Special Issue "Nutrition and Cystic Fibrosis"

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: 20 May 2021.

Special Issue Editors

Prof. Dr. Shawn Somerset
Guest Editor
Faculty of Health, University of Canberra, Canberra, ACT 2617, Australia
Interests: chronic disease prevention; coronary heart disease; cystic fibrosis; community nutrition; marginalised communities; dietetics
Prof. Dr. Stephanie Van Biervliet
Guest Editor
Department of Paediatric Gastroenterology, Hepatology, and Nutrition, University Hospital Ghent, 9000 Ghent, Belgium
Interests: cystic fibrosis; gastroenterology; liver disease; inflammatory bowel disease; child health

Special Issue Information

Dear Colleagues,

Cystic fibrosis (CF) is an inherited disease with significant nutrition-related implications. The past few decades have seen substantial improvements in CF treatment, and consequently in life expectancy. Nutrition therapy has been integral to these improvements.

Historically, CF nutrition has focused on addressing nutritional deficit—a focus which continues. As the survival rate of people with CF has increased, there has been a corresponding increased prevalence of chronic conditions such as obesity, cardiovascular disease, diabetes and cancer, thus expanding the scope of nutrition treatment.

Just as nutrition has been a key factor in enhancing longevity in CF to date, it continues to have an integral role in meeting future challenges in the treatment of the complexities of this disease and its comorbidities.

Based on your insights and expertise in this field, we hope you will consider contributing either evidence-based original research or a critical review for this upcoming Special Issue.

Prof. Dr. Shawn Somerset
Prof. Dr. Stephanie Van Biervliet
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • cystic fibrosis
  • nutrition
  • diet
  • microbiota
  • nutrient absorption
  • treatment adherence
  • diabetes

Published Papers (1 paper)

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Open AccessArticle
Oral Nutritional Supplements in Adults with Cystic Fibrosis: Effects on Intake, Levels of Fat-Soluble Vitamins, and Bone Remodeling Biomarkers
Nutrients 2021, 13(2), 669; https://doi.org/10.3390/nu13020669 - 19 Feb 2021
Background: The use of oral nutritional supplements (ONS) is common practice in patients suffering from cystic fibrosis (CF). We aimed to describe the rate of ONS use to assess their contribution to dietary intake and to determine if they are associated with respiratory [...] Read more.
Background: The use of oral nutritional supplements (ONS) is common practice in patients suffering from cystic fibrosis (CF). We aimed to describe the rate of ONS use to assess their contribution to dietary intake and to determine if they are associated with respiratory status, body composition, muscle strength, bone mineral density (BMD), bone remodeling biomarkers, and plasmatic levels of vitamins. Methods: Cross-sectional study. Patients were clinically stable adults recruited from the CF unit. A 4-day prospective dietary questionnaire was conducted; in addition to respiratory variables, body composition, and BMD (through densitometry, DXA), muscle strength (JAMAR dynamometer), fat-soluble vitamins, and bone remodeling biomarkers (vitamins A, D, and E; osteocalcin, OC; undercarboxylated osteocalcin, ucOC; degradation of the C-terminal telopeptides of type I collagen, CTX; and receptor activator of nuclear factor-kappaB ligand, RANKL) were also evaluated. Results: The study included 59 subjects with CF (57.6% female, mean age 29.3 ± 9.4 years, and BMI 22.0 ± 3.6 kg/m2). In this study, 22% (13) patients were taking ONS and presented, compared with those not taking them, significantly more total and mild exacerbations and lower BMI; moreover, they showed a significantly higher total daily calorie intake in addition to a higher consumption of carbohydrates, proteins, and lipids per kg of body weight, omega-3 fatty acids, and vitamins A, D, and E. Vitamin E plasmatic levels were significantly higher in the group on ONS, as was the case with RANKL; finally, a lower rate of vitamin D deficiency was also found. Conclusions: ONS were used by patients with worse respiratory and nutritional statuses and their use was associated with a higher intake of macro- and micronutrients and with better plasmatic levels of fat-soluble vitamins. Full article
(This article belongs to the Special Issue Nutrition and Cystic Fibrosis)
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