Exploratory Research of Metabolomics Methods

Dear Colleagues,

While metabolomics can be a powerful tool in studying complex biological processes as it is the closest representation of phenotype, it still lags behind other -omics with respect to well established SOPs and comprehensive data analysis tools. Resources for reliable compound identification such as spectral libraries are limited in size and scope which further confounds the high-throughput structural elucidation of metabolites. Study design, accurate and robust methods for statistical evaluation of large-scale data, the handling of missing values, and harmonization tools for integrating genomics and metabolomics data to aid with microbiome research are just a few of the grand challenges in metabolomics. This Special Issue aims to focus on the best practices and protocols for both experimental and computational aspects of metabolomics, and in doing so we hope to showcase some of the great work by our fellow metabolomics scientists.

Dr. Maryam Goudarzi
Dr. Tytus Mak
Dr. Mohammad Alyamani
Guest Editors

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• broad metabolomics methods
• challenges in metabolomics methods
• lack of standardization
• comprehensive data tools
• lack of gold standards in dealing with 0s
• normalization techniques