Metabolic Bone Diseases

A special issue of Osteology (ISSN 2673-4036).

Deadline for manuscript submissions: closed (30 June 2021) | Viewed by 699

Special Issue Editor


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Guest Editor
Centre for Metabolic Bone Diseases, University Hospitals Leuven, Leuven, Belgium

Special Issue Information

Dear Colleagues,

Osteoporosis is the most common bone disease, predisposing to fractures and posing a considerable disease burden in post-menopausal women and older men. Other metabolic bone diseases receive even less attention. Rickets (in growing children) and osteomalacia result from lack of calcium, vitamin D, or hypophosphatemia. These disorders have not been eliminated, as some believe; rather, their prevalence may be increasing. Rare genetic causes have shed light on the unique pathophysiology of calcium and phosphate mineral homeostasis. Rare bone diseases such as X-linked hypophosphatemia and hypophosphatasia are now treatable diseases, thanks to new therapeutic options. Osteogenesis imperfecta is another rapidly expanding field with increasingly recognized underlying genetic mutations. On the opposite side of the spectrum, insights into the pathophysiology of high-bone-mass disorders and sclerosing bone dysplasias has resulted in the identification of several therapeutic targets for osteoporosis, such as the inhibition of sclerostin and other Wnt signaling suppressors. The latest nosology on rare bone diseases encompasses no less than 461 conditions in 42 categories.

The present Special Issue aims to provide an overview of the state-of-the-art and provide examples of novel research directions in osteoporosis and other metabolic bone diseases, both in children and adults.

We invite all colleagues to submit manuscripts (research articles, case reports, and reviews) to this Special Issue. Submitted manuscripts may cover all aspects, ranging from pathophysiology and the diagnosis and treatment of osteoporosis, to other common and rare metabolic bone diseases and disorders of mineral metabolism.

Dr. Michaël R. Laurent
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Osteology is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • osteoporosis
  • metabolic bone diseases
  • osteomalacia
  • rickets
  • X-linked hypophosphatemia
  • rare bone diseases
  • hypophosphatasia
  • osteogenesis imperfecta
  • diagnosis
  • treatment
  • pathophysiology

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Published Papers

There is no accepted submissions to this special issue at this moment.
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