The Interaction between Metabolome and Microbiome in Nutrition

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrigenetics and Nutrigenomics".

Deadline for manuscript submissions: 25 April 2024 | Viewed by 165

Special Issue Editor

E-Mail Website
Guest Editor
College of Health Sciences, University of Memphis, Memphis, TN 38152, USA
Interests: diet; microbiome; metabolites; metabolism

Special Issue Information

Dear Colleagues,

The human gastrointestinal tract is host to trillions of microbes with a combined genetic potential ten times that of their human host. These gut-resident microbes orchestrate a multitude of activities, resulting in an array of specialized metabolites and bioactive molecules. Diet plays a significant role in shaping this microbial community, while simultaneously serving as a substrate for the generation of microbially produced metabolites. This diet–microbe–metabolite interaction exerts a far-reaching influence on human health and susceptibility to disease. Although the gut microbiome has been implicated in metabolic diseases, defining the specific mechanisms that are altered has proven challenging. Recognizing the pivotal metabolic role played by the gut microbiome in preserving host health or predisposing individuals to disease underscores the need for a deeper understanding of how this complex, dynamic and personalized system interacts with host physiology. This involves an elucidation of diet-responsive microbes, their metabolic outputs, and an understanding of how these bioactive molecules interact with the host’s metabolic processes. The intestinal tract’s microbial inhabitants, the metabolites and their intricate relationship with diet hold the potential to unlock novel therapeutic strategies and mitigate the onset of various diseases.

Dr. Marie van der Merwe
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • diet
  • microbiome
  • metabolites
  • metabolism

Published Papers

This special issue is now open for submission.
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