Dear Colleagues,

The collection of whole blood samples, known as dried blood spot (DBS), dates back to the early 1960s at the beginning in new-born screening for inherited metabolic disorders. DBS is an innovative method offers a simple and practical means of blood collection – making it an attractive alternative to traditional methods. Moreover, the DBS technique offers several advantages over conventional for different biological material such as blood, plasma, or serum. This method is microinvasive - collected through finger or heel pricks. Sample transfer and storage are easier because the specimen is non-breakable and not required to be frozen. Volume of blood required is smaller – less than 50 µL. Blood samples spotted on a DBS card/paper can be stored for several months or years at room temperature. Due to these advantages, DBS is mainly used in clinical and forensic toxicology, drug screening, therapeutic drug monitoring and neonatal screening. This Special Issue looks at these and other aspects of current research into the innovative Dried Blood Spot methodology.

Prof. Dr. Renata Wietecha-Posluszny
Guest Editor

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• Dried Blood Spot
• Biological and non-biological samples
• Clinical and Toxicological analysis
• Forensic chemistry
• Separation and spectroscopy methods
• Calibration methods
• Chemometrics
• Factor selection
• Machine learning