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Medicina publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Ophthalmology: New Diagnostic and Treatment Approaches (2nd Edition)

edited by

Stephen G. Schwartz

Andrzej Grzybowski

, Victor M. Villegas, Christopher Leffler and Krishna S. Kishor

submission deadline 25 Apr 2026 | 1 articles | Viewed by 514 | Submission Open

Keywords: ophthalmology; ocular imaging; anti-vascular endothelial growth factor agents; complement inhibitors; intraocular surgery; genetic testing; intraocular lenses

(This special issue belongs to the Section Ophthalmology)

Advances in Structural Heart Diseases

edited by

Konstantinos Papadopoulos

Ignatios Ikonomidis

and Erwan Donal

submission deadline 25 Apr 2026 | Viewed by 261 | Submission Open

Keywords: valvular heart diseases; transcatheter interventions; TEER; LAA closure; ASD closure; interventional echocardiography; multimodality cardiac imaging; three-dimensional echocardiography

(This special issue belongs to the Section Cardiology)

Translational Advances in Gynecologic Cancers

edited by Prapaporn Suprasert and Chalong Cheewakriangkrai

submission deadline 25 Apr 2026 | Viewed by 71 | Submission Open

Keywords: gynecologic cancer; translational research; molecular biomarkers; precision medicine; targeted therapy; immunotherapy; clinical trials; artificial intelligence in oncology

(This special issue belongs to the Section Obstetrics and Gynecology)

Coronary Physiology and Microvascular Dysfunction in Ischemia with Non-Obstructive Coronary Arteries: Advances and Challenges

edited by

Kyriakos Dimitriadis

and

Athanasios Sakalidis

submission deadline 28 Apr 2026 | Viewed by 79 | Submission Open

Keywords: coronary physiology; coronary microvascular dysfunction; coronary flow reserve; ischemia with no obstructive arteries; coronary microcirculation; myocardial infarction with non-obstructive coronary arteries; microvascular angina; thermodilution; stable angina

(This special issue belongs to the Section Cardiology)

New Development of Rehabilitation Interventions for People with Complex Psychosis

edited by

Emanuele Caroppo

Marianna Mazza

and Giuseppe Marano

submission deadline 28 Apr 2026 | Viewed by 79 | Submission Open

Keywords: complex psychosis; psychiatric rehabilitation; cognitive remediation; recovery-oriented care; digital health interventions

(This special issue belongs to the Section Psychiatry)

Cardiovascular Diseases and Type 2 Diabetes: 2nd Edition

edited by

Cristina Tudoran

submission deadline 30 Apr 2026 | 6 articles | Viewed by 10462 | Submission Open

Keywords: acute and chronic coronary syndrome; endothelial dysfunction; arterial hypertension; heart failure; insulin resistance; diabetes mellitus type 2

(This special issue belongs to the Section Endocrinology)

Autoimmune Diseases: Advances and Challenges

edited by

Abdulla Watad

Kassem Sharif

and Niv Ben-Shabat

submission deadline 30 Apr 2026 | 4 articles | Viewed by 6166 | Submission Open

Keywords: autoimmunity; inflammation; arthritis; psoriasis; metabolic syndrome; lupus; thyroiditis; vasculitis; autoinflammatory conditions

(This special issue belongs to the Section Hematology and Immunology)

Gastric Sleeve Surgery: Techniques, Outcomes, and Future Directions

edited by Anna Maria Różańska-Walędziak and

Maciej Walędziak

submission deadline 30 Apr 2026 | 3 articles | Viewed by 5988 | Submission Open

Keywords: laparoscopic sleeve gastrectomy; bariatric surgery; obesity

(This special issue belongs to the Section Surgery)

Kidney Transplantation Complications: Updates and Challenges

edited by

Kumar Digvijay

and Henrik Birn

submission deadline 30 Apr 2026 | 2 articles | Viewed by 5207 | Submission Open

Keywords: kidney transplantation; complications; infection; rejection; immunosuppression; diagnosis; prevention; treatment; long-term outcomes; patient care

(This special issue belongs to the Section Urology & Nephrology)

Coronary Artery Disease from Acute Manifestation to Long Term Consequences

edited by

Elena Emilia Babeş

submission deadline 30 Apr 2026 | 2 articles | Viewed by 3785 | Submission Open

Keywords: coronary artery disease; acute coronary syndrome; coronary revascularization; coronary angiography; CT angiography; antiplatelet therapy; inflammation

(This special issue belongs to the Section Cardiology)

Advances in Colorectal Surgery and Oncology

edited by Jasneet Singh Bhullar

submission deadline 30 Apr 2026 | 3 articles | Viewed by 2393 | Submission Open

Keywords: colorectal surgery; robotic-assisted surgery; artificial intelligence (AI) in colonoscopy; organ preservation strategies; anorectal disease management

(This special issue belongs to the Section Surgery)

Underserved Ophthalmology Healthcare

edited by

Jay Chhablani

and Anindya Samanta

submission deadline 30 Apr 2026 | 2 articles | Viewed by 1404 | Submission Open

Keywords: underserved ophthalmology; unsheltered ophthalmology; homeless ophthalmology; telemedicine; mobile ophthalmology clinic; free ophthalmology clinic

(This special issue belongs to the Section Ophthalmology)

Outcomes After Surgical Treatment of Pelvic Organ Prolapse

edited by Justina Kačerauskienė and Roger Roman Dmochowski

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1307 | Submission Open

Keywords: pelvic organ prolapse; surgery; recurrence; vaginal hysterectomy; sacrocolpopexy; Manchester operation; sacrospinous fixation; native tissue

(This special issue belongs to the Section Obstetrics and Gynecology)

Physiotherapy for Head and Neck Cancer

edited by

Ernesto Anarte-Lazo

submission deadline 30 Apr 2026 | 1 articles | Viewed by 1266 | Submission Open

Keywords: physiotherapy; head and neck cancer; neuromusculoskeletal impairments

(This special issue belongs to the Section Oncology)

Updates on Allergies and Immunodeficiencies

edited by

Carmen Panaitescu

and

Maria Roxana Buzan

submission deadline 30 Apr 2026 | 1 articles | Viewed by 486 | Submission Open

Keywords: allergy; immunodeficiency; allergens; cross-reactivity; molecular allergy diagnostics; immunotherapy; precision medicine; exposome

(This special issue belongs to the Section Hematology and Immunology)

Recent Advances in Otological Diseases

edited by

Andrea Frosolini

submission deadline 30 Apr 2026 | Viewed by 319 | Submission Open

Keywords: otology; hearing loss; tinnitus; otitis media; vestibular disorders; diagnostic methods; treatment; surgery; epidemiology; medical devices

Innovations in Sports Injury Prevention and Rehabilitation

edited by

Sofia Xergia

and

Nikolaos I. Liveris

submission deadline 30 Apr 2026 | Viewed by 190 | Submission Open

Keywords: sports injury rehabilitation; injury prevention; risk factors; return-to-play (RTP) criteria; biomechanical analysis; sports psychology; surgical intervention methods; ligament repair; joint reconstruction; physical therapy and rehabilitation

(This special issue belongs to the Section Orthopedics)

Recent Breakthroughs in Orthodontic Treatment

edited by

Saverio Cosola

and

Michela Boccuzzi

submission deadline 30 Apr 2026 | Viewed by 181 | Submission Open

Keywords: orthodontics; digital orthodontics; artificial intelligence; clear aligners; biomaterial; skeletal anchorage; CAD– CAM technology; customized appliances; oral health

(This special issue belongs to the Section Dentistry and Oral Health)

Trauma-Associated Tinnitus and Hearing Loss

edited by

Sebastian Cozma

and Madalina Gabriela Georgescu

submission deadline 30 Apr 2026 | Viewed by 151 | Submission Open

Keywords: acute tinnitus; chronic tinnitus; tinnitus related quality of life; traumatic brain injury; cochlear concussion; third window syndrome; tinnitus management

(This special issue belongs to the Section Neurology)

Application of Endoscopy in Gastrointestinal Disease

edited by

Irina Girleanu

Cristina Muzica

and Ana Maria Trofin

submission deadline 30 Apr 2026 | Viewed by 115 | Submission Open

Keywords: gastrointestinal endoscopy; colonoscopy; colorectal cancer screening; endoscopic therapy; EMR and ESD; artificial intelligence in endoscopy; upper GI endoscopy; GI bleeding; image-enhanced endoscopy; therapeutic endoscopy

(This special issue belongs to the Section Gastroenterology & Hepatology)

Clinical Diagnosis and Management of Cardiovascular Disease

edited by Federica Marzano,

Paola Gargiulo

and Stefania Paolillo

submission deadline 30 Apr 2026 | Viewed by 99 | Submission Open

Keywords: cardiovascular disease; clinical diagnosis; risk stratification; biomarkers; cardiovascular imaging; personalized medicine; therapeutic management; preventive cardiology

(This special issue belongs to the Section Cardiology)

Advances in Laparoscopic Surgery

edited by

Mario Palumbo

and

Luigi Della Corte

submission deadline 30 Apr 2026 | Viewed by 99 | Submission Open

Keywords: laparoscopic surgery; minimally invasive gynecology; robotic-assisted surgery intraoperative ultrasound; hysteroscopy; gynecologic oncology; endometriosis; benign gynecology

(This special issue belongs to the Section Surgery)

New Insights into Heart Failure Management and Treatment

edited by

Alejandro N. Barbagelata

and Edgardo J. Kaplinsky

submission deadline 30 Apr 2026 | Viewed by 95 | Submission Open

Keywords: heart failure; cardiovascular disease; treatment advances; management strategies; personalized medicine; clinical guidelines; diagnostic innovations; multidisciplinary care; emerging therapies; patient outcomes

(This special issue belongs to the Section Cardiology)

Tendon Injury and Reconstruction

edited by

Marisa Megna

, Maurizio Ranieri and

Riccardo Marvulli

submission deadline 30 Apr 2026 | Viewed by 82 | Submission Open

Keywords: tendon injuries; tendon function; pain management; physical therapy; tendon rehabilitation; shock waves therapy; health promotion; pain perception; biological terapies; tendon surgery

(This special issue belongs to the Section Orthopedics)

Recent Progress in Cardiac Surgery

edited by

Giuseppe Nasso

and

Walter Vignaroli

submission deadline 30 Apr 2026 | Viewed by 80 | Submission Open

Keywords: mitral valve; TAVI; aortic valve; coronary artery bypass; ascending aorta; valve sparing; innovation in cardiac surgery; ventricular assist device; ECMO; cardiac support

(This special issue belongs to the Section Cardiology)

Advances in Total Hip Arthroplasty: From Diagnosis to Treatment

edited by

Thomas W. Wainwright

and

Rob Middleton

submission deadline 30 Apr 2026 | Viewed by 76 | Submission Open

Keywords: total hip arthroplasty; preoperative planning and imaging; robotics and navigation; patient-specific instrumentation; smart prostheses; augmented reality in surgery; digital rehabilitation; multidisciplinary care

(This special issue belongs to the Section Orthopedics)

Advances in the Prevention and Treatment of Mycobacterial Diseases

edited by

Selvakumar Subbian

submission deadline 30 Apr 2026 | Viewed by 70 | Submission Open

Keywords: mycobacterium tuberculosis; non-tuberculous mycobacteria; tuberculosis; granuloma; pathogenesis; antimicrobial drug resistance; molecular diagnostics; host-directed therapy; BCG vaccine; immune response; host– pathogen interactions

(This special issue belongs to the Section Infectious Disease)

Recent Advances in Autoimmune Rheumatic Diseases—3rd Edition

edited by

Diana Mieliauskaitė

submission deadline 30 Apr 2026 | Viewed by 68 | Submission Open

Keywords: autoimmune rheumatic diseases; rheumatoid arthritis; systemic lupus erythematosus; Sjogren’ s disease; systemic scleroderma; psoriatic arthritis; mixed connective tissue disease; ankylosing spondylitis; vasculitides; juvenile arthritis; rare autoimmune rheumatic diseases

(This special issue belongs to the Section Hematology and Immunology)

Psychosis Mechanisms and Interventions

edited by

Giorgia Varallo

and

Valentina Baldini

submission deadline 30 Apr 2026 | Viewed by 66 | Submission Open

Keywords: psychosis; neurobiology; early intervention; cognitive dysfunction; trauma; dopamine; sleep disturbances; antipsychotics; digital psychiatry; precision medicine

(This special issue belongs to the Section Psychiatry)

The Role of Arthroscopy in Modern Orthopedics

edited by

Jae-Sung Yoo

submission deadline 30 Apr 2026 | Viewed by 65 | Submission Open

Keywords: arthroscopy; minimally invasive surgery; soft tissue preservation; high-resolution imaging; surgical precision; small joint arthroscopy; special condition arthroscopy

(This special issue belongs to the Section Orthopedics)

Perioperative Medicine: Optimizing Outcomes Through Anesthesia

edited by

Lucía Valencia

submission deadline 30 Apr 2026 | Viewed by 62 | Submission Open

Keywords: anesthesia; analgesia; enhanced recovery after surgery; intensive care unit

(This special issue belongs to the Section Intensive Care/ Anesthesiology)

Immune Checkpoint Inhibitors for Thoracic Malignant Tumors

edited by

Hisao Imai

submission deadline 30 Apr 2026 | Viewed by 60 | Submission Open

Keywords: immune checkpoint inhibitors; thoracic malignancies; non-small cell lung cancer; small cell lung cancer; malignant pleural mesothelioma; PD-1/PD-L1 blockade; combination immunotherapy; biomarkers; tumor microenvironment; resistance mechanisms

(This special issue belongs to the Section Oncology)

An Update to the Epidemiology, Diagnostic Challenges, and Molecular Bases of Nonalcoholic Fatty Liver Disease: 2nd Edition

edited by

Galileo Escobedo

submission deadline 30 Apr 2026 | Viewed by 57 | Submission Open

Keywords: fatty liver disease; steatohepatitis; fibrosis; COVID-19 lockdown; insulin resistance; metabolic syndrome; T cell; macrophage; computed tomography; magnetic resonance imaging

(This special issue belongs to the Section Gastroenterology & Hepatology)

Optimizing Athlete Health and Performance: Multidisciplinary Perspectives in Sports Medicine

edited by

Carlos Braga

and

Júlio A. Costa

submission deadline 1 May 2026 | 1 articles | Viewed by 406 | Submission Open

Keywords: sports medicine; athlete health; performance optimization; injury prevention; multidisciplinary approaches; rehabilitation; nutrition in sports; wearable technologies; preventive medicine; sports psychology

Advances in Reproductive Health

edited by

Anca Huniadi

submission deadline 1 May 2026 | Viewed by 376 | Submission Open

Keywords: in vitro fertilization; PGT-A; non-invasive embryo testing; chronic endometritis; embryo culture; aneuploidy; artificial intelligence

(This special issue belongs to the Section Obstetrics and Gynecology)

Hematologic Malignancies: Diagnosis, Prognosis and Management

edited by Ádám Jona and

Zsófia Miltényi

submission deadline 1 May 2026 | Viewed by 141 | Submission Open

Keywords: malignant lymphoma; treatment; prognostication; stem cell transplantation; cellular therapy

(This special issue belongs to the Section Oncology)

Bariatric Surgery and Postoperative Management

edited by

Adam Abu Abeid

submission deadline 1 May 2026 | Viewed by 63 | Submission Open

Keywords: bariatric surgery; metabolic surgery; obesity treatment; postoperative management; revisional surgery; nutritional outcomes; complications; weight regain; comorbidity resolution; long-term follow-up

(This special issue belongs to the Section Surgery)

Diagnosis, Management, and Treatment of Hearing Loss

edited by

Francesco Ciodaro

and

Daniele Portelli

submission deadline 10 May 2026 | Viewed by 100 | Submission Open

Keywords: hearing loss; otology; auditory rehabilitation; hearing aids; cochlear implants; regenerative medicine; precision audiology; artificial intelligence; tele-audiology; hearing health

Diabetic Retinopathy: Advances in Diagnosis and Therapeutic Strategies

edited by

Rossella D'Aloisio

and Marco Rocco Pastore

submission deadline 10 May 2026 | Viewed by 91 | Submission Open

Keywords: diabetes mellitus; diabetic retinopathy; diabetic macular edema; retinal imaging; anti-vascular endothelial growth factor injections; dexamethasone implant; vitreoretinal surgery; photocoagulation laser; diabetic eye-screening program; artificial intelligence

(This special issue belongs to the Section Ophthalmology)

Perioperative Care and Surgical Techniques in Colorectal Cancer

edited by

Giulia Turri

and

Raffaele De Luca

submission deadline 10 May 2026 | Viewed by 43 | Submission Open

Keywords: colorectal cancer; laparoscopy; robotic surgery; minimally invasive surgery; perioperative care; enhanced recovery after surgery; prehabilitation

(This special issue belongs to the Section Surgery)

Ophthalmology, Environment, and Lifestyle: New Pathways in Diagnosis and Treatment

edited by Jesús Merayo-Lloves and Rodrigo Martin Torres

submission deadline 15 May 2026 | 2 articles | Viewed by 1732 | Submission Open

Keywords: vision science; ophthalmology; environment; lifestyle; aging

(This special issue belongs to the Section Ophthalmology)

Translating CBT for OCD into Practice: Modalities, Effectiveness, and Implementation

edited by

Keiichiro Mukai

and Bethany May Wootton

submission deadline 15 May 2026 | Viewed by 171 | Submission Open

Keywords: obsessive– compulsive disorder (OCD); cognitive behavioral therapy (CBT); treatment effectiveness; stepped care; low-intensity CBT with ICT (e.g.; apps; online programs); high-intensity CBT (e.g.; inpatient; residential); access to care; therapist variation; cost-effectiveness; healthcare implementation

(This special issue belongs to the Section Psychiatry)

Clinical Diagnosis and Treatment of Osteoporosis and Fractures

edited by Nicolas Martinez-Velilla,

Bernardo Abel Cedeño-Veloz

and

Jose Manuel Cancio-Trujillo

submission deadline 15 May 2026 | Viewed by 161 | Submission Open

Keywords: osteoporosis; fragility fractures; bone mineral density (DXA); FRAX score; bone turnover markers; precision medicine; artificial intelligence; proteomic biomarkers; anabolic and antiresorptive therapies; integrated care for fracture patients

(This special issue belongs to the Section Orthopedics)

Advances in Use of PET-CT Imaging in Disease Diagnosis

edited by Ana María García-Vicente and

Edel Noriega-Álvarez

submission deadline 15 May 2026 | Viewed by 121 | Submission Open

Keywords: PET-CT; molecular imaging; diagnostic imaging; radiotracers; oncology; inflammation and infection; neurology; cardiovascular imaging; artificial intelligence in imaging; precision medicine

Advances in the Diagnosis and Management of Scoliosis: A Multidisciplinary Approach

edited by

Mark W. Morningstar

submission deadline 15 May 2026 | Viewed by 57 | Submission Open

Keywords: scoliosis; diagnosis; management; multidisciplinary approach; non-radiographic assessment; surface topography; three-dimensional ultrasound; rehabilitation; patient-centred care; innovative technologies

(This special issue belongs to the Section Orthopedics)

Updates on Chronic Heart Failure and Hypertension

edited by

Ioannis Leontsinis

and

Eleni Manta

submission deadline 15 May 2026 | Viewed by 42 | Submission Open

Keywords: hypertension; heart failure; pathophysiology; device therapy; treatment; research; biomarkers

(This special issue belongs to the Section Cardiology)

Advances in Thoracic Surgery and Lung Cancer Treatment

edited by

Seyer Safi

and Katrin Welcker

submission deadline 15 May 2026 | Viewed by 41 | Submission Open

Keywords: lung cancer; hybrid operation; one-stop shop; segmentectomy

(This special issue belongs to the Section Pulmonology)

Combined Anterior Cruciate Ligament Reconstruction and Lateral Augmentation

edited by Theofylaktos Kyriakidis and Dimitrios Koulalis

submission deadline 15 May 2026 | Viewed by 37 | Submission Open

Keywords: anterior cruciate ligament reconstruction (ACLR); anterolateral ligament reconstruction; lateral extra-articular tenodesis; anterolateral rotatory instability; knee instability; clinical outcomes

(This special issue belongs to the Section Orthopedics)

New Insights into Neurodevelopmental Biology and Disorders

edited by

Rekha Jagadapillai

submission deadline 20 May 2026 | 3 articles | Viewed by 9706 | Submission Open

Keywords: neurodevelopment; neurodevelopmental biology; neurodevelopmental disorders; autism spectrum disorders (ASDs); down syndrome; ADHD; cerebral palsy; learning disability

(This special issue belongs to the Section Neurology)

Intracranial Aneurysms, Subarachnoid Hemorrhage and Delayed Cerebral Ischemia

edited by Leszek Michał Sagan and

Tomasz Klepinowski

submission deadline 20 May 2026 | 3 articles | Viewed by 6538 | Submission Open

Keywords: intracranial aneurysm; subarachnoid hemorrhage; vasospasm; delayed cerebral ischemia; stroke; embolization; coiling; clipping

(This special issue belongs to the Section Neurology)

Displaying special issue 201-250 on page 5 of 8.

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