Special Issue "Metabolic Regulation of Prebiotics and Probiotics and Gut Microbiota"

Dear Colleagues,

In recent years, the incidence of metabolic syndrome, which is characterized by metabolic disorders such as type II diabetes, hyperlipidemia, and hypertension, has been increasing, which has seriously affected public health. The imbalance of gut microbiota is one of the factors leading to metabolic syndrome. Probiotics, represented by Lactobacillus and Bifidobacterium, can regulate the intestinal microecological balance, regulate the body's metabolism and reshape the intestinal environment, to alleviate the occurrence and development of metabolic syndrome. At present, most studies focus on the effect of probiotics in the prevention and treatment of metabolic diseases, but the mechanism of action of probiotics is not discussed enough. The reasons are mainly attributed to the complex etiology of various metabolic diseases, the differences in the probiotic effects of different strains of probiotics, and the different mechanisms of probiotics in alleviating metabolic syndrome. Prebiotics/biogens are metabolites or microbial components of probiotics that can still play a role after inactivation treatment. They have the health functions of regulating the body's immunity, protecting the intestinal barrier, and regulating gut microbiota.

At present, due to the limitations of research techniques, most studies only focus on proteins, polysaccharides, and other bioactive substances, and fail to accurately classify and identify more effector substances. Therefore, we aim to explore more research on probiotics, prebiotics, gut microbiota, and metabolic related issues. Our research is not limited to different sources and different processing methods, with more focus on the exploration of the mechanism of action.

Dr. Lianliang Liu
Dr. Lei Wang
Guest Editors

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• metabolic syndrome
• hyperlipidemia
• hypertension
• Lactobacillus
• metabolic syndrome
• probiotics
• prebiotics
• gut microbiota
• bioactive substances