Special Issue "Chemical Diversity and Anticancer Activity of Natural Compounds"

A special issue of Separations (ISSN 2297-8739). This special issue belongs to the section "Analysis of Natural Products and Pharmaceuticals".

Deadline for manuscript submissions: closed (5 April 2022) | Viewed by 301

Special Issue Editor

Dr. Biliana Nikolova
E-Mail Website
Guest Editor
Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria
Interests: anticancer drugs; electrochemotherapy; drug delivery systems

Special Issue Information

Dear Colleagues,

Recently, a number of products of natural origin have attracted worldwide research attention. The focus is on the search for bioactive substances for the development of new drugs, because of their relatively low toxicity and high bioactivity. Cancer is one of the leading causes of mortality, and logically, the main goal of the biological, pharmaceutical, and medical sciences is to increase the effectiveness of its treatment. The prolongation of life expectancy, improvement of life quality, and reduction in side effects after treatment are among the main aims of biomedical sciences. Therefore, it is important to find novel, effective, and less toxic compounds from natural sources to be used together with conventional chemotherapy.

While natural compounds are complex mixtures of components of various properties and activity, it is of great importance for them to be separated, analyzed in detail, and with a clear chemical structure in order to elucidate their possible antitumor properties.

On the other hand, the design and synthesis of novel derivatives of established cytostatic drugs bearing biologically active moieties proves the need for further investigation. The combination of nontoxic biological macromolecules that have antitumor activity with classic or newly synthesized anticancer drugs may be a step forward in the fight against socially significant diseases such as cancer.

The intersection of biological, chemical, and medical research will contribute to the development of new strategies for adequate disease treatment.

We would like to invite investigators to contribute original research articles that can stimulate continuing efforts to understand the health effects of natural, biologically active products alone or in combination with chemical substances in order to improve the health effects of therapies. Review articles are also welcome.

Dr. Biliana Nikolova
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Separations is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • anticancer effect
  • natural anticancer products
  • cytotoxicity
  • chemotherapy
  • cytostatic drugs

Published Papers

There is no accepted submissions to this special issue at this moment.
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