Special Issue "Plant-Pathogen Interactions"

A special issue of Pathogens (ISSN 2076-0817).

Deadline for manuscript submissions: 31 October 2020.

Special Issue Editor

Dr. Hernan Garcia-Ruiz
Website
Guest Editor
Department of Plant Pathology, Nebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, NE 68583 USA
Interests: Plant-virus interactions, particularly antiviral RNA silencing, viral RNA replication and their interconnections

Special Issue Information

Dear Colleagues,

Plants interact with a diverse array of organisms, including insects, nematodes, microbes, and other plants. Plant–microbe interactions could result in disease or beneficial relationships. For any plant–microbe combination, the interaction could be incompatible or compatible. Plant pathogens, including bacteria, fungi, oomycetes, viruses, and nematodes, must evade or actively suppress plant defense responses. Understanding the molecular mechanisms of plant defense and microbe pathogenicity represents the basis for disease management, genetic engineering of disease resistance through gene editing, RNA silencing u other approaches. This Special Issue on plant–pathogen interactions is focused on recent advances in understanding the molecular and genetic basis of plant defense, pathogenicity or the establishment of beneficial relationships. Variation in plant or pathogen factors, computational modeling or methodologies that advance our understanding of plant–pathogen interactions are of interest. You are invited to submit primary research articles or reviews presenting recent advances.

Dr. Hernan Garcia-Ruiz
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Pathogenicity
  • Virulence
  • Effectors
  • Susceptibility genes
  • Resistance genes
  • Gene networks
  • Molecular determinants

Published Papers (1 paper)

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Research

Open AccessArticle
The 3′ Untranslated Region of a Plant Viral RNA Directs Efficient Cap-Independent Translation in Plant and Mammalian Systems
Pathogens 2019, 8(1), 28; https://doi.org/10.3390/pathogens8010028 - 28 Feb 2019
Cited by 2
Abstract
Many plant viral RNA genomes lack a 5′ cap, and instead are translated via a cap-independent translation element (CITE) in the 3′ untranslated region (UTR). The panicum mosaic virus-like CITE (PTE), found in many plant viral RNAs, binds and requires the cap-binding translation [...] Read more.
Many plant viral RNA genomes lack a 5′ cap, and instead are translated via a cap-independent translation element (CITE) in the 3′ untranslated region (UTR). The panicum mosaic virus-like CITE (PTE), found in many plant viral RNAs, binds and requires the cap-binding translation initiation factor eIF4E to facilitate translation. eIF4E is structurally conserved between plants and animals, so we tested cap-independent translation efficiency of PTEs of nine plant viruses in plant and mammalian systems. The PTE from thin paspalum asymptomatic virus (TPAV) facilitated efficient cap-independent translation in wheat germ extract, rabbit reticulocyte lysate, HeLa cell lysate, and in oat and mammalian (BHK) cells. Human eIF4E bound the TPAV PTE but not a PTE that did not stimulate cap-independent translation in mammalian extracts or cells. Selective 2′-hydroxyl acylation analyzed by primer extension (SHAPE) footprinting revealed that both human and wheat eIF4E protected the conserved guanosine (G)-rich domain in the TPAV PTE pseudoknot. The central G plays a key role, as it was found to be required for translation and protection from SHAPE modification by eIF4E. These results provide insight on how plant viruses gain access to the host’s translational machinery, an essential step in infection, and raise the possibility that similar PTE-like mechanisms may exist in mRNAs of mammals or their viruses. Full article
(This article belongs to the Special Issue Plant-Pathogen Interactions)
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