Special Issue "Separations and Analysis of Proteins in Biological Samples"

A special issue of Separations (ISSN 2297-8739).

Deadline for manuscript submissions: 25 October 2021.

Special Issue Editor

Prof. Dr. Ivan Mikšík
Guest Editor
Institute of Physiology, Academy of Sciences of the Czech Republic, Prague 4, Czech Republic
Interests: applications of analytical chemistry (capillary electrophoresis, high performance column and mass spectrometry) to the analysis of biological (physiological) functions of the organism, i.e., mainly proteins but not only

Special Issue Information

Dear Colleagues,

Analysis of proteins in biological samples is an increasingly evolving and desirable method for studying organisms, their functions, and development. The development of these analyses is made possible by the development of advanced analytical methods. It mainly includes the use of modern methods of mass spectrometry in conjunction with separation techniques. An integral part of this research is the use of appropriate methods for sample preparation that allow targeted analysis (e.g., biomarkers). Thus, the methods may include both targeted analysis and screening studies. It should be borne in mind that proteins are a remarkably diverse group of substances that can differ significantly in their properties. Therefore, the problem of protein analysis in biological samples is a kind of art—analytical art.

The presented Special Issue should include both well-arranged articles providing an overview of the current development of methods and procedures of analyses in real biological samples, as well as experimental works dealing with new procedures and approaches applied in specific analytical problems. Papers on new techniques suitable for protein analysis are also welcome. Of course, the scope of this volume is not limited to the analysis of “pure” proteins but also includes their modifications, such as glycosylation, glycation, phosphorylation, and many others.

The aim of this Special Issue should be to provide a general overview of modern methods used to analyze proteins in biological samples, but also to outline the current trends in these methods, to acquaint the scientific community with modern procedures and approaches to real proteomic analysis, whether targeted or screening studies.

Prof. Dr. Ivan Mikšík
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Separations is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • protein analysis
  • sample preparation
  • target analysis
  • glycoprotein
  • peptide analysis
  • mass spectrometry
  • biological sample
  • chromatography

Published Papers

This special issue is now open for submission.
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