The Impact of Liquid Biopsies on Clinical Practice in Oncology
A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Clinical Medicine, Cell, and Organism Physiology".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 248
Special Issue Editors
Interests: liquid biopsy; exosomes; cancer; gastrointestinal cancer; extracellular vesicles
Special Issue Information
Dear Colleagues,
Current modalities of imaging and tissue biopsies, while essential to current tumor monitoring and characterization, have significant weaknesses that “liquid biopsies” seek to address. Liquid biopsies promise a novel approach to detecting tumor presence, growth, and recurrence. The term was first introduced with a focus on circulating tumor cells (CTCs) but has since broadened to include cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA), extracellular vesicles, exosomes, tumor-educated platelets (TEPs), and various forms of circulating RNA. While the development of liquid biopsy tools is a very active focus of research, the translation of the work for use in oncology remains an urgent need for improved patient care and the implementation of personalized treatment decision-making. The aim of this Special Issue is to highlight the work that is being carried out to develop liquid biopsies into practical clinical applications. Among other topics, we are seeking original research and review articles that elucidate the successes and weaknesses of the clinical implementation of liquid biopsies, identify biomarkers and analytes of clinically actionable cancer progression, illustrate strategies for the translation of potential liquid biopsy targets into the oncology clinic, or explore the application of liquid biopsy tools for prognostic or therapeutic guidance.
Dr. Amber Gonda
Dr. Maheswari Senthil
Guest Editors
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Keywords
- liquid biopsy
- ctDNA
- CTC
- extracellular vesicles
- exosome
- oncology
- cancer
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