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Special Issue "Carbonic Anhydrase and Carbonic Anhydrase Inhibitors"

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Bioorganic Chemistry".

Deadline for manuscript submissions: 31 May 2019

Special Issue Editor

Guest Editor
Dr. David J. Augeri

Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Molecular Design and Synthesis, New Brunswick, United States
Website | E-Mail
Interests: drug design; fragment-based drug discovery; small molecules; peptide/protein structure and function; protein-protein interaction inhibitors; anticancer agents; antiinfectives; natural product synthesis and chemistry

Special Issue Information

Dear Colleagues,

This Special Issue entitled “Carbonic Anhydrase and Carbonic Anhydrase Inhibitors” begins with a review on the recent biology and pharmacology of carbonic anhydrase and carbonic anhydrase inhibitors, new findings in autoimmunity, with a medicinal chemistry review of the carbonic anhydrase inhibitors pursued during the last decade, clinically and preclinically, to follow. The collection of research articles is broad, as research in the field has advanced with structural biology yet the prevailing target class supports still the sulfonamides, or close isosteres of sulfonamides. Research articles associated with any of the 14 isoforms of carbonic anhydrase (CA) and their associated CA inhibitors (CAIs); with traditional sulfonamides such as acetazolamide, dichlorophenamide, dorzolamide, and brinzolamide; providing an update on SLC-0111, a new clinically studied phase 1–2 CAlX inhibitor for pancreatic cancer; with a new structural biology study; or with new biophysics will be considered for publication.

Dr. David J. Augeri
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • CA
  • carbonic anhydrase
  • CA I–XII
  • carbonic anhydrase isoform I–XII
  • FTSA
  • fast stop flow analysis
  • fluorescent thermal shift assay
  • ITC
  • isothermal titration calorimetry

Published Papers

This special issue is now open for submission.
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
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