Special Issue "A World Beyond Saccharomyces: Exploring Gene and Genomic Analyses to Foster Non-Conventional Yeasts As New Microbial Catalysts"
Deadline for manuscript submissions: 1 March 2023 | Viewed by 338
Interests: yeasts genomics and physiology; antinfungal resistance in Candida spp; transcriptional regulatory networks
Special Issues, Collections and Topics in MDPI journals
Interests: differential gene expression; fermentation; Saccharomyces cerevisiae; microbiology; yeasts; enology; yeast fermentation; wine; winemaking
Saccharomyces cerevisiae is the most paradigmatic yeast species, being a workhorse in industrial biotechnology processes of paramount importance in multiple sectors ranging from food and beverages production to the evolving field of white biotechnology. This species is also central in molecular biology studies of eukaryotic cells, being the first eukaryote cell type whose genome was fully assembled and annotated and being, till this, day a unique experimental model to study complex mechanisms of cellular biology that are difficult to examine in less genetically accessible systems (such as mammalian cells). However, more recently, it has become evident that the the Yeast’s world goes well beyond S. cerevisiae and the interest in the study of other species, usually designated as non-conventional yeasts, has been rising. This mostly regards species harbouring unique properties that are often absent in S. cerevisiae, including high resilience to industrially relevant stresses, the possibility of consuming economically attractive substrates (such as those that are renewable), and the capacity to produce compounds that are not found in the “old school” baker yeast’s metabolic repertoire. Interestingly, even species that were previously seen as bad and unwanted, frequently due to their association with spoilage processes, are valued today because of their strong potential in specific contexts such as the production of fermented beverages with improved aromatic properties. However, much is still to be learned to exploit the full potential of non-conventional yeasts, since the biology and physiology of most species are poorly studied and, in many cases, their genomic sequence is not even available. This Special Issue is focused on the genetics and genomics of non-conventional yeasts species and on how to use this knowledge to successfully explore the possibility of their application as microbial catalysts in different contexts, e.g., through metabolic engineering. Review papers concerning specific genera or species of special interest, with emphasis on the molecular players mediating their desired phenotypes, will be very welcomed for this Special Issue.
Prof. Dr. Nuno Pereira Mira
Dr. Ana Mendes-Ferreira
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Fungi is an international peer-reviewed open access monthly journal published by MDPI.
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- non-conventional yeasts
- metabolic engineering
- microbial catalysts
- yeast-based cell factories