Special Issue "A World Beyond Saccharomyces: Exploring Gene and Genomic Analyses to Foster Non-Conventional Yeasts As New Microbial Catalysts"

A special issue of Journal of Fungi (ISSN 2309-608X). This special issue belongs to the section "Fungal Genomics, Genetics and Molecular Biology".

Deadline for manuscript submissions: 1 March 2023 | Viewed by 338

Special Issue Editors

Prof. Dr. Nuno Pereira Mira
E-Mail Website
Guest Editor
Institute for Bioengineering and Biosciences; Instituto Superior Técnico, Department of Bioengineering; University of Lisbon, 1649-004 Lisboa, Portugal
Interests: yeasts genomics and physiology; antinfungal resistance in Candida spp; transcriptional regulatory networks
Special Issues, Collections and Topics in MDPI journals
Dr. Ana Mendes-Ferreira
E-Mail Website
Guest Editor
BioISI-Biosystems and Integrative Sciences Institute, Universidade Trás-os-Montes e Alto Douro, 5000-801 Vila Real, Portugal
Interests: differential gene expression; fermentation; Saccharomyces cerevisiae; microbiology; yeasts; enology; yeast fermentation; wine; winemaking

Special Issue Information

Dear Colleague,

Saccharomyces cerevisiae is the most paradigmatic yeast species, being a workhorse in industrial biotechnology processes of paramount importance in multiple sectors ranging from food and beverages production to the evolving field of white biotechnology. This species is also central in molecular biology studies of eukaryotic cells, being the first eukaryote cell type whose genome was fully assembled and annotated and being, till this, day a unique experimental model to study complex mechanisms of cellular biology that are difficult to examine in less genetically accessible systems (such as mammalian cells). However, more recently, it has become evident that the the Yeast’s world goes well beyond S. cerevisiae and the interest in the study of other species, usually designated as non-conventional yeasts, has been rising. This mostly regards species harbouring unique properties that are often absent in S. cerevisiae, including high resilience to industrially relevant stresses, the possibility of consuming economically attractive substrates (such as those that are renewable), and the capacity to produce compounds that are not found in the “old school” baker yeast’s metabolic repertoire. Interestingly, even species that were previously seen as bad and unwanted, frequently due to their association with spoilage processes, are valued today because of their strong potential in specific contexts such as the production of fermented beverages with improved aromatic properties. However, much is still to be learned to exploit the full potential of non-conventional yeasts, since the biology and physiology of most species are poorly studied and, in many cases, their genomic sequence is not even available. This Special Issue is focused on the genetics and genomics of non-conventional yeasts species and on how to use this knowledge to successfully explore the possibility of their application as microbial catalysts in different contexts, e.g., through metabolic engineering. Review papers concerning specific genera or species of special interest, with emphasis on the molecular players mediating their desired phenotypes, will be very welcomed for this Special Issue.

Prof. Dr. Nuno Pereira Mira
Dr. Ana Mendes-Ferreira
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Fungi is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • non-conventional yeasts
  • genomics
  • genes
  • metabolic engineering
  • microbial catalysts
  • yeast-based cell factories

Published Papers

This special issue is now open for submission.
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