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Special Issue "Focus LMIC: Systems Approaches in Low- and Middle-Income Countries"

A special issue of Molecules (ISSN 1420-3049).

Deadline for manuscript submissions: 31 December 2020.

Special Issue Editors

Dr. Gerard Bryan Gonzales
Guest Editor
Lab of Gastroenterology, Department of Internal Medicine and Pediatrics, Faculty of Medicine and Health Sciences, Ghent University and Inflammation Research Centre, Flemish Institute for Biotechnology (VIB), Belgium
Interests: nutrition; metabolomics; food chemistry; public health; food analysis; nutrimetabolomics
Dr. Natasa Giallourou
Co-Guest Editor
Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK
Interests: metabolomics; systems biology; malnutrition; enteric infections
Dr. Albert Koulman
Co-Guest Editor
NIHR Cambridge BRC Core Metabolomics and Lipidomics Laboratory; NIHR BRC Nutritional Biomarker Laboratory, University of Cambridge, Cambridge, UK
Interests: mass spectrometry; lipidomics; metabolomics; nutritional biomarkers

Special Issue Information

Dear Colleagues,

Advances in systems studies and omics-based technologies allow us to revisit unanswered questions. Nowhere is this more useful than on neglected topics, especially those faced in low- and middle-income countries (LMICs) and low-resource settings. The use of these technologies has provided new perspectives on the molecular underpinnings of, e.g., severe malnutrition in children, pathophysiology of tropical diseases, effect of hygiene and environmental exposures to nutrition and health, and many others. Nonetheless, many topics still remain unexplored. Hence, we would like to invite you to submit a manuscript on this Special Issue on “Focus LMIC: Systems Approaches in Low- and Middle-Income Countries”, where we provide a special forum on studies pertinent to LMICs.

In this Special Issue, we aim to highlight research that utilizes systems approaches to tackle issues concerning LMICs and low-resource settings. Manuscript submissions of particular interest are, though not limited to, the following topics: omics-based approaches for the analysis of disease and nutrition (e.g., malnutrition, HIV), assessment of exposure to poor hygiene and environmental contaminants (exposomics), systems analysis of locally sourced foods, food contaminants in LMICs (e.g., mycotoxins, arsenic), response to vaccines and other drugs among populations in LMICs, capacity building efforts in systems approaches in LMICs, and new methods adapted to the LMIC context. Studies in which the majority of the experimental process has been performed in LMICs (instrumental analysis, clinical studies, bioinformatics) are of special interest. We therefore ask authors to specify which work packages were performed in LMICs and which performed in collaborators in high-resource settings. With this, we aim to highlight the successes in establishing such technologies and encourage efforts to further improve local research capacity in LMICs.

Dr. Albert Koulman
Dr. Gerard Bryan Gonzales
Dr. Natasa Giallourou
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • metabolomics
  • proteomics
  • systems biology
  • low- and middle-income countries
  • tropical diseases
  • vaccines
  • low-resource areas
  • malnutrition
  • nutrition
  • food contaminants
  • environmental exposure
  • capacity building

Published Papers

This special issue is now open for submission.
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