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Special Issue "Modulation of Quorum Sensing in Bacteria"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Bioorganic Chemistry".

Deadline for manuscript submissions: closed (30 June 2020).

Special Issue Editor

Prof. Dr. Naresh Kumar
Guest Editor
School of Chemistry, University of New South Wales, UNSW Sydney, Australia
Interests: Biologically active molecules; Heterocyclic chemistry; Medicinal chemistry; Design and synthesis of quorum-sensing inhibitors; antimicrobial peptides and mimics; Biomimetic synthesis; Development of new synthetic methodologies; antimicrobial biomaterials
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

With the long-term overuse and misuse of antibiotics, the problem of antibiotic resistance is now reaching a critical stage. Antibiotics are no longer the magic bullets they were once thought to be, and therefore there is an urgent need for the development of alternative therapeutic strategies to combat infections without inducing drug resistance. Quorum sensing (QS) modulation presents a promising alternative strategy, since it attenuates bacterial virulence by disrupting the signaling pathway between bacteria without inducing stress. 

Several strategies to combat this problem are discussed:

i)      The isolation of new natural products with quorum sensing (QS) modulatory activities and the development of their synthetic analogues;
ii)    The synthesis of new classes of QS modulators with anti-virulence and anti-biofilm properties;
iii)  The rational design and structure–activity relationship studies of QS modulators;
iv)  Applications and targeted delivery;
v)    Dual-action and hybrid compounds;
vi)  The synergistic activities of these compounds with other antimicrobials. 

The aim of the Special Issue is to be inclusive and especially to encourage the publication of new and unusual chemical structures with quorum sensing modulation properties. 

Molecules will publish a Special Issue focusing on the “Modulation of Quorum Sensing in Bacteria”, as well as novel molecular targets with reduced capacity to develop antibiotic resistance. It is my pleasure to invite submissions of high-quality research-based papers related to the topics mentioned above.

Prof. Naresh Kumar
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers

There is no accepted submissions to this special issue at this moment.
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