Special Issue "The Diverse and Remarkable Roles of RNA in Fungi"

A special issue of Journal of Fungi (ISSN 2309-608X). This special issue belongs to the section "Fungal Genomics, Genetics and Molecular Biology".

Deadline for manuscript submissions: 31 December 2021.

Special Issue Editors

Prof. Dr. Joshua D. Nosanchuk
E-Mail Website
Guest Editor
Departments of Medicine (Division of Infectious Diseases) and Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY, USA
Interests: Dr. Nosanchuk is an expert in infectious diseases with a focus on medical mycology. He has been studying the pathogenesis of diverse fungi for over 25 years.
Dr. Lysangela R. Alves
E-Mail Website
Guest Editor
Carlos Chagas Institute, Fiocruz, Curitiba, PR 81310-020, Brazil
Interests: RNA molecules and RNA-binding proteins and the role they play in gene expression regulation in infectious diseases

Special Issue Information

Dear Colleagues,

RNA molecules are involved in a remarkable variety of important functions in the cell. From transcription to translation, different types of RNAs are involved. This Special Issue focuses on the roles of these molecules in fungal cells, from communication to antifungal response and sexual development. The investigations of mRNAs in gene expression regulation and the ncRNAs, especially the small regulatory RNAs, that are present in many fungal species are a rich area for exploration, and there is still much knowledge to be gained in this exciting field that will provide profound insights into the pathogenesis of diseases and reveal new strategies to combat mycoses. 

Prof. Dr. Joshua Nosanchuk
Dr. Lysangela R. Alves
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Fungi is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • mRNAs
  • ncRNAs
  • small RNAs
  • gene expression regulation

Published Papers (1 paper)

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Research

Article
A New Double-Stranded RNA Mycovirus in Cryphonectria naterciae Is Able to Cross the Species Barrier and Is Deleterious to a New Host
J. Fungi 2021, 7(10), 861; https://doi.org/10.3390/jof7100861 - 14 Oct 2021
Cited by 1 | Viewed by 413
Abstract
Cryphonectria is a fungal genus associated with economically significant disease of trees. Herein we characterized a novel double-stranded RNA virus from the fungal species Cryphonectria naterciae, a species unexplored as a virus host. De novo assembly of RNA-seq data and Sanger sequencing [...] Read more.
Cryphonectria is a fungal genus associated with economically significant disease of trees. Herein we characterized a novel double-stranded RNA virus from the fungal species Cryphonectria naterciae, a species unexplored as a virus host. De novo assembly of RNA-seq data and Sanger sequencing of RACE (rapid amplification of cDNA ends) clones gave the complete, non-segmented genome (10,164 bp) of the virus termed Cryphonectria naterciae fusagravirus (CnFGV1) that was phylogenetically placed within the previously proposed viral family Fusagraviridae. Of 31 field-collected strains of C. naterciae, 40% tested CnFGV1-positive. Cocultivation resulted in within-species transmission of CnFGV1 to virus-free strains of C. naterciae. Comparison of the mycelium phenotype and the growth rate of CnFGV1-infected and virus-free isogenic strains revealed frequent sectoring and growth reduction in C. naterciae upon virus infection. Co-culturing also led to cross-species transmission of CnFGV1 to Cryphonectria carpinicola and Cryphonectria radicalis, but not to Cryphonectria parasitica. The virus-infected C. naterciae and the experimentally infected Cryphonectria spp. readily transmitted CnFGV1 through asexual spores to the next generation. CnFGV1 strongly reduced conidiation and in some cases vegetative growth of C. carpinicola, which is involved in the European hornbeam disease. This study is the first report of a fusagravirus in the family Cryphonectriaceae and lays the groundwork for assessing a hypovirulence effect of CnFGV1 against the hornbeam decline in Europe. Full article
(This article belongs to the Special Issue The Diverse and Remarkable Roles of RNA in Fungi)
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