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Special Issue "Recent Advances in Enamides/Ynamides Chemistry"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Bioorganic Chemistry".

Deadline for manuscript submissions: 31 August 2019

Special Issue Editor

Guest Editor
Prof. Isabelle Gillaizeau

Universite d'Orleans, Orleans, France
Website | E-Mail
Interests: methodological studies in heterocyclic chemistry; enamide; ynamide; organometallic chemistry; metal-catalyzed reactions

Special Issue Information

Dear Colleagues,

The continuing demand to create diverse and original libraries of small molecules with useful therapeutic properties and to understand the mechanisms that control biological processes has required the development of efficient and ecofriendly methodologies. This feature is largely determined by two aspects: reaction economy and selectivity, which call for the development of more efficient procedures. The abundance of heterocycles in natural products and biologically active compounds has made them prime targets for the synthetic community. Over the past decade, ynamides and enamides have emerged as relevant functional groups that have been involved in a variety of new synthetic transformations, in particular, in the preparation of natural products, bioactive molecules, and/or complex nitrogen-containing compounds. Regarding the π-donating ability of the nitrogen atom, enamides or ynamides are more electron-rich than simple alkenes or alkynes and are able to show both nucleophilic and electrophilic properties, which are exploited in various synthetic transformations.

Thus, in this current Special Issue, original research papers and reviews on every aspect of synthesis and the application of ynamides and enamides derivatives will be considered. Short communications on the hot topics of this field of ever-growing knowledge are also warmly welcomed.

Prof. Isabelle Gillaizeau
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Enamide synthesis and/or functionalization
  • Ynamide synthesis and/or functionalization
  • Free radical
  • C-H functionalization
  • Catalysis
  • Photochemistry

Published Papers

This special issue is now open for submission.
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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