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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Alkyne Chemistry
edited by Ruimao Hua
submission deadline 25 Nov 2026 | 7 articles | Viewed by 31666 | Submission Open
Keywords: alkyne annulation; carbocycle synthesis; heterocycle synthesis; atom-economic reaction; synthesis methodology
(This special issue belongs to the Section Organic Chemistry)
30th Anniversary of Molecules—Recent Advances in Materials Chemistry
edited by , and Mu-Ping Nieh
submission deadline 30 Nov 2026 | 11 articles | Viewed by 16070 | Submission Open
Keywords: materials chemistry; synthetic procedures; characterization procedures; nanomaterials and nanocomposites; biologically oriented materials and biomaterials; materials of natural origin; hybrid composites; mechanical properties; long-term durability
(This special issue belongs to the Section Materials Chemistry)
Heterophase Polymerization and Functional Polymer Microspheres/Microcapsules
edited by Chengyou Kan and Wei Deng
submission deadline 30 Nov 2026 | 6 articles | Viewed by 10593 | Submission Open
Keywords: emulsion polymerization; mini emulsion polymerization; dispersion polymerization; suspension polymerization; encapsulation; functionalization; polymer microspheres; microcapsules; characterization; morphology control; structure– property relationship; polymer nanocomposite; application
(This special issue belongs to the Section Materials Chemistry)
30th Anniversary of Molecules—Recent Advances in Computational and Theoretical Chemistry
edited by
submission deadline 30 Nov 2026 | 5 articles | Viewed by 6734 | Submission Open
Keywords: computational chemistry; quantum chemistry; density functional theory; molecular design; reaction mechanism; chemical bonding; non-covalent interactions; molecular docking
(This special issue belongs to the Section Computational and Theoretical Chemistry)
Bioactive Components in Plants: Extraction, Characterization and Antioxidant Activity
edited by
submission deadline 15 Dec 2026 | Viewed by 42 | Submission Open
Keywords: bioactive compounds; plant extracts; extraction of bioactives; polyphenols; chemical characterization; antioxidant activity; green chemistry
(This special issue belongs to the Section Natural Products Chemistry)
Characterization of Organic Ligands: Correlations Between Results by Electrochemistry and Other Methods
edited by Eleonora-Mihaela Ungureanu
submission deadline 20 Dec 2026 | 1 articles | Viewed by 676 | Submission Open
Keywords: connections; electrochemical experiments; characterization of organic ligands; DFT calculations of ligand properties; optical methods; electrochemical methods; surface characterization methods (SEM; AFM; Raman; etc.); analytical methods
(This special issue belongs to the Section Applied Chemistry)
30th Anniversary of Molecules: Recent Advances and the Next in Macromolecular Chemistry submission deadline 31 Dec 2026 | 8 articles | Viewed by 13785 | Submission Open
Keywords: macromolecular chemistry; synthetic polymers; natural polymers; polymerization mechanisms and kinetics; supramolecular self-assembly; biological macromolecules
(This special issue belongs to the Section Macromolecular Chemistry)
The 30th Anniversary of Molecules—Recent Advances in Chemical Biology submission deadline 31 Dec 2026 | 6 articles | Viewed by 12415 | Submission Open
Keywords: bioorthogonal chemistry; peptides; nucleic acids; proteins; analytical methods; chemical inhibitors; chemical probe; ubiquitination; structure-activity relationship
(This special issue belongs to the Section Chemical Biology)
30th Anniversary of Molecules—Recent Advances in Inorganic Chemistry submission deadline 31 Dec 2026 | 9 articles | Viewed by 8471 | Submission Open
Keywords: inorganic chemistry; coordination chemistry; solid-state chemistry; nanomaterials; organometallics; transition and main group metal chemistry; catalysis; bioinorganic chemistry
(This special issue belongs to the Section Inorganic Chemistry)
30th Anniversary of Molecules—Recent Advances in Analytical Chemistry submission deadline 31 Dec 2026 | 2 articles | Viewed by 4401 | Submission Open
Keywords: chromatography and advanced mass spectrometry; atomic spectroscopy and elemental mass spectrometry; molecular spectroscopy; miniaturization of analytical instruments; ohmics; nanomaterials and sensors; automation and high-throughput screening; single-cell analysis; non-invasive analysis/techniques; green analytical chemistry
(This special issue belongs to the Section Analytical Chemistry)
30th Anniversary of Molecules—Recent Developments in Biobased Polymers submission deadline 31 Dec 2026 | 2 articles | Viewed by 2430 | Submission Open
Keywords: biobased polymers; sustainability; biodegradability; polymer recycling; polymer composites; polymer processing; green chemistry
(This special issue belongs to the Section Materials Chemistry)
30th Anniversary of Molecules: Recent Advances in Organometallic Chemistry
edited by
submission deadline 31 Dec 2026 | 2 articles | Viewed by 2138 | Submission Open
Keywords: metal– organic framework; organometallic compounds; coordination assembly; metal– organic cluster; metal– organic cage; supramolecular chemistry
(This special issue belongs to the Section Organometallic Chemistry)
Functional Molecules Design for Nutrition Health
edited by and
submission deadline 31 Dec 2026 | Viewed by 63 | Submission Open
Keywords: molecule design; biological activity; nutrition and health; personalized nutrition protocols; precision therapeutic methods
(This special issue belongs to the Section Materials Chemistry)
Advances in Lactam Chemistry: From Synthetic Strategies to Biological Applications
edited by
submission deadline 31 Dec 2026 | Viewed by 46 | Submission Open
Keywords: lactams; sustainable synthesis; structure– activity relationship (SAR); drug discovery; β -lactam analogues; heterocyclic chemistry; therapeutic applications; antimicrobial and anticancer agents
(This special issue belongs to the Section Organic Chemistry)
30th Anniversary of Molecules—Recent Advances in Electrochemistry
edited by
submission deadline 31 Dec 2026 | Viewed by 41 | Submission Open
Keywords: electrochemical science; energy conversion; charge transfer; voltammetry; magnetoelectrochemistry/spin; redox chemistry
(This special issue belongs to the Section Electrochemistry)
Synthesis of Innovative and Smart Materials for Batteries
edited by and Kangyu Zou
submission deadline 31 Dec 2026 | Viewed by 40 | Submission Open
Keywords: batteries; energy storage; electrodes; materials design; smart functional components
(This special issue belongs to the Section Materials Chemistry)
Electrochemical Approaches in Bioanalysis: Translational Applications in Medicine and Environmental Monitoring
edited by Mihaela Tertis
submission deadline 31 Dec 2026 | Viewed by 37 | Submission Open
Keywords: electrochemical bioanalysis; sensors and biosensors; nanomaterials and biomimetic-based platforms; point-of-care diagnostics; environmental monitoring
(This special issue belongs to the Section Electrochemistry)
Advances in Remediation Methods of Pharmaceutical Pollutants in Water submission deadline 31 Dec 2026 | Viewed by 23 | Submission Open
Keywords: drug pollutants; advanced oxidation processes; water treatment; electrochemical methods; photodegradation; degradation pathways; mineralization; toxicity assessment
(This special issue belongs to the Section Green Chemistry)
Recent Advances in Clean and Efficient Coal Separation submission deadline 31 Dec 2026 | Viewed by 5 | Submission Open
Keywords: coal; intelligentization; flotation; gravity separation; dry separation; coal-based materials; coal-based solid waste; interfacial interaction
(This special issue belongs to the Section Green Chemistry)
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