Interactions Between Parasites/Pathogens and Vectors, Second Edition

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Public Health Microbiology".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 887

Special Issue Editors


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Guest Editor
Department of Biosciences, Swansea University, Singleton Park, Swansea SA2 8PP, UK
Interests: gastro-intestinal conditions
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Guest Editor
Zoology/Parasitology Unit, Faculty of Biology and Biotechnology, Ruhr-University Bochum, 44780 Bochum, Germany
Interests: immune system; parasites; vectors
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Special Issue Information

Dear Colleagues,

This Special Issue is the continuation of our previous Special Issue "Interactions Between Parasites/Pathogens and Vectors".

This Special Issue will cover the most important diseases and vectors, including the microbiota of insects. These include the interaction of arboviruses and mosquitoes, viruses and midges, plague bacteria and fleas, malaria parasites and mosquitoes, Leishmania and sandflies, Trypanosoma brucei and tsetse, and Trypanosoma cruzi and triatomines.

The authors are well-known in the scientific community and have published articles on their respective topics. Reviews, original research, and communications focusing on interactions of Borrelia and ticks, interactions of bacteria/viruses and ticks (without Borrelia),  interactions of filarial helminths and mosquitoes, and interactions of Onchocerca and blackflies are welcome.

Prof. Dr. Norman Ratcliffe
Prof. Dr. Günter A. Schaub
Guest Editors

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Keywords

  • arboviruses
  • vectors
  • insects

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Published Papers (1 paper)

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Review

43 pages, 1280 KB  
Review
Interaction of Bacteria and Fleas, Focusing on the Plague Bacterium—A Review
by Patric U. B. Vogel and Günter A. Schaub
Microorganisms 2025, 13(11), 2619; https://doi.org/10.3390/microorganisms13112619 - 18 Nov 2025
Viewed by 808
Abstract
This review summarizes the interactions between three major bacterial groups, Rickettsia sp., Bartonella sp. and Yersinia pestis, the flea vectors and the diverse gut microbiota of fleas and highlights open questions. The focus is on the plague pathogen, Y. pestis, which [...] Read more.
This review summarizes the interactions between three major bacterial groups, Rickettsia sp., Bartonella sp. and Yersinia pestis, the flea vectors and the diverse gut microbiota of fleas and highlights open questions. The focus is on the plague pathogen, Y. pestis, which adapted to transmission by fleas several thousand years ago. This caused one of the deadliest infectious diseases known to mankind, and the three pandemics resulted in an estimated 200 million deaths. In the vector, Y. pestis resists the adverse conditions, like other numerous bacterial species. Rickettsia sp. and Bartonella sp. as well as Y. pestis induce specific changes in the microbiota. The presence of bacteria in the ingested blood activates the production of antimicrobial proteins and reactive oxygen species, which normally have no effect on the development of Y. pestis. This bacterium infects mammals by different modes, first by an early-phase transmission and then by biofilm-mediated blockage of the foregut. Both interfere with blood ingestion and lead to reflux or regurgitation of intestinal contents containing Y. pestis into the bite site. Blockage of the gut leads to more attempts to ingest blood, increasing the risk of transmission. The lifespan of the fleas is also reduced. As Y. pestis is still endemic in wildlife in many regions of the world and human infections continue to occur in limited areas, studies of the interactions are needed to find new ways to control the disease. Full article
(This article belongs to the Special Issue Interactions Between Parasites/Pathogens and Vectors, Second Edition)
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