Special Issue "Essential Fatty Acids or Bioactive Lipids in Health and Disease"

A special issue of Medicina (ISSN 1010-660X).

Deadline for manuscript submissions: closed (15 November 2020).

Special Issue Editor

Prof. Dr. Das Undurti
Website1 Website2
Guest Editor
UND Life Sciences, 2221 NW 5th St, Battle Ground, WA 98604, USA
Interests: essential fatty acids; eicosanoids; cytokines; free radicals; nitric oxide; melatonin and their role in various clinical conditions

Special Issue Information

Dear Colleagues,

Traditionally, the roles of proteins, antibodies, cytokines, growth factors, and their receptors have been emphasized in health and disease. Very little interest or emphasis has been placed on lipids. In general, the word “lipids” means cholesterol, triglycerides, HDL, and LDL for many. However, another group of lipids derived from the dietary essential fatty acids (linoleic acid and a-linolenic acid), such as g-linolenic acid, dihomo-g-linolenic acid, arachidonic acid, eicosapentaenoic acid, docosapentaenoic acid, and docosahexaenoic acid and their pro- and anti-inflammatory metabolites, such as prostaglandins and lipoxins, resolvins, protectins, and maresins (all can be called bioactive lipids),  respectively, have received much less attention. In recent years, the role of these bioactive lipids in health and disease started receiving considerable notice. These bioactive lipids seem to play a fundamental role in inflammation and immune response regulation, which may explain their involvement in diseases such as obesity, diabetes mellitus, hypertension, insulin resistance, cancer, and autoimmune diseases, and several neurological conditions including Alzheimer’s disease. Hence, we think that a Special Issue devoted to bioactive lipids, essential fatty acids, and their metabolites is due. We call upon all those who are interested in this important subject to contribute to this Special Issue with emphasis on their clinical implications. 

Prof. Dr. Undurti N Das, MD, DSc, FAMS, FRSC
Guest Editor

Manuscript Submission Information

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Keywords

  • essential fatty acids
  • bioactive lipids
  • linoleic acid
  • arachidonic acid
  • eicosapentaenoic acid
  • docosahexaenoic acid
  • prostaglandins
  • lipoxins
  • resolvins
  • protectins
  • maresins
  • health
  • diseases
  • inflammation
  • cytokines
  • immune response
  • free radicals

Published Papers (1 paper)

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Open AccessCommentary
Can Bioactive Lipid Arachidonic Acid Prevent and Ameliorate COVID-19?
Medicina 2020, 56(9), 418; https://doi.org/10.3390/medicina56090418 - 19 Aug 2020
Cited by 1
Abstract
It is proposed that the bioactive lipid, arachidonic acid (AA, 20:4 n-6), can inactivate severe acute respiratory syndrome(SARS-CoV-2), facilitate M1 and M2 macrophage generation, suppress inflammation, prevent vascular endothelial cell damage, and regulate inflammation resolution processes based on the timely formation of prostaglandin [...] Read more.
It is proposed that the bioactive lipid, arachidonic acid (AA, 20:4 n-6), can inactivate severe acute respiratory syndrome(SARS-CoV-2), facilitate M1 and M2 macrophage generation, suppress inflammation, prevent vascular endothelial cell damage, and regulate inflammation resolution processes based on the timely formation of prostaglandin E2 (PGE2) and lipoxin A4 (LXA4) based on the context. Thus, AA may be useful both to prevent and manage coronavrus disease-2019(COVID-19). Full article
(This article belongs to the Special Issue Essential Fatty Acids or Bioactive Lipids in Health and Disease)
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