Special Issue "Recent Advances in the Identification of Minor Constituents in Plants and Microorganisms"
Deadline for manuscript submissions: closed (10 April 2022) | Viewed by 190
Interests: traditional Chinese medicines; natural products chemistry; chemical biology; marine drugs; natural products-based drug discovery
In the last century, natural products (NPs) have acquired a well-known reputation for drug discovery due to their abundant chemical diversity, enormous structural complexity and drug-like properties. Plants, especially those traditional medicinal herbs, are considered to be vast resources with great potential in searching for novel NPs and drug leads own to their explicit therapeutic effects throughout human history. Nevertheless, NPs are confronted with some challenges, including technical shortages for isolation and identification of minor constituents with novel scaffolds, insufficient amounts of bioactive NPs, and inefficient bio-active screening. As one of the world’s largest and easiest life-forms, microorganisms (such as bacteria and fungi), which emerged much earlier than plants on the Earth, are believed to produce a huge quantity of original NPs, many of which applied to the development of pharmaceutical, food and cosmetic industries. In recent decades, NPs derived from plants and microorganisms have not only inspired scientists to explore NPs’ diversity and novelty in a whole new scale, but also provided opportunities for the development of NPs-based front-line drug. Moreover, the rapid progress in the understanding of NPs’ biosynthesis in plants and microorganisms together with their potential therapeutic mechanisms could create a new era for the exploration of NPs in the future.
Therefore, it is my pleasure to invite you to contribute your research article, communication, or review in this Special Issue dedicated to techniques of Identification of Minor Constituents in Plants and Microorganisms.
Dr. Yongbo Xue
Dr. Xiangdong Su
Manuscript Submission Information
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- Natural products
- Minor constituents
- Novel scaffolds
- Structural identification
- Drug leads
- Bioactive NPs
- Therapeutic mechanisms