Special Issue "Quantitative Trait Loci"

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Genetics and Genomics".

Deadline for manuscript submissions: 15 May 2021.

Special Issue Editor

Dr. Akira Ishikawa
E-Mail Website
Guest Editor
Laboratory of Animal Genetics and Breeding, Department of Animal Sciences, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan
Interests: quantitative trait loci; quantitative traits; genetics; laboratory animal; poultry; livestock

Special Issue Information

Dear Colleagues,

Quantitative traits are of great importance in agriculture, medicine, and evolution. Recent advances in high-throughput technologies, including next-generation sequencing and omics, have provided opportunities to identify great numbers of quantitative trait loci (QTLs) for molecular traits (e.g., gene expression, protein expression, and DNA methylation) as well as traditional quantitative traits (e.g., body weight, height, obesity, and diabetes). However, most QTLs are located in noncoding genomic regions, making it difficult to discover causal genes, referred to as quantitative trait genes (QTGs), and, further, to identify causal genetic variants, referred to as quantitative trait nucleotides (QTNs). Hence, it is still challenging to understand the link between genotype and phenotype at the genetic and molecular levels. QTL studies that are integrated with multi-omics approaches and causality analysis in the same individuals can accelerate the identification of candidate QTGs and/or QTNs, and they may provide evidence for the biological interpretation of the candidates.

In this Special issue of Life, we welcome original articles and reviews covering all aspects related to the genetic architecture of quantitative and molecular traits in animals, including humans, laboratory animals, livestock, and poultry. These include discoveries of QTLs, QTGs, or QTNs with important traits for agriculture, medicine, and evolution. Especially, we are seeking manuscripts leading to advancement in our understanding of the link between genotype and phenotype.

Dr. Akira Ishikawa
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • quantitative traits
  • molecular traits
  • QTL
  • QTG
  • QTN
  • animals
  • humans
  • laboratory animals
  • livestock
  • poultry

Published Papers

This special issue is now open for submission.
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