Special Issue "The Benefits of Bioactive Compounds from Natural Resources and Relative Antioxidant and Health-Promoting Properties"

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: 30 September 2021.

Special Issue Editor

Dr. Dario Donno
E-Mail Website
Guest Editor

Special Issue Information

Dear Colleagues,

Despite the development of modern medicine against the increasing prevalence of several diseases, such as type 2 diabetes, obesity and its comorbidities, hepatic issues, and cardiovascular problems, primary healthcare needs in the world are related to medicinal plants, traditional agri-food products, and natural phytomedicines for cultural and historical reasons due to their health-promoting properties.

Underexploited or underutilized species, grown in seminatural conditions, or cultivated plants with traditional use in food and medicine, possess great health-promoting properties thanks to their bioactive compounds and antioxidant molecules. Secondary metabolites show specific health-promoting benefits and antioxidant effects in humans and animal models; analytical, clinical, epidemiological, and biological studies have demonstrated that a diet rich in foods and beverages derived from plants may reduce the risk of many diseases. Research on these plants is important to find innovative sources for natural nutraceuticals, antioxidants, and functional foods.

This Special Issue will collect recent high-quality research and review papers in the field of potential health-promoting plants and relative derived-products, evaluation of their potential benefits, and phytochemical characterization of the main bioactive compounds, in order to develop innovative health-promoting products with a high healthy value.

Dr. Dario Donno
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Antioxidant compounds
  • Underexploited plants
  • Phytochemicals
  • Health-promoting properties
  • Natural medicines
  • Traditional foods
  • Analytical strategies
  • Biological benefits

Published Papers (2 papers)

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Research

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Article
Can Cranberry Juice Protect against Rotenone-Induced Toxicity in Rats?
Nutrients 2021, 13(4), 1050; https://doi.org/10.3390/nu13041050 - 24 Mar 2021
Cited by 1 | Viewed by 890
Abstract
The high polyphenols content of cranberry accounts for its strong antioxidant activity underlying the beneficial health effects of this fruit. Rotenone (ROT) is a specific inhibitor of mitochondrial complex I in the brain which leads to the generation of oxidative stress. To date, [...] Read more.
The high polyphenols content of cranberry accounts for its strong antioxidant activity underlying the beneficial health effects of this fruit. Rotenone (ROT) is a specific inhibitor of mitochondrial complex I in the brain which leads to the generation of oxidative stress. To date, there are few data indicating that toxicity of ROT is not limited to the brain but can also affect other tissues. We aimed to examine whether ROT-induced oxidative stress could be counteracted by cranberry juice not only in the brain but also in the liver and kidney. Wistar rats were given the combined treatment with ROT and cranberry juice (CJ) for 35 days. Parameters of antioxidant status were determined in the organs. ROT enhanced lipid peroxidation solely in the brain. The increase in the DNA damage was noticed in all organs examined and in leukocytes. The beneficial effect of CJ on these parameters appeared only in the brain. Additionally, CJ decreased the activity of serum hepatic enzymes. The effect of CJ on antioxidant enzymes was not consistent, however, in some organs, CJ reversed changes evoked by ROT. Summing up, ROT can cause oxidative damage not only in the brain but also in other organs. CJ demonstrated a protective effect against ROT-induced toxicity. Full article
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Review

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Review
Health-Promoting of Polysaccharides Extracted from Ganoderma lucidum
Nutrients 2021, 13(8), 2725; https://doi.org/10.3390/nu13082725 - 07 Aug 2021
Viewed by 636
Abstract
Medicinal mushrooms are rich sources of pharmacologically active compounds. One of the mushrooms commonly used in traditional Chinese medicine is Ganoderma lucidum (Leyss. Ex Fr.) Karst. In Asian countries it is treated as a nutraceutical, whose regular consumption provides vitality and improves health. [...] Read more.
Medicinal mushrooms are rich sources of pharmacologically active compounds. One of the mushrooms commonly used in traditional Chinese medicine is Ganoderma lucidum (Leyss. Ex Fr.) Karst. In Asian countries it is treated as a nutraceutical, whose regular consumption provides vitality and improves health. Ganoderma lucidum is an important source of biologically active compounds. The pharmacologically active fraction of polysaccharides has antioxidant, immunomodulatory, antineurodegenerative and antidiabetic activities. In this review, we summarize the activity of Ganoderma lucidum polysaccharides (GLP). Full article
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