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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Drug-Related Problems: Clinical Pharmacy and Safety of Pharmacotherapy

edited by

Mariola Drozd

and

Jakub Pawlikowski

submission deadline 15 Feb 2026 | 1 articles | Viewed by 1581 | Submission Open

Keywords: adverse drug reaction; drug-related problems; drug formulation technology; safety of pharmacotherapy; clinical pharmacy; pharmaceutical care; pharmacology

(This special issue belongs to the Section Pharmacology)

New Insights in Neonatal Intensive Care

edited by

Benjamim Ficial

Leonardo Gottin

and Martina Ciarcià

submission deadline 15 Feb 2026 | 1 articles | Viewed by 1052 | Submission Open

Keywords: neonatal intensive care; neonatal diseases; critically ill infants; premature infants; neonatal care; intensive care medicine

(This special issue belongs to the Section Clinical Pediatrics)

Clinical Diagnosis and Surgical Strategies Update on Ear Disorders: 2nd Edition

edited by

Eleonora M.C. Trecca

and

Andrea Albera

submission deadline 15 Feb 2026 | 1 articles | Viewed by 275 | Submission Open

Keywords: middle ear; inner ear; endoscopic ear surgery; cholesteatoma; Meniè re’ s disease; hearing loss; robotic surgery; oto-sclerosis

(This special issue belongs to the Section Otolaryngology)

Advances in Traumatic Brain Injury: Causes and Recovery

edited by Antonio Bonora

submission deadline 15 Feb 2026 | Viewed by 258 | Submission Open

Keywords: mild traumatic brain injury; TBI; brain injuries; neuroimaging; rehabilitation

(This special issue belongs to the Section Brain Injury)

Recent Advances in Refractive Surgery and Intraocular Lens Implantation

edited by Antonio Leccisotti

submission deadline 15 Feb 2026 | Viewed by 189 | Submission Open

Keywords: refractive surgery; intraocular lens implantation; keratectomy; cornea; ocular surgery; optical coherence tomography; laser surgery; KLEx (keratorefractive lenticule extraction); femtolasik

(This special issue belongs to the Section Ophthalmology)

Kidney Transplantation: Current Challenges and Future Perspectives: 2nd Edition

edited by Alberto Piana and Angelo Territo

submission deadline 15 Feb 2026 | Viewed by 188 | Submission Open

Keywords: kidney transplantation; urologic cancers; organ preservation; surgical challenges; donor selection; long-term outcomes; complications; post-transplant care; technology

(This special issue belongs to the Section Nephrology & Urology)

State of the Art in Bladder Cancer: Diagnostics and Treatment Strategies

edited by

Angelo Porreca

submission deadline 15 Feb 2026 | Viewed by 112 | Submission Open

Keywords: bladder cancer; photodynamic diagnosis (PDD); bladder-sparing strategies; robotic-assisted surgery; single-port robotic cystectomy; older patients; immunotherapy; intravesical therapy; bladder preservation; minimally invasive urology; advanced bladder cancer; diagnostic innovation

(This special issue belongs to the Section Nephrology & Urology)

Clinical Perspectives in Amyotrophic Lateral Sclerosis: Diagnosis, Management and Future Opportunities

edited by

Matthias Boentert

submission deadline 15 Feb 2026 | Viewed by 110 | Submission Open

Keywords: amyotrophic lateral sclerosis; early diagnosis; neuroimaging; biomarkers; treatment

(This special issue belongs to the Section Clinical Neurology)

Eosinophilic Esophagitis: Clinical Advances in Diagnosis, Treatment, and Monitoring

edited by Pierfrancesco Visaggi, Edoardo Vincenzo Savarino and

Nicola De Bortoli

submission deadline 18 Feb 2026 | 4 articles | Viewed by 6737 | Submission Open

Keywords: eosinophilic esophagitis (EoE); diagnosis ; treatment ; monitoring; disease assessment; precision medicine

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Endocrine Malignancies: Current Surgical Therapeutic Approaches: 2nd Edition

edited by

Mariarita Tarallo

Enrico Fiori

and Marco Bononi

submission deadline 18 Feb 2026 | 4 articles | Viewed by 5666 | Submission Open

Keywords: endocrine malignancies; thyroid cancer; adrenocortical cancer; parathyroid; men

(This special issue belongs to the Section Endocrinology & Metabolism)

Sepsis: Current Updates and Perspectives

edited by

Ecaterina Scarlatescu

submission deadline 20 Feb 2026 | 8 articles | Viewed by 21304 | Submission Open

Keywords: sepsis biomarkers; diagnostic tools; cytokines; inflammation; infection; antibiotherapy; blood purification; novel therapies

(This special issue belongs to the Section Intensive Care)

Traumatic Brain Injury: Emergency Management, Prevention of Secondary Injury, and Rehabilitation

edited by

Katja E. Wartenberg

and Lori Shutter

submission deadline 20 Feb 2026 | 5 articles | Viewed by 20355 | Submission Open

Keywords: traumatic brain injury; neuromonitoring; neurocritical care; neurorehabilitation; secondary injury; outcome; prognostication

(This special issue belongs to the Section Brain Injury)

Recent Developments in Gynecological Endocrinology

edited by

Błażej Męczekalski

submission deadline 20 Feb 2026 | 8 articles | Viewed by 20244 | Submission Open

Keywords: amenorrhea; puberty; PCOS; premature ovarian insufficiency; endometriosis; infertility; pregnancy; hormones; menopause

(This special issue belongs to the Section Obstetrics & Gynecology)

Sexually Transmitted Infections as a Challenge of Modern Society: Old Problems and Modern Solutions

edited by Mauro Zaccarelli and

Alessandra Latini

submission deadline 20 Feb 2026 | 6 articles | Viewed by 17508 | Submission Open

Keywords: sexually transmitted infections (STIs); human papilloma virus (HPV); syphilis; gonorrhea; chlamydia trachomatis; HIV infection; PrEP; chemsex

(This special issue belongs to the Section Infectious Diseases)

Endodontic and Periodontal Medicine: Systemic Implications of Oral Infections

edited by

Juan J. Segura-Egea

and

Daniel Cabanillas-Balsera

submission deadline 20 Feb 2026 | 10 articles | Viewed by 17043 | Submission Open

Keywords: dentistry; endodontics; apical periodontitis; endodontic medicine; periodontal disease; periodontal medicine; pulpitis; systemic diseases; root canal treatment

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Blood Disorders: Diagnosis, Management, and Future Opportunities

edited by

Cristina Panuzzo

and

Barbara Pergolizzi

submission deadline 20 Feb 2026 | 4 articles | Viewed by 14587 | Submission Open

Keywords: blood disorders; biomarkers; personalized medicine; diagnosis; NGS; metabolomics; digital droplet PCR (ddPCR)

(This special issue belongs to the Section Hematology)

Pediatric Critical Care: Clinical Recognition, Management, and Outcomes

edited by Janet Hume

submission deadline 20 Feb 2026 | 6 articles | Viewed by 13932 | Submission Open

Keywords: pediatric critical care medicine; sepsis; pediatric acute respiratory distress syndrome; mechanical ventilation; renal replacement therapy; chronic critical illness; post-intensive care syndrome

(This special issue belongs to the Section Clinical Pediatrics)

Cystic Fibrosis: Diagnosis and Treatment

edited by Corrado Tagliati and Gian Marco Giuseppetti

submission deadline 20 Feb 2026 | 6 articles | Viewed by 13802 | Submission Open

Keywords: cystic fibrosis; diagnosis; treatment; management

(This special issue belongs to the Section Respiratory Medicine)

Preeclampsia and Other Pregnancy Complications: Early Intervention, Diagnosis and Management

edited by

Kornelia Zaręba

Aneta Słabuszewska-Jóźwiak

and Mohamed Ahmed Mostafa Aboellail

submission deadline 20 Feb 2026 | 5 articles | Viewed by 11625 | Submission Open

Keywords: preeclampsia; pregnancy complications; early intervention; diagnosis of pregnancy complications; management of pregnancy complications; sexual dysfunctions in pregnancy

(This special issue belongs to the Section Obstetrics & Gynecology)

Orthopedic Surgery: Recent Advances and Prospects

edited by Mitchell K. Ng

submission deadline 20 Feb 2026 | 4 articles | Viewed by 10420 | Submission Open

Keywords: orthopedic surgery; clinical updates; joint reconstruction; spine surgery; trauma; elective surgery; peri-operative management

(This special issue belongs to the Section Orthopedics)

Management of Pituitary Tumors: Current and Future Treatment Options—2nd Edition

edited by

Amit Akirov

submission deadline 20 Feb 2026 | 6 articles | Viewed by 10136 | Submission Open

Keywords: pituitary; cushing syndrome; acromegaly; prolactinoma; non-functioning pituitary adenoma; hypopituitarism; hypophysitis

(This special issue belongs to the Section Endocrinology & Metabolism)

Neuroendocrine Tumors: Challenges and Future Perspectives (Second Edition)

edited by

Anna La Salvia

and

Giuseppe Lamberti

submission deadline 20 Feb 2026 | 6 articles | Viewed by 9839 | Submission Open

Keywords: neuroendocrine tumors; clinical challenges; innovative biomarkers; novel agents; personalized oncology

(This special issue belongs to the Section Oncology)

Navigating Pregnancy and Its Complications: Challenges and Innovations in Maternal–Fetal Medicine

edited by

Nikolaos Machairiotis

submission deadline 20 Feb 2026 | 3 articles | Viewed by 9113 | Submission Open

Keywords: pregnancy; obstetrics; diabetes; high risk; preeclampsia; labor; delivery; hypertension; hemorrhage; embryo; screening

(This special issue belongs to the Section Obstetrics & Gynecology)

Targeted Treatment in Chronic Inflammatory Arthritis

edited by

Cinzia Rotondo

Simone Parisi

and Simone Perniola

submission deadline 20 Feb 2026 | 4 articles | Viewed by 9028 | Submission Open

Keywords: rheumatoid arthritis; psoriatic arthritis; ankylosing spondylitis; spondyloarthritis; disease-modifying antirheumatic drugs (DMARDs); personalized medicine; immunomodulatory therapies; patient outcomes; combination therapies

(This special issue belongs to the Section Immunology & Rheumatology)

Optimizing Present and Future Therapeutic Choices for Treatment and Management of Chronic Inflammatory Bowel Diseases—2nd Edition

edited by

Lorenzo Bertani

submission deadline 20 Feb 2026 | 2 articles | Viewed by 6952 | Submission Open

Keywords: Inflammatory Bowel Diseases(IBD); JAK inhibitors; mucosal healing

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Updates on Hereditary Hemorrhagic Telangiectasia (HHT) and Other Vascular Diseases

edited by Tamás Major

submission deadline 20 Feb 2026 | 5 articles | Viewed by 6753 | Submission Open

Keywords: hereditary hemorrhagic telangiectasia (HHT); arteriovenous malformations; embolization; VEGF; capillary malformation-arteriovenous malformation

(This special issue belongs to the Section Vascular Medicine)

Innovative Approaches to the Challenges of Neurodegenerative Disease

edited by Brian T. Bicknell and

Ann Liebert

submission deadline 20 Feb 2026 | 4 articles | Viewed by 6655 | Submission Open

Keywords: neurodegenerative disease; Parkinson’ s disease; Alzheimer’ s disease; multiple sclerosis; amyotrophic lateral sclerosis

(This special issue belongs to the Section Clinical Neurology)

Novel Therapeutic Targets with Inflammatory Bowel Diseases

edited by Konstantinos H. Katsanos and

Fotios S. Fousekis

submission deadline 20 Feb 2026 | 2 articles | Viewed by 6376 | Submission Open

Keywords: inflammatory bowel disease; Crohn’ s disease; ulcerative colitis; colorectal; intestinal bowel disease; mucosal im-munology; molecular endoscopy; fibrosis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Non-Invasive Respiratory Support: Current Insights and Future Directions

edited by Giovanni Misseri and

Cesare Gregoretti

submission deadline 20 Feb 2026 | 3 articles | Viewed by 6235 | Submission Open

Keywords: respiratory failure; high-flow nasal cannula (HFNC); noninvasive ventilation (NIV); noninvasive positive pressure ventilation (NPPV); hypoxia; perioperative care; weaning; ICU; respiratory care; respiratory physiology; pneumology; home-care ventilation; artificial intelligence; personalized medicine

(This special issue belongs to the Section Respiratory Medicine)

Recent Advances in Immunotherapy of Cancer

edited by

Jessica Chacon

and

Shrikanth Gadad

submission deadline 20 Feb 2026 | 3 articles | Viewed by 6174 | Submission Open

Keywords: immunotherapy; immunology; cancer; oncology; tumor immune microenvironment; artificial intelligence; immune-related adverse events

(This special issue belongs to the Section Oncology)

Gastrointestinal Diseases: Clinical Challenges and Management

edited by Anusha Shirwaikar Thomas and

Yinghong Wang

submission deadline 20 Feb 2026 | 3 articles | Viewed by 6160 | Submission Open

Keywords: GI bleed; nutrition; obstructive jaundice; drug-induced liver injury; GI motility; clostridium difficile infection; large bowel obstruction; colon cancer prevention and surveillance

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

The Complex Interplay Between Physical Activity, Sleep, Diet, and Obesity: Clinical Insights for Treatment and Prevention

edited by

Justyna Wyszyńska

and

Piotr Matłosz

submission deadline 20 Feb 2026 | 5 articles | Viewed by 6001 | Submission Open

Keywords: body mass; body composition; nutrition; sleep patterns; weight management; lifestyle interventions; sedentary behavior; adiposity; obesity prevention; dietary habits

(This special issue belongs to the Section Clinical Rehabilitation)

Cardiopulmonary Resuscitation in Emergency Care Units

edited by

Stavros Dimopoulos

and

Christos Kourek

submission deadline 20 Feb 2026 | 4 articles | Viewed by 5622 | Submission Open

Keywords: cardiopulmonary resuscitation; emergency care; cardiac arrest; CPR techniques; resuscitation devices; post-resuscitation care; survival outcomes

(This special issue belongs to the Section Emergency Medicine)

Alcohol-Related Liver Disease: Diagnosis, Treatment, and Management

edited by

Adrian Boicean

and

Cristian Ichim

submission deadline 20 Feb 2026 | 4 articles | Viewed by 5554 | Submission Open

Keywords: alcohol-related liver disease; gut– liver axis; hepatic fibrosis; liver cirrhosis; micro-RNA; inflammatory pathways; liver transplantation; steatohepatitis; fecal microbiota transplantation in liver cirrhosis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Updates on Lumbar Spine Surgery for Degenerative Diseases

edited by

Se-Jun Park

submission deadline 20 Feb 2026 | 3 articles | Viewed by 5338 | Submission Open

Keywords: degenerative disease; lumbar spine surgery; fusion; decompressive surgery; sagittal alignment; complications; outcomes

(This special issue belongs to the Section Orthopedics)

Clinical Advances in Gastrointestinal Inflammation

edited by

Ivana Jukic

submission deadline 20 Feb 2026 | 3 articles | Viewed by 4972 | Submission Open

Keywords: Helicobacter pylori; antibiotic resistance; COVID-19 pandemic; post-COVID era; inflammatory bowel diseases; acute gastrointestinal infections; SARS-COV-2 infection; celiac disease

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Interstitial Lung Disease: From Diagnosis to Treatment

edited by

Takeshi Saraya

and Tomohisa Baba

submission deadline 20 Feb 2026 | 2 articles | Viewed by 4805 | Submission Open

Keywords: interstitial pneumonia; diagnosis; virus infection; collagen vascular disease-related interstitial pneumonia; differen-tial diagnosis; lung sounds

(This special issue belongs to the Section Respiratory Medicine)

Clinical Trends in Cardiomyopathy

edited by Giulia Iannaccone

submission deadline 20 Feb 2026 | 1 articles | Viewed by 4336 | Submission Open

Keywords: cardiomyopathy; genetics; treatment; targeted therapy; prognosis; long-term follow up

(This special issue belongs to the Section Cardiology)

Intraocular Lenses for Cataract Surgery: Clinical Advances and Perspectives

edited by Choul Yong Park

submission deadline 20 Feb 2026 | 5 articles | Viewed by 4321 | Submission Open

Keywords: cataract surgery; intraocular lens; IOL formula; optic; complication; presbyopia; refractive

(This special issue belongs to the Section Ophthalmology)

Neurosurgery: Recent Advances and New Perspectives in Skull Base Approaches

edited by Sèbastien Froelich and Matteo De Simone

submission deadline 20 Feb 2026 | 3 articles | Viewed by 4275 | Submission Open

Keywords: skull base; neuroanatomy; tumors; augmented reality; ETOA; EEA; exoscopy; endoscopy; multi-portal approaches

(This special issue belongs to the Section Clinical Neurology)

Clinical Updates in Trauma and Emergency Medicine

edited by Yong-Soo Cho and Hyun Ho Ryu

submission deadline 20 Feb 2026 | 4 articles | Viewed by 4252 | Submission Open

Keywords: emergency medicine; epidemiology; cardiovascular disease

(This special issue belongs to the Section Emergency Medicine)

Pain Management: Current Challenges and Future Prospects

edited by Gian Marco Petroni

submission deadline 20 Feb 2026 | 4 articles | Viewed by 4131 | Submission Open

Keywords: chronic joint pain; radio frequency ablation; adipose-derived mesenchimal stem cells (ADMScs); intrarticular injection; facet joint injection with ADMScs

(This special issue belongs to the Section Anesthesiology)

Innovations in Perioperative Anesthesia: Advancing Non-Operating Room Anesthesia (NORA) and Regional Techniques

edited by Francesco Coppolino and

Vincenzo Pota

submission deadline 20 Feb 2026 | 1 articles | Viewed by 3983 | Submission Open

Keywords: perioperative medicine; non-operating room anesthesia (NORA); ultrasound-guided regional anesthesia; fascial plane blocks; postoperative pain management

(This special issue belongs to the Section Anesthesiology)

Recent Developments in Hearing and Balance Disorders: 2nd Edition

edited by

Juan Carlos Amor-Dorado

submission deadline 20 Feb 2026 | 2 articles | Viewed by 3882 | Submission Open

Keywords: ear; otology; audiology; hearing disorders; deafness; hearing loss; autoimmunity; ENT; inflammation; vertigo; imbalance

(This special issue belongs to the Section Otolaryngology)

Surgical Precision: The Impact of AI and Robotics in General Surgery

edited by Tamara M. H. Gall

submission deadline 20 Feb 2026 | 4 articles | Viewed by 3768 | Submission Open

Keywords: robotic surgery; artificial intelligence in surgery; surgical training; AR in surgery; 3D imaging; surgical navigation

(This special issue belongs to the Section General Surgery)

Clinical Progress of Spine Surgery

edited by

Edoardo Mazzucchi

and Gianluca Vadalà

submission deadline 20 Feb 2026 | 2 articles | Viewed by 3654 | Submission Open

Keywords: spine surgery; rehabilitation; robotic surgery; spinal endoscopy; spinal tumor; back pain; minimally invasive surgery; spinal fusion

(This special issue belongs to the Section Clinical Neurology)

Colorectal Surgery: Innovative Techniques and Enhanced Patient Outcomes

edited by Filippo Carannante and Leandro Siragusa

submission deadline 20 Feb 2026 | 3 articles | Viewed by 3520 | Submission Open

Keywords: colorectal surgery; minimally invasive techniques; artificial intelligence; perioperative patient management; translational research in coloproctology

(This special issue belongs to the Section General Surgery)

New Perspectives in Acute Coronary Syndrome

edited by Makoto Natsumeda

submission deadline 20 Feb 2026 | 2 articles | Viewed by 3507 | Submission Open

Keywords: acute coronary syndrome; PCI; interventional cardiology; coronary imaging; antiplatelet therapy; stentless PCI strategy; CABG; revascularization

(This special issue belongs to the Section Cardiology)

Acute Kidney Events in Intensive Care Patients

edited by Kada Klouche

submission deadline 20 Feb 2026 | 2 articles | Viewed by 3413 | Submission Open

Keywords: acute kidney events; ICU; critically ill; RRT; outcome; acute kidney disease; chronic kidney disease; bi-omarkers

(This special issue belongs to the Section Intensive Care)

Kidney Transplantation: State of the Art Knowledge

edited by

Georgios Koimtzis

, Georgios Geropoulos and Kyriakos Psarras

submission deadline 20 Feb 2026 | 2 articles | Viewed by 3179 | Submission Open

Keywords: kidney transplantation; end-stage renal disease; immunosuppression; organ donation; graft survival; graft rejection

(This special issue belongs to the Section Nephrology & Urology)

Displaying special issue 451-500 on page 10 of 31.

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