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Special Issue "Forensic Analytical Chemistry"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".

Deadline for manuscript submissions: 30 November 2019

Special Issue Editor

Guest Editor
Prof. Ki-Jung Paeng

Department of Chemistry, Yonsei University, yonseidae-gil 1, Wonju 26493, South Korea
E-Mail
Interests: GC/MS; LC/MS; sample preparation; SPE; chemical sensors; spectroscopies analytical chemistry

Special Issue Information

Dear Colleagues,

Forensic chemistry is defined as the application of chemistry to assist in the elucidation of legal problems. Forensic chemistry embraces a large and diversified field. It includes not only the chemical side of criminal investigation, but also the analysis of any material, the quality of which may give rise to legal proceedings. Forensic chemistry is not limited to purely the chemical questions involved in legal proceedings. It is also related to the other branches of forensic science, such as chemical toxicology, legal medicine, ballistics, questioned documents, dactyloscopy, and photography.  

Forensic chemists should develop the standard methods to give accurate values and/or to detect minute quantities from latent evidence related to crime. The forensic chemist could also develop new chemicals to pursue latent evidences at the crime scene, such as finger print, foot print, blood and other biological fluids, and tissues.

Prof. Ki-Jung Paeng
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • forensic analysis
  • drug analysis
  • molecular and atomic spectrochemical technique
  • electrochemical techniques
  • sensors
  • surface characterization techniques
  • mass spectrometry
  • nuclear magnetic resonance
  • chemometrics and statistics
  • separation sciences

Published Papers (2 papers)

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Research

Open AccessArticle
Multi-Modal Compositional Analysis of Layered Paint Chips of Automobiles by the Combined Application of ATR-FTIR Imaging, Raman Microspectrometry, and SEM/EDX
Molecules 2019, 24(7), 1381; https://doi.org/10.3390/molecules24071381
Received: 18 March 2019 / Revised: 4 April 2019 / Accepted: 8 April 2019 / Published: 8 April 2019
PDF Full-text (3254 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
For the forensic analysis of multi-layered paint chips of hit-and-run cars, detailed compositional analysis, including minor/trace chemical components in the multi-layered paint chips, is crucial for the potential credentials of the run-away car as the number of layers, painting process, and used paints [...] Read more.
For the forensic analysis of multi-layered paint chips of hit-and-run cars, detailed compositional analysis, including minor/trace chemical components in the multi-layered paint chips, is crucial for the potential credentials of the run-away car as the number of layers, painting process, and used paints are quite specific to the types of cars, color of cars, and their surface protection depending on the car manufacturer and the year of manufacture, and yet overall characteristics of some paints used by car manufacturers might be quite similar. In the present study, attenuated total reflectance-Fourier transform infrared (ATR-FTIR) imaging, Raman microspectrometry (RMS), and scanning electron microscopy/energy-dispersive X-ray spectrometric (SEM/EDX) techniques were performed in combination for the detailed characterization of three car paint chip samples, which provided complementary and comprehensive information on the multi-layered paint chips. That is, optical microscopy, SEM, and ATR-FTIR imaging techniques provided information on the number of layers, physical heterogeneity of the layers, and layer thicknesses; EDX on the elemental chemical profiles and compositions; ATR-FTIR imaging on the molecular species of polymer resins, such as alkyd, alkyd-melamine, acrylic, epoxy, and butadiene resins, and some inorganics; and RMS on the molecular species of inorganic pigments (TiO2, ZnO, Fe3O4), mineral fillers (kaolinite, talc, pyrophyllite), and inorganic fillers (BaSO4, Al2(SO4)3, Zn3(PO4)2, CaCO3). This study demonstrates that the new multi-modal approach has powerful potential to elucidate chemical and physical characteristics of multi-layered car paint chips, which could be useful for determining the potential credentials of run-away cars. Full article
(This article belongs to the Special Issue Forensic Analytical Chemistry)
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Open AccessArticle
In Vitro Metabolism of 25B-NBF, 2-(4-Bromo-2,5-Dimethoxyphenyl)-N-(2-Fluorobenzyl)ethanamine, in Human Hepatocytes Using Liquid Chromatography–Mass Spectrometry
Molecules 2019, 24(4), 818; https://doi.org/10.3390/molecules24040818
Received: 29 January 2019 / Revised: 17 February 2019 / Accepted: 22 February 2019 / Published: 25 February 2019
PDF Full-text (2466 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
25B-NBF, 2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-fluorobenzyl)ethanamine, is a new psychoactive substance classified as a phenethylamine. It is a potent agonist of the 5-hydroxytryptamine receptor, but little is known about its metabolism and elimination properties since it was discovered. To aid 25B-NBF abuse screening, the metabolic [...] Read more.
25B-NBF, 2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-fluorobenzyl)ethanamine, is a new psychoactive substance classified as a phenethylamine. It is a potent agonist of the 5-hydroxytryptamine receptor, but little is known about its metabolism and elimination properties since it was discovered. To aid 25B-NBF abuse screening, the metabolic characteristics of 25B-NBF were investigated in human hepatocytes and human cDNA-expressed cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT) enzymes using liquid chromatography–high resolution mass spectrometry. At a hepatic extraction ratio of 0.80, 25B-NBF was extensively metabolized into 33 metabolites via hydroxylation, O-demethylation, bis-O-demethylation, N-debenzylation, glucuronidation, sulfation, and acetylation after incubation with pooled human hepatocytes. The metabolism of 25B-NBF was catalyzed by CYP1A1, CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP2J2, CYP3A4, and UGT2B7 enzymes. Based on these results, it is necessary to develop a bioanalytical method for the determination of not only 25B-NBF but also its metabolites in biological samples for the screening of 25B-NBF abuse. Full article
(This article belongs to the Special Issue Forensic Analytical Chemistry)
Figures

Graphical abstract

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