Nutrition and Infant Colic
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Pediatric Nutrition".
Deadline for manuscript submissions: 15 July 2026 | Viewed by 80
Special Issue Editor
Interests: infantile colic; gastroesophageal reflux disease (GERD); food hypersensitivity; functional gastrointestinal disorders (FGIDs); infant feeding; human milk composition; gut microbiota; early nutritional programming; maternal nutrition; crying behavior
Special Issue Information
Dear Colleagues,
Infantile colic has been defined as disorder of gut–brain interaction (DGBI) in early infancy, characterized by unexplained, recurrent, and prolonged crying and distress without a clear underlying cause. Increasing evidence implicates nutritional factors—including maternal diet, breast milk composition, formula components, feeding practices, and the infant’s developing intestinal microbiome—in its pathogenesis and clinical course. Recent advances in microbiome and metabolomic profiling have provided new insights into how early nutritional exposures modulate gut function, motility, and the gut–brain axis. This Special Issue of Nutrients will improve our current understanding of the many relationships between nutrition, gastrointestinal physiology, and infantile colic by integrating mechanistic, clinical, and translational perspectives. The goal of this Special Issue is to provide a much-needed global forum for high-quality original research, reviews, and interventional studies that explore nutritional determinants of colic onset, prevention, and management. Manuscripts addressing microbiome-mediated mechanisms, bioactive milk constituents, or targeted dietary interventions to improve infant comfort and family well-being are particularly encouraged.
Prof. Dr. Jenifer R. Lightdale
Guest Editor
Manuscript Submission Information
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Keywords
- infantile colic
- disorder of gut–brain interaction (DGBI)
- gut–brain axis
- functional gastrointestinal disorders
- infant nutrition
- gastroesophageal reflux
- food hypersensitivity
- gut microbiome
- early life nutrition
- maternal diet
- breast milk composition
- formula feeding
- infant fussiness
- crying and irritability
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