Special Issue "Enantiocontrolled Synthesis of Fluoro-Organic Compounds"

A special issue of Symmetry (ISSN 2073-8994).

Deadline for manuscript submissions: closed (9 November 2019).

Special Issue Editor

Prof. Renzo Ruzziconi
Guest Editor
Dipartimento di Chimica, Biologia e Biotecnologie Università di Perugia via Elce di Sotto 8 I-06123 – PERUGIA / Italy
Interests: Reaction mechanism studies; Syntheses with polar organometallic reagents; mono-electronic metal oxidant-promoted radical reactions; synthesis of pharmacologically active fluorinated compounds; ransition metal catalysed stereoselective reactions.

Special Issue Information

Dear Colleagues,

The unique properties of the fluorine atom and carbon–fluorine bonds have made the study of fluorinated organic chemicals a major research topic in both academia and industrial laboratories. They find important applications in the design of new pharmaceuticals, agrochemicals, polymers, materials, surfactants or radiochemicals, among other. One of the most fascinating aspects of organofluorine chemistry is the asymmetric synthesis of fluorinated molecules. This is a very challenging topic with great potential in numerous areas. Asymmetric synthesis is now a mature area of organic chemistry; however, asymmetric fluorination and perfluoroalkylation are developing relatively slowly.

The aim of this Special Issue is to highlight and overview the most advanced technologies, including the use of chiral building blocks, chiral auxiliaries, organometallic catalysis, enzymatic catalysis and organocatalysis, to introduce fluorine and fluoroalkyl groups into organic molecules in a stereoselective way. Moreover, the development of the most advanced techniques to assign the correct absolute configuration to stereogenic carbon-bonding fluorine atoms or fluoroalkyl groups will be taken into consideration.

Prof. Renzo Ruzziconi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Symmetry is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Stereoselective fluorination using chiral auxiliary
  • Organometal catalysed stereoselective fluorination
  • Organocatalytic stereoselective fluorination
  • enzymatic stereoselective fluorination
  • stereoselective fluoroalkylation
  • chiroptical properties of fluorinated stereogenic carbons
  • new reagents for stereoselective fluorination

Published Papers

There is no accepted submissions to this special issue at this moment.
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