Advanced Functional and Tunable Nano-Systems for High-Performance Theranostic and Tissue Engineering Applications

Dear Colleagues,

Significant advances have been made in the field of nanotechnology, with a spectrum of nanostructures from inorganic to organic nanoformulations being designed for a range of biomedical applications to improve the efficiency and efficacy of the payload. By carefully tuning the chemical makeup of these nanostructures to their shape and size, one can precisely control the biological performance under in vitro and in vivo conditions. Different nanoparticulate systems are being developed to serve as carriers for bioactive payloads, which can then be delivered to the target site, or providing nanoscale topographical cues on the scaffold for mimicking the hierarchical organization of the tissue. The payload carried within these surface-engineered nanoparticle-based formulations ranges from delivering drugs or nucleic acids for disease treatment, antimicrobial agents in order to prevent infection, to growth factors for tissue regeneration. Additionally, significant advances have been made in the design of novel systems for achieving multiple functions such as disease diagnosis and precision therapy via targeted drug delivery systems. Significant efforts are being made on modifying synthesized nano-systems to maximize their therapeutic and diagnostic effects. This includes, but is not limited to, tuning their solubility, toxicity, degradability, cargo release profile, and biodistribution.

This Special Issue is focused on the recent advancements made in developing multifunctional nanoparticulate systems for diagnostic, therapeutic, and tissue engineering applications. We invite authors to submit original research or review articles focusing on the synthesis, surface modification, and biomedical application of nanostructures.

Topics of interest to this Special Issue include, but are not limited to:

1. Engineering nanoparticle systems for disease targeting, imaging, and/or therapeutics.
2. Organic or inorganic nanoparticles designed to control cellular response.
3. Multifaceted bioactive nanostructures with antibacterial and/or immunomodulatory properties.
4. Responsive nanostructures for tailored release of the payload at the targeted site.
5. Surface modification strategies to improve nanostructure stability and bioavailability.
6. Micro/nanoparticle coatings or formulations for disease monitoring, management, and/or treatment.

Dr. Ajeet Kaushik
Dr. Isha Mutreja
Dr. Dhiraj Kumar
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Nanotheranostics is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.