Special Issue "Reoviruses and the Interferon Response"
A special issue of Pathogens (ISSN 2076-0817).
Deadline for manuscript submissions: closed (15 September 2020) | Viewed by 2001
Interests: reovirus; oncolytic viruses; interferon
Special Issues, Collections and Topics in MDPI journals
The Orthoreovirus genus of the Reoviridae family encompasses a large group of viruses that infect not only humans but a large array of mammals, birds, and reptiles. They are also closely related to Aquareoviruses that are important fish pathogens. Although the classical mammalian reoviruses have been mostly studied in the past, there has been important progress in our understanding of all these viruses in the last decade. The development of reverse genetics for some of these viruses was certainly essential in recent progress. Furthermore, although mammalian reoviruses are generally considered as minor pathogens in humans, recent data suggest their involvement in chronic diseases such as celiac disease, while the emergence of new pathogenic strains remains possible. Finally, mammalian reoviruses are among a plethora of viruses presently under study as oncolytic agents against cancers of humans or animals. The importance of the interferon response, and the ability of a virus to control it, does not need to be proven. Not only is it involved in the pathogenicity of the infectious agent, but it can also affect its ability to infect given cell types, such as cancer cells.
In this Special Issue, we would like to invite the submission of original research or review manuscripts that cover these different aspects of the interactions between Orthoreovirus or Aquareovirus and the interferon response network. This also includes all aspects relating to pathogenesis, disease prevention, and applied virus use, such as oncolytic activity. We hope the manuscripts from this Special Issue will provide new insights into the biology of this fascinating group of viruses. I look forward to your contribution.
Prof. Dr. Guy Lemay
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Viral pathogenesis
- Viral oncolysis
- Viral genetics