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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Measuring Recovery After Arthroplasty: Optimal Tools and Timing of Outcome Assessment submission deadline 15 Jul 2026 | Viewed by 46 | Submission Open
Keywords: arthroplasty; hip; knee; recovery; outcomes; assessment
(This special issue belongs to the Section Orthopedics)
Neurosurgery Advancements: Techniques and Patient Outcomes
edited by Vianney Gilard
submission deadline 15 Jul 2026 | Viewed by 38 | Submission Open
Keywords: neurosurgery; minimally invasive surgery; endoscopic spine surgery; intraoperative imaging; neuro-oncology; functional neurosurgery; neurovascular surgery; patient outcomes
(This special issue belongs to the Section Clinical Neurology)
Current Challenges and Advancements in Stroke Prevention and Cerebrovascular Disorders
edited by and Sylwia Krzemińska
submission deadline 15 Jul 2026 | Viewed by 35 | Submission Open
Keywords: risk factors; secondary prevention; health education; health behaviors
(This special issue belongs to the Section Clinical Rehabilitation)
Total Hip Arthroplasty Today: Trends, Challenges, and Future Directions
edited by
submission deadline 15 Jul 2026 | Viewed by 35 | Submission Open
Keywords: complex hip arthroplasty; surgical technique; innovative implant; new technology; robotic surgery; navigation surgery; artificial intelligence; complications; periprosthetic joint infection; periprosthetic fracture; dislocation
(This special issue belongs to the Section Orthopedics)
Multiple Sclerosis: Current Diagnosis, Treatment, and Future Options
edited by Przemysław Puz, and
submission deadline 15 Jul 2026 | Viewed by 33 | Submission Open
Keywords: multiple sclerosis; magnetic resonance imaging (MRI); remyelination; biomarkers; neuroprotection
(This special issue belongs to the Section Clinical Neurology)
Understanding Dermatitis: Symptoms and Effective Treatment Options
edited by and Shinichi Imafuku
submission deadline 15 Jul 2026 | Viewed by 33 | Submission Open
Keywords: dermatitis; atopic dermatitis; psoriasis; prurigo; JAK inhibitors; real world data
(This special issue belongs to the Section Dermatology)
Glaucoma: Advances in Diagnosis, Management, and Vision Preservation submission deadline 15 Jul 2026 | Viewed by 28 | Submission Open
Keywords: glaucoma diagnosis; OCT and OCT angiography; laser therapies (SLT; micropulse; cyclophotocoagulation; etc.); minimally invasive glaucoma surgery (MIGS); long-tube devices; artificial intelligence and imaging; pharmacological therapy; visual field and retinal ganglion cell function
(This special issue belongs to the Section Ophthalmology)
Novel Therapeutic Strategies in Rheumatoid Arthritis
edited by Mislav Radić
submission deadline 15 Jul 2026 | Viewed by 9 | Submission Open
Keywords: rheumatoid arthritis; targeted therapies; biological agents; small molecule inhibitors; biomarkers; personalized medicine; treatment response
(This special issue belongs to the Section Immunology & Rheumatology)
Clinical Updates in Fractures: Orthopedics, Trauma Surgery, and Rehabilitation
edited by
submission deadline 20 Jul 2026 | 1 articles | Viewed by 384 | Submission Open
Keywords: orthopedic surgery; global orthopedic health; surgical techniques; outreach; inreach; artificial intelligence; robotics; outcome measures
(This special issue belongs to the Section Orthopedics)
Minimally Invasive Spine Surgery: Evidence, Advances and Controversies
edited by , Constantine Constantoyannis, and Oliver Lasry
submission deadline 20 Jul 2026 | Viewed by 218 | Submission Open
Keywords: spine surgery; minimally invasive; MIS; MISS; endoscopic; tubular; fusion; laminectomy; discectomy; decompression; percutaneous; robotic; robotic-assisted; navigation; augmented-reality
(This special issue belongs to the Section Clinical Neurology)
Current Challenges in Adult Congenital Heart Diseases submission deadline 20 Jul 2026 | Viewed by 120 | Submission Open
Keywords: adult congenital heart disease; quality of life; pregnancy in congenital heart disease; heart failure; arrhythmia; septal defect; congenital valve stenosis; coarctation of the Aorta; Fontan circulation; Tetralogy of Fallot
(This special issue belongs to the Section Cardiology)
Current Concepts in Melanoma: Innovations in Early Detection, Prognosis and Management
edited by Babar Khan Rao
submission deadline 20 Jul 2026 | Viewed by 118 | Submission Open
Keywords: melanoma; early detection; non-invasive diagnostic innovations; artificial intelligence-assisted diagnosis; melanoma management
(This special issue belongs to the Section Dermatology)
Exercise for Healthy Aging: Clinical Physiology, Functional Outcomes, and Implications for Clinical Practice submission deadline 20 Jul 2026 | Viewed by 101 | Submission Open
Keywords: exercise; healthy aging; functional independence; mitochondrial adaptations; physical activity interventions; neuromuscular function; cardiorespiratory fitness; metabolic health; biomarkers of aging
(This special issue belongs to the Section Sports Medicine)
Pre-Hospital and In-Hospital Emergency Care Research
edited by , and Yohei Okada
submission deadline 20 Jul 2026 | Viewed by 87 | Submission Open
Keywords: pre-hospital; in-hospital; emergency care; emergency medical services; acute care
(This special issue belongs to the Section Emergency Medicine)
Integrating Artificial Intelligence into Plastic, Reconstructive, and Aesthetic Surgery: Innovations, Challenges, and Clinical Application submission deadline 20 Jul 2026 | Viewed by 69 | Submission Open
Keywords: plastic; reconstructive; aesthetic surgery; artificial intelligence; AI in plastic surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Cataract and Refractive Surgery, and Intraocular Lens (IOL) Implantation: Advancing Diagnosis and Management
edited by Olga Reitblat
submission deadline 20 Jul 2026 | Viewed by 68 | Submission Open
Keywords: cataract surgery; premium intraocular lenses (IOLs); IOL power calculation; visual outcomes; refractive cataract surgery; multifocal IOL; extended depth of focus (EDOF) IOL; toric IOL; full range; vision IOL; biometry
(This special issue belongs to the Section Ophthalmology)
Management of Diabetes-Related Cardiovascular Disease: Current Treatment and Future Options
edited by Antonio J. Amor and Tonet Serés-Noriega
submission deadline 20 Jul 2026 | Viewed by 67 | Submission Open
Keywords: type 1 diabetes; type 2 diabetes; cardiovascular disease; biomarkers; atherosclerosis; cardioprotective drugs; vascular ultrasound
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Application of Digital Transformation in Ophthalmology
edited by
submission deadline 20 Jul 2026 | Viewed by 57 | Submission Open
Keywords: clinical application; ocular diseases; artificial intelligence (AI); machine learning/ deep learning; smart ophthalmology
(This special issue belongs to the Section Ophthalmology)
Current Updates on Pediatric Neurological Disorders and Neurorehabilitation submission deadline 20 Jul 2026 | Viewed by 56 | Submission Open
Keywords: child neurological disorders; neurorehabilitation; neurogenetics; treatment; quality of life; rehabilitation teams; congenital brain disorders; trauma; movement disorders; cerebral palsy
(This special issue belongs to the Section Clinical Pediatrics)
Pneumonia: From Diagnosis to Treatment submission deadline 20 Jul 2026 | Viewed by 56 | Submission Open
Keywords: pneumonia; diagnosis; treatment; multidisciplinary care; pulmonary rehabilitation
(This special issue belongs to the Section Respiratory Medicine)
Clinical Implications of Artificial Intelligence in Patient Care
edited by and
submission deadline 20 Jul 2026 | Viewed by 54 | Submission Open
Keywords: artificial intelligence; clinical decision support; human factors; digital health; patient care; implementation science; medical informatics; trust in AI
(This special issue belongs to the Section Clinical Research Methods)
Clinical Recent Advances in the Surgical Treatment of Heart Valve Disease
edited by and Aleksander Dokollari
submission deadline 20 Jul 2026 | Viewed by 54 | Submission Open
Keywords: heart valve surgery; prosthetic valves; intervention surgery; minimally invasive and robotic surgery; valve repair and replacement
(This special issue belongs to the Section Cardiology)
Thoracic Surgery Today: Innovations, Challenges, and Future Perspectives
edited by Jeffrey B. Velotta and
submission deadline 20 Jul 2026 | Viewed by 53 | Submission Open
Keywords: thoracic surgery; minimally invasive thoracic surgery; innovation; esophageal surgery; robotic-assisted thoracic surgery; lung cancer; advanced techniques; thoracic surgical oncology; mediastinal surgery; mesothelioma surgery
(This special issue belongs to the Section General Surgery)
Sarcopenia, Musculoskeletal, and Neuromuscular Disorders: Physical Therapy and Rehabilitation Perspectives submission deadline 20 Jul 2026 | Viewed by 52 | Submission Open
Keywords: sarcopenia; musculoskeletal diseases; neuromuscular disorders; muscle mass; low back pain; neck pain; gait and balance; physical therapy; rehabilitation medicine
(This special issue belongs to the Section Clinical Rehabilitation)
New Perspective of Oral and Maxillo-Facial Surgery:2nd Edition
edited by , and Alessandra Lucchese
submission deadline 20 Jul 2026 | Viewed by 51 | Submission Open
Keywords: maxillofacial surgery; esthetic surgery; orthognatic surgery; TMJ disorders; TMJ surgery; dental implant surgery; 3D imaging; printing applications; tissue engineering; personalized treatment planning; artificial intelligence; squamous cell carcinoma; skin tumors; plastic and reconstructive surgery; head and neck surgery; ENT surgery
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Optimizing Outcomes in Pancreato-Biliary Care: Integrating Technology, Technique, and Personalized Approaches
edited by
submission deadline 20 Jul 2026 | Viewed by 51 | Submission Open
Keywords: pancreato-biliary care; pancreatic diseases; biliary diseases; hepato-pancreato-biliary (HPB) surgery; interventional endoscopy; interventional radiology; minimally invasive surgery; EUS-guided procedures; ERCP; personalized care/personalized medicine; multidisciplinary care; clinical outcomes; robotics and AI in PB care
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
State of the Art in Spinal Cord Injuries: Clinical Rehabilitation and Management
edited by
submission deadline 20 Jul 2026 | Viewed by 50 | Submission Open
Keywords: neurorehabilitation; assistive technologies; neuroplasticity; neuromodulation; spinal cord injury
(This special issue belongs to the Section Clinical Rehabilitation)
Spine Surgery: Clinical Advances and Practice Updates
edited by
submission deadline 20 Jul 2026 | Viewed by 48 | Submission Open
Keywords: spine surgery; minimally invasive spine surgery; endoscopic spine surgery; robotics; artificial intelligence; spinal deformity; scoliosis; spinal trauma
(This special issue belongs to the Section Orthopedics)
Advances in the Management of Cough and Asthma
edited by Ebymar Arismendi
submission deadline 20 Jul 2026 | Viewed by 47 | Submission Open
Keywords: asthma; chronic cough; biomarkers; exacerbations; biologics; precision medicine; airway inflammation; pediatric asthma
(This special issue belongs to the Section Respiratory Medicine)
Outcomes in Pediatric Neurosurgery
edited by and Konstantina Svokos
submission deadline 20 Jul 2026 | Viewed by 47 | Submission Open
Keywords: functional outcomes; pediatric neurosurgery; quality of life; innovative technologies; global neurosurgery
(This special issue belongs to the Section Clinical Pediatrics)
Orthodontic Treatment in Clinical Practice: Strategies for Achieving Optimal Outcomes
edited by Adith Venugopal
submission deadline 20 Jul 2026 | Viewed by 45 | Submission Open
Keywords: orthodontics; biomechanics; tooth movement; bone remodeling; malocclusions; smile
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Novel Research in Cardiovascular Imaging
edited by Stanciu Silviu and
submission deadline 20 Jul 2026 | Viewed by 44 | Submission Open
Keywords: echocardiography; cardiac CT; CMR; nuclear medicine; artificial intelligence
(This special issue belongs to the Section Cardiovascular Medicine)
Current Advances and Future Perspectives in Cardiothoracic Surgery
edited by Tomislav Kopjar
submission deadline 20 Jul 2026 | Viewed by 43 | Submission Open
Keywords: cardiothoracic surgery; minimally invasive techniques; robotic-assisted surgery; personalized therapy; surgical innovation; prosthetic devices; perioperative management; transplantation; technological advances; postoperative care; surgical outcomes; future perspectives; healthcare disparities
(This special issue belongs to the Section General Surgery)
Clinical Outcomes in Lumbar Spinal Stenosis Treatment
edited by Rafał Staszkiewicz and
submission deadline 20 Jul 2026 | Viewed by 43 | Submission Open
Keywords: lumbar spinal stenosis; clinical outcomes; decompression surgery; conservative management; molecular biomarkers; inflammation and fibrosis; neurotrophic factors; personalized medicine; siganling pathways; quality of life
(This special issue belongs to the Section Orthopedics)
Cardiac Imaging: Emerging Techniques and Clinical Applications submission deadline 20 Jul 2026 | Viewed by 42 | Submission Open
Keywords: 3D echocardiography; myocardial strain; artificial intelligence; automated quantification; cardiac MRI; cardiac CT; multimodality imaging; machine learning; image-based risk stratification; precision cardiology
(This special issue belongs to the Section Cardiology)
Applications of Artificial Intelligence and Digital Therapeutics in Clinical Medicine: 2nd Edition
edited by
submission deadline 20 Jul 2026 | Viewed by 41 | Submission Open
Keywords: artificial intelligence; biometric sensors; deep learning; digital therapies; Internet of Things; machine learning; virtual reality; augmented reality
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Clinical Medicine)
Clinical Advances in Chronic Lymphocytic Leukemia: Focus on Elderly Frail Patients
edited by Driss Chaoui
submission deadline 20 Jul 2026 | Viewed by 39 | Submission Open
Keywords: CLL; elderly; frailty; guidelines; quality of life; IBTK; BCL2; antiCD20
(This special issue belongs to the Section Hematology)
New Clinical Insight: From Open Surgery to Minimally Invasive Foot and Ankle Surgery
edited by Enrique A. Testa and Daniel Poggio
submission deadline 20 Jul 2026 | Viewed by 39 | Submission Open
Keywords: minimally invasive surgery; foot surgery; ankle surgery; trauma surgery; orthopedic surgery; ankle arthroscopy
(This special issue belongs to the Section Orthopedics)
Colorectal Surgery: Advances in Modern Clinical Management
edited by Algimantas A. Tamelis
submission deadline 20 Jul 2026 | Viewed by 38 | Submission Open
Keywords: colorectal cancer management; surgery; complications; organ preservation; screening; colonic diverticular disease; colonic diverticulitis; hemorrhoids
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Lower Limb Trauma and Orthopedic Surgery: From Bench to Bedside
edited by and
submission deadline 20 Jul 2026 | Viewed by 37 | Submission Open
Keywords: lower limb trauma; fracture fixation; arthroplasty; biomechanics; orthopaedic surgery; translational research; clin-ical outcomes; minimally invasive techniques; rehabilitation
(This special issue belongs to the Section Orthopedics)
Orthodontics: Current Management and Future Options
edited by Arūnas Vasiliauskas and Aistė Kavaliauskienė
submission deadline 20 Jul 2026 | Viewed by 35 | Submission Open
Keywords: digital orthodontics; clear aligner therapy; accelerated tooth movement; micro-implants; artificial intelligence; patient-centred outcomes; treatment efficiency
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Contactless Magnetocardiography and Related Novel Methods for Non-Invasive Experimental and Clinical Functional Imaging of Normal and Abnormal Cardiac Electrophysiology submission deadline 20 Jul 2026 | Viewed by 33 | Submission Open
Keywords: magnetocardiography; non-invasive functional imaging of cardiac electrophysiology; arrhythmogenic mechanisms; atrial fibrillation; magnetoionography; antiarrhythmic drugs; artificial intelligence
(This special issue belongs to the Section Cardiology)
Clinical Updates on Application of Echocardiography
edited by Aydan Ewers
submission deadline 20 Jul 2026 | Viewed by 33 | Submission Open
Keywords: echocardiography; heart failure; cardiomyopathies; cardiac echocardiography; interventional cardiology; cardiac imaging; pulmonary hypertension
(This special issue belongs to the Section Cardiology)
Gynecologic Cancers: Current Clinical Management and Multidisciplinary Treatment Strategies submission deadline 20 Jul 2026 | Viewed by 32 | Submission Open
Keywords: gynecologic; cancer; uterus; ovarian; endometrial; cervical
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Interventional Cardiology: From Access to Outcomes
edited by James Cotton and Benjamin Wrigley
submission deadline 20 Jul 2026 | Viewed by 32 | Submission Open
Keywords: interventional cardiology; acute coronary syndrome; chronic coronary syndrome; TAVI; TAVR; TEER; TMVR; T-TEER; TTVR; service redesign
(This special issue belongs to the Section Cardiology)
Sarcopenia: Prevention and Treatment Options
edited by Steven Phu
submission deadline 20 Jul 2026 | Viewed by 30 | Submission Open
Keywords: sarcopenia; skeletal muscle; ageing; falls; frailty; exercise; rehabilitation; nutrition
(This special issue belongs to the Section Geriatric Medicine)
Acute Coronary Syndrome(ACS): From Emergency Intervention to Long-Term Prevention
edited by Marco Ciardetti and Alessio Mattesini
submission deadline 20 Jul 2026 | Viewed by 29 | Submission Open
Keywords: acute coronary syndrome; primary percutaneous coronary intervention; antithrombotic therapy; secondary prevention; risk stratification
(This special issue belongs to the Section Cardiology)
Clinical Updates on Anesthesia and Perioperative Medicine
edited by Béla Fülesdi and
submission deadline 20 Jul 2026 | Viewed by 29 | Submission Open
Keywords: anesthesia; perioperative complications; residual neuromuscular block; postoperative pulmonary complications; intensive care unit acquired weakness; intensive care medicine; airway management; patient safety
(This special issue belongs to the Section Anesthesiology)
Hypertrophic Cardiomyopathy: New Insights into Complications and Treatment
edited by Ilaria Dentamaro and Ciro Santoro
submission deadline 20 Jul 2026 | Viewed by 29 | Submission Open
Keywords: hypertrophic cardiomyopathy; complications; risk stratification; multimodality imaging; myosin inhibitors; precision medicine
(This special issue belongs to the Section Cardiology)
Targeting the Complement for the Treatment of Autoimmune and Neurodegenerative Diseases of the Central Nervous System
edited by Charalampos Skarlis, and
submission deadline 20 Jul 2026 | Viewed by 29 | Submission Open
Keywords: complement; biologics; monoclonal antibodies; neurodegenerative diseases; CNS autoimmune diseases
(This special issue belongs to the Section Clinical Neurology)
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