Detection and Immunity of Avian Viruses

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Veterinary Microbiology".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 468

Special Issue Editors


E-Mail Website
Guest Editor
Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China
Interests: avian influenza
Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China
Interests: avian virology

E-Mail Website
Guest Editor Assistant
Department of Avian Infectious Diseases, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China
Interests: poultry immunization; virus

Special Issue Information

Dear Colleagues,

Avian viruses, including highly pathogenic avian influenza and zoonotic pathogens, pose significant threats to poultry industries and human health. With poultry being a major protein source in the world, the scale of farming creates an ideal environment for viral evolution and transmission. Early detection and understanding of avian viral immunity are crucial for effective disease control and prevention. Advances in diagnostic technologies have improved pathogen identification, but challenges remain in understanding host immune responses and developing effective vaccines.

This Special Issue focuses on the detection and immunity of avian viruses. We invite submissions on novel diagnostic techniques, immune responses in poultry and wild birds, vaccine development, and host genetic factors influencing susceptibility. By highlighting recent advancements, we aim to enhance our understanding of avian viral diseases and contribute to their control and prevention.

Dr. Qiaoyang Teng
Dr. Dawei Yan
Guest Editors

Dr. Xue Pan
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • avian viruses
  • detection techniques
  • immune response
  • poultry health
  • zoonotic pathogens
  • vaccine development
  • host genetics
  • diagnostic advances
  • viral evolution
  • disease control

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

13 pages, 2134 KB  
Article
Development of a Blocking ELISA for Detection of Serum Neutralizing Antibodies Against Duck Adenovirus Type 3
by Mei Tang, Xiaona Shi, Yifei Xiong, Chunxiu Yuan, Qinmin Zhu, Minfan Huang, Bangfeng Xu, Qinfang Liu, Xue Pan, Zhifei Zhang, Qiaoyang Teng, Minghao Yan, Dawei Yan and Zejun Li
Microorganisms 2025, 13(11), 2607; https://doi.org/10.3390/microorganisms13112607 - 16 Nov 2025
Viewed by 356
Abstract
In 2014, Duck Adenovirus type 3 (DAdV-3) emerged in Muscovy ducks and has since spread rapidly across China, causing significant economic losses to the duck industry. Given this situation, the development of reliable diagnostic tools is crucial for effective disease control. In this [...] Read more.
In 2014, Duck Adenovirus type 3 (DAdV-3) emerged in Muscovy ducks and has since spread rapidly across China, causing significant economic losses to the duck industry. Given this situation, the development of reliable diagnostic tools is crucial for effective disease control. In this study, a neutralizing monoclonal antibody (mAb) 2F12 specific to DAdV-3 was generated, which showed a blocking rate of over 70% and a neutralization titer of up to 1:794. A blocking enzyme-linked immunosorbent assay (b-ELISA) was further developed based on mAb 2F12 to efficiently detect neutralizing antibodies against DAdV-3. The cut-off values of percent inhibition (PI) were set based on testing 84 negative duck serum samples, with a value below 16.79% (mean (X¯) + 2 standard deviations (SD)) for negative sera and over 21.62% (X¯ + 3SD) for positive sera. The b-ELISA exhibited a high specificity, reacting exclusively with DAdV-3 positive serum and showing no cross-reactivity with other representative positive sera tested. Additionally, the b-ELISA showed significantly higher sensitivity than the serum neutralization test (SNT), detecting antibodies 16-fold greater than the endpoint dilution of the SNT. The established b-ELISA, validated with 90 field serum samples from six duck farms, was well-suited for clinical detection of DAdV-3 antibodies and for monitoring post-vaccination antibody levels, representing a significant advancement in DAdV-3 detection and prevention. Full article
(This article belongs to the Special Issue Detection and Immunity of Avian Viruses)
Show Figures

Figure 1

Back to TopTop