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Frontiers Research in Stroke: Cortical Biomarkers Based on the Combined...
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Frontiers Research in Stroke: Cortical Biomarkers Based on the Combined Use of TMS and EEG

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Mechanisms of Diseases".

Deadline for manuscript submissions: closed (15 April 2022) | Viewed by 3599

Special Issue Editor

Dr. Elias Paolo Casula

E-Mail Website
Guest Editor
Non-Invasive Brain Stimulation Unit, IRCCS Santa Lucia Foundation, 00142 Rome, Italy
Interests: transcranial magnetic stimulation; electroencephalography; brain plasticity; stroke; neurodegenerative disease

Special Issue Information

Dear Colleagues,

In recent years, the use of transcranial magnetic stimulation (TMS) in combination with electroencephalography (EEG) has facilitated the investigation of cortical dynamics in the healthy and pathological brain. In stroke, the stimulation of specific areas of the affected or non-affected hemisphere, while recording EEG activity, can reveal cortical biomarkers in terms of abnormal connectivity or interhemispheric imbalance. These indexes can be useful to distinguish different grades of stroke severity and potentially could have a prognostic value for clinical recovery. This Special Issue of the Journal of Personalized Medicine aims to highlight the current state of the art in this field and show the latest findings in the field of stroke and TMS–EEG.

Dr. Elias Paolo Casula
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • transcranial magnetic stimulation
  • electroencephalography
  • stroke
  • biomarkers
  • brain dynamics

Published Papers (1 paper)

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Review

17 pages, 1130 KiB  
Review
A New Framework to Interpret Individual Inter-Hemispheric Compensatory Communication after Stroke
by Arianna Brancaccio, Davide Tabarelli and Paolo Belardinelli
J. Pers. Med. 2022, 12(1), 59; https://doi.org/10.3390/jpm12010059 - 06 Jan 2022
Cited by 7 | Viewed by 3237
Abstract
Stroke constitutes the main cause of adult disability worldwide. Even after application of standard rehabilitation protocols, the majority of patients still show relevant motor impairment. Outcomes of standard rehabilitation protocols have led to mixed results, suggesting that relevant factors for brain re-organization after [...] Read more.
Stroke constitutes the main cause of adult disability worldwide. Even after application of standard rehabilitation protocols, the majority of patients still show relevant motor impairment. Outcomes of standard rehabilitation protocols have led to mixed results, suggesting that relevant factors for brain re-organization after stroke have not been considered in explanatory models. Therefore, finding a comprehensive model to optimally define patient-dependent rehabilitation protocols represents a crucial topic in clinical neuroscience. In this context, we first report on the rehabilitation models conceived thus far in the attempt of predicting stroke rehabilitation outcomes. Then, we propose a new framework to interpret results in stroke literature in the light of the latest evidence regarding: (1) the role of the callosum in inter-hemispheric communication, (2) the role of prefrontal cortices in exerting a control function, and (3) diaschisis mechanisms. These new pieces of evidence on the role of callosum can help to understand which compensatory mechanism may take place following a stroke. Moreover, depending on the individual impairment, the prefrontal control network will play different roles according to the need of high-level motor control. We believe that our new model, which includes crucial overlooked factors, will enable clinicians to better define individualized motor rehabilitation protocols. Full article
(This article belongs to the Special Issue Frontiers Research in Stroke: Cortical Biomarkers Based on the Combined Use of TMS and EEG)
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