explore novel imaging characteristics, methodological innovations, and integrative approaches combining multimodal imaging, computational modeling, or machine learning. Topics may include, but are not limited to, myelin imaging, interstitial fluid dynamics, microvascular integrity, and brain network (covariance) analysis. Methods integrated with systemic physiology are also welcomed, shedding light on brain–body interactions. By integrating research on MRI techniques for neurodegeneration, this collection seeks to accelerate the translation of imaging biomarkers into clinical practice, enhancing early diagnosis, patient stratification, and monitoring of disease progression, ultimately contributing to better outcomes for individuals affected by neurodegenerative disorders.
Dr. Gerhard Drenthen
Dr. Merel van der Thiel
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Tomography is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- MRI
- myelin
- glymphatic
- systemic physiology
- sleep
- neurodegenerative disorders
- Alzheimer’s disease
- Parkinson’s disease
- dementia
- multiple sclerosis
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