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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Innovative Aspects in Dental Implantology and Related Clinical Research (Second Edition)

edited by

Carlo Barausse

and

Gerardo Pellegrino

submission deadline 22 Dec 2025 | Viewed by 183 | Submission Open

Keywords: dental implants; implantology; bone regeneration; implant-supported prosthesis; zygomatic implants; reconstructive surgery; pre-implant surgery; short implants

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

New Advances in Stereotactic Radiosurgery

edited by Shafak S. Aluwini

submission deadline 24 Dec 2025 | Viewed by 315 | Submission Open

Keywords: stereotactic radiosurgery; clinical outcomes; brachytherapy; IMRT; brain metastases; arteriovenous malformations; functional disorders; radiosurgery

(This special issue belongs to the Section Oncology)

Sports Injury: Clinical Prevention and Treatment

edited by

Carlos Lago-Fuentes

, Susana Pulgar and

Nuno Leite

submission deadline 25 Dec 2025 | 4 articles | Viewed by 20556 | Submission Open

Keywords: injury prevention; team sports; talent identification; biobanding; injury burden; muscle injury; PHV

(This special issue belongs to the Section Sports Medicine)

Skin Diseases: From Diagnosis to Treatment

edited by

Anna Colagrande

submission deadline 25 Dec 2025 | 5 articles | Viewed by 16078 | Submission Open

Keywords: skin; melanoma; NMSC; CTCL; mesenchymal

(This special issue belongs to the Section Dermatology)

Pathogenesis, Diagnosis, and Management of Upper Gastrointestinal Disease

edited by

Hidekazu Suzuki

submission deadline 25 Dec 2025 | 6 articles | Viewed by 12320 | Submission Open

Keywords: esophagus; stomach; duodenum; DGBI; FGIDs; Helicobacter; eosinophilic esophagitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Technological Advances, Innovative Applications, and New Clinical Benefits of Computed Tomography

edited by

Massimo Venturini

and

Federico Fontana

submission deadline 25 Dec 2025 | 3 articles | Viewed by 10859 | Submission Open

Keywords: computed tomography (CT); spectral CT; dual-energy CT; dual-source spectral CT; dual-layer spectral CT; pho-ton-counting CT; photon-counting detector CT; spectral photon-counting CT; artificial intelligence; radiomics

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Headache: Updates on the Assessment, Diagnosis and Treatment

edited by

Ernesto Anarte-Lazo

and

Carlos Bernal-Utrera

submission deadline 25 Dec 2025 | 7 articles | Viewed by 10113 | Submission Open

Keywords: headache; migraine; tension-type headache; cervicogenic headache; therapeutic exercise

(This special issue belongs to the Section Clinical Neurology)

Targeted Treatment of Kidney Stones

edited by Carmen Gonzalez-Enguita and

Alberto Budía-Alba

submission deadline 25 Dec 2025 | 4 articles | Viewed by 9826 | Submission Open

Keywords: shockwave lithotripsy; ureteroscopy; percutaneous nephrolithotomy; laser lithotripsy; minimally invasive techniques; stone recurrence prevention

(This special issue belongs to the Section Nephrology & Urology)

Thyroid Cancer: Clinical Diagnosis and Treatment

edited by Alfred A. Simental

submission deadline 25 Dec 2025 | 5 articles | Viewed by 9719 | Submission Open

Keywords: thyroid nodule; thyroid ultrasound; radiofrequency ablation; molecular analysis; thyroid surgery

(This special issue belongs to the Section Oncology)

Clinical Epidemiology in Chronic Kidney Disease

edited by

Vincenzo Antonio Panuccio

and Claudia Torino

submission deadline 25 Dec 2025 | 7 articles | Viewed by 9623 | Submission Open

Keywords: chronic kidney disease; end-stage kidney disease; dialysis; hypertension; renal disease; clinical nephrology; chronic renal failure

(This special issue belongs to the Section Nephrology & Urology)

New Clinical Advances in Sudden Cardiac Arrest and Ventricular Arrhythmias

edited by

Simone Savastano

submission deadline 25 Dec 2025 | 5 articles | Viewed by 9030 | Submission Open

Keywords: cardiac arrest; defibrillation; ventricular tachycardia; ventricular fibrillation; catheter ablation; non-invasive ablation; neuromodulation; stellate ganglion block

(This special issue belongs to the Section Cardiology)

Anterior Cruciate Ligament (ACL): Innovations in Clinical Management

edited by Xaver Feichtinger,

Thomas Hoffelner

and Georg Brandl

submission deadline 25 Dec 2025 | 4 articles | Viewed by 8072 | Submission Open

Keywords: ACL; graft choice; ACL repair; ALL; tibial slope

(This special issue belongs to the Section Orthopedics)

Innovations in Maxillofacial Surgery

edited by

Carlos Navarro-Cuéllar

José Luis Cebríán-Carretero

and Ignacio Navarro Cuéllar

submission deadline 25 Dec 2025 | 5 articles | Viewed by 7254 | Submission Open

Keywords: orthognathic surgery; sleep apnea; 3D technologies; regenerative medicine; reconstructive surgery; facial trauma; minimally invasive surgery; oncology

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Recent Advances in Inflammatory and Infectious Skin Diseases (Second Edition)

edited by

Giulia Ciccarese

, Astrid Herzum and Paolo Romita

submission deadline 25 Dec 2025 | 4 articles | Viewed by 6722 | Submission Open

Keywords: atopic dermatitis; eczematous diseases; inflammatory skin diseases; chronic skin diseases; human herpesvirus; roseola syphilitica; psoriasis

(This special issue belongs to the Section Dermatology)

Exploring Artificial Intelligence in Precision Medicine for Gastrointestinal Diseases

edited by Vincenzo Davide Palumbo

submission deadline 25 Dec 2025 | 3 articles | Viewed by 4401 | Submission Open

Keywords: cholangiocarcinoma; biliary tree stenoses; colorectal cancer; endoscopic image analysis; IBD; gastrointestinal disorders

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Recent Research Progress in Pediatric Orthopedic Surgery

edited by

Catharina Chiari

and Madeleine Willegger

submission deadline 25 Dec 2025 | 4 articles | Viewed by 4346 | Submission Open

Keywords: pediatric orthopedics; deformity correction; pediatric hip; pediatric trauma; basic research in pediatric orthopedics; clubfoot; pediatric foot and ankle deformities; pediatric hand

(This special issue belongs to the Section Clinical Pediatrics)

Pulmonary Embolism: Clinical Advances and Future Opportunities

edited by James Horowitz

submission deadline 25 Dec 2025 | 4 articles | Viewed by 3730 | Submission Open

Keywords: pulmonary embolism; risk stratification; pulmonary embolism response teams; high risk PE; massive PE; intermediate risk PE; sub massive PE; catheter directed thrombolysis; catheter thrombectomy; catheter directed embolectomy; extra corporeal membrane oxygenation

(This special issue belongs to the Section Respiratory Medicine)

Clinical Advances in Radiation Therapy for Cancers

edited by

Rodica Maricela Anghel

Liviu Bîlteanu

and

Laura Florentina Rebegea

submission deadline 25 Dec 2025 | 2 articles | Viewed by 2982 | Submission Open

Keywords: radiation oncology; radiotherapy; cancer radiotherapy; cancer radiation therapy; radiobiology; predictive and prognostic biomarkers; cancer treatment; heavy ions radiation oncology; protontherapy; cancer biolology

(This special issue belongs to the Section Nuclear Medicine & Radiology)

New Insights in Skin Tumors: From Pathogenesis to Therapy

edited by Loredana Ungureanu and Simona C. Şenilǎ

submission deadline 25 Dec 2025 | 3 articles | Viewed by 2148 | Submission Open

Keywords: skin tumors; pathogenesis; diagnosis; personalized medicine; therapeutic strategies; dermato-oncology

(This special issue belongs to the Section Dermatology)

Clinical Aspects of Cardiac Arrhythmias and Arrhythmogenic Disorders

edited by

Piotr Bienias

and Jakub Baran

submission deadline 25 Dec 2025 | 3 articles | Viewed by 1820 | Submission Open

Keywords: non-invasive arrhythmia assessment; electrocardiography; invasive arrhythmia assessment; invasive electrophysiology; catheter ablation; implantable devices; rare diseases and arrhythmias; arrhythmia risk stratification; genetics aspects of arrhythmogenesis; channelopathy

(This special issue belongs to the Section Cardiology)

State-of-the-Art in Cardiac Surgery: Progress, Challenges and Opportunities

edited by Tomasz Plonek and Sleiman Sebastian Aboul-Hassan

submission deadline 25 Dec 2025 | 2 articles | Viewed by 1606 | Submission Open

Keywords: aorta ascendens; minimally invasive surgery; aortic arch surgery; off pump coronary surgery; arterial grafts

(This special issue belongs to the Section Cardiology)

Advances in Anterior Segment Surgery: Second Edition

edited by

Mayank A. Nanavaty

submission deadline 25 Dec 2025 | 2 articles | Viewed by 1589 | Submission Open

Keywords: lenticule-based surgery; surface ablations; blended vision treatments with laser refractive surgery; corneal inlay procedures; presbyopia management with monovision laser vision correction; refractive lens exchange; premium presbyopia-correcting intraocular lens; refractive solutions for keratoconics; cataract surgery; corneal transplant; biometry

(This special issue belongs to the Section Ophthalmology)

Innovations and Future Directions in Valvular Heart Disease: Imaging, Technology, and Translational Research

edited by

Mohammad Kassar

, Muhammed Gerçek and Felix Rudolph

submission deadline 25 Dec 2025 | 2 articles | Viewed by 881 | Submission Open

Keywords: prosthetic heart valve; heart valve pathophysiology; structural heart valve interventions; echocardiographic assessment; cardiovascular imaging; valvular heart disease; valvular regurgitation; valvular stenosis; minimally invasive surgery; concomitant valve disease

(This special issue belongs to the Section Cardiology)

Kidney Health Under Microscope

edited by

Magdi Yaqoob

submission deadline 25 Dec 2025 | Viewed by 279 | Submission Open

Keywords: complications; IgA nephropathy; glomerulonephritis; atypical haemolytic uraemic syndrome; systemic vasculitis; lupus nephritis; mineral bone disease; anaemia; xenotransplantation; nephrolithiasis

(This special issue belongs to the Section Nephrology & Urology)

Psychological Pain and Suicidal Behavior: Clinical Implications

edited by Adrián Alacreu-Crespo

submission deadline 25 Dec 2025 | Viewed by 271 | Submission Open

Keywords: suicidal behavior; psychological pain; pain tolerance; therapeutic interventions; clinical outcomes

(This special issue belongs to the Section Mental Health)

Cardiac Imaging Techniques in Heart Failure Care

edited by David Snipelisky

submission deadline 25 Dec 2025 | Viewed by 270 | Submission Open

Keywords: heart failure; advanced imaging; cardiac imaging; echocardiography; cardiomyopathies

(This special issue belongs to the Section Cardiology)

Advances and Innovations in Hand Surgery

edited by

David L. Colen

, Jason Wink and Anthony Archual

submission deadline 25 Dec 2025 | 1 articles | Viewed by 249 | Submission Open

Keywords: hand surgery; peripheral nerve surgery; shared decision making; microsurgery; arthritis; compression neuropathy; carpal tunnel; cubital tunnel

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Myocardial Infarction: Clinical Management and Future Options

edited by

Kenichi Sakakura

submission deadline 25 Dec 2025 | Viewed by 152 | Submission Open

Keywords: myocardial infarction; percutaneous coronary intervention; optimal medical therapy; clinical outcomes; cardiogenic shock; mechanical cardiac support device

(This special issue belongs to the Section Cardiology)

IgA Nephropathy: Clinical Updates and Prospects

edited by

Meritxell Ibernon

submission deadline 25 Dec 2025 | Viewed by 130 | Submission Open

Keywords: pathogenesis of IgA nephropathy; novel therapies; role of complement system; risk factors for disease progression; proteomic approach; serologic biomarkers; histological classification

(This special issue belongs to the Section Nephrology & Urology)

Cardiac Rehabilitation: Clinical Challenges and New Insights

edited by Melissa Tracy

submission deadline 26 Dec 2025 | 3 articles | Viewed by 8187 | Submission Open

Keywords: cardiovascular disease; cardiac rehabilitation; atrial fibrillation

(This special issue belongs to the Section Cardiology)

Current Clinical Treatments and Challenges for Cardiovascular Diseases

edited by Georgios Bouras and

Christos Kourek

submission deadline 26 Dec 2025 | 4 articles | Viewed by 6870 | Submission Open

Keywords: heart failure; coronary artery disease; atrial fibrillation; cardiomyopathies; hypertension

(This special issue belongs to the Section Cardiovascular Medicine)

New Advances in Extracorporeal Life Support (ECLS)

edited by Robertas Stasys Samalavičius,

Pranas Šerpytis

and

Holger Thiele

submission deadline 26 Dec 2025 | 2 articles | Viewed by 4811 | Submission Open

Keywords: extracorporeal life support (ECLS); extracorporeal membrane oxygenation (ECMO); innovations in ECLS; respiratory failure; cardiogenic shock; eCPR

(This special issue belongs to the Section Emergency Medicine)

Current Clinical Advances and Challenges for Endourology

edited by

Carlo Giulioni

and

Daniele Castellani

submission deadline 26 Dec 2025 | 2 articles | Viewed by 1486 | Submission Open

Keywords: urolithiasis; upper tract urothelial carcinoma; benign prostatic hyperplasia; minimally invasive surgical therapies

(This special issue belongs to the Section Nephrology & Urology)

Multifactorial Causation and Therapies of Myopia: 2nd Edition

edited by

César Villa Collar

Cristina Alvarez-Peregrina

and

David Piñero

submission deadline 26 Dec 2025 | 1 articles | Viewed by 901 | Submission Open

Keywords: epidemiology; genetics; premyopia; simple and pathological myopia; orthokeratology; lenses for myopia control; blue light and red light; binocular vision and ocular optics; artificial intelligence

(This special issue belongs to the Section Ophthalmology)

Clinical Updates on Metabolic and Bariatric Surgery

edited by Maria-Jose Barahona

submission deadline 27 Dec 2025 | 1 articles | Viewed by 803 | Submission Open

Keywords: obesity; bariatric surgery; metabolic surgery; weight loss; obesity treatment; metabolic disorders

(This special issue belongs to the Section General Surgery)

Atrial Fibrillation Rhythm Management: Outcomes, Innovations, and Future Directions

edited by Roberto Scacciavillani and Gemma Pelargonio

submission deadline 28 Dec 2025 | 5 articles | Viewed by 4975 | Submission Open

Keywords: atrial fibrillation; catheter ablation; radiofrequency; cryoablation; pulsed field ablation; cardioneuroablation; left bundle branch area pacing

(This special issue belongs to the Section Cardiology)

Lung Transplantation: Current Strategies and Future Directions

edited by Omer Senbaklavaci and György Lang

submission deadline 28 Dec 2025 | 1 articles | Viewed by 1474 | Submission Open

Keywords: lung transplantation; graft optimization; immunosuppression; artificial lung; xenotransplantation; end-stage lung disease; donor lung preservation; chronic lung allograft dysfunction

(This special issue belongs to the Section Respiratory Medicine)

Imaging and Molecular Biomarkers: The New Approach to Degenerative Retinal Diseases

edited by

Giulia Midena

and

Elisabetta Pilotto

submission deadline 28 Dec 2025 | 1 articles | Viewed by 455 | Submission Open

Keywords: ophthalmology; degenerative retinal diseases; imaging biomarkers; multimodal imaging; OCT; OCT angiography; molecular biomarkers; precision medicine; translational ophthalmic research

(This special issue belongs to the Section Ophthalmology)

Managements of Venous Thromboembolism

edited by

Anabel Franco Moreno

submission deadline 29 Dec 2025 | 3 articles | Viewed by 2025 | Submission Open

Keywords: venous thromboembolism; deep vein thrombosis; pulmonary embolism; anticoagulation therapy; direct oral anticoagulants; risk stratification; bleeding risk; artificial intelligence; personalized medicine

(This special issue belongs to the Section Vascular Medicine)

Pediatric Neurosurgery: Clinical Advances in Diagnostics and Perioperative Management

edited by Kara Leigh Krajewski and Ulrich-Wilhelm Thomale

submission deadline 29 Dec 2025 | 1 articles | Viewed by 895 | Submission Open

Keywords: rapid sequence MRI; intraoperative MRI; perioperative management; neurocritical care; patient selection; M&M conferences; surgical team; rehabilitation

(This special issue belongs to the Section Clinical Pediatrics)

Current Concepts and Clinical Application of Echocardiography

edited by

Marco Solari

submission deadline 29 Dec 2025 | Viewed by 161 | Submission Open

Keywords: echocardiography; clinical echocardiography; advanced echocardiography; cardiovascular disease; clinical cardiology

(This special issue belongs to the Section Cardiology)

Treatment of Atopic Dermatitis

edited by

Francisco José Navarro-Triviño

and Ricardo Ruíz-Villaverde

submission deadline 30 Dec 2025 | 6 articles | Viewed by 19821 | Submission Open

Keywords: atopic dermatitis; eczema; topical treatment; systemic treatment; biological therapy; JAK inhibitor; antipruritic treatment

(This special issue belongs to the Section Dermatology)

Chronic Pain: Non-Pharmacological Treatments and Rehabilitation Strategies

edited by Matteo Ponzano

submission deadline 30 Dec 2025 | 8 articles | Viewed by 13886 | Submission Open

Keywords: pain; neuropathies; musculoskeletal health; biopsychosocial management; physical therapy; cognitive behavioral therapies

(This special issue belongs to the Section Clinical Rehabilitation)

Clinical Perspectives on Women’s Reproductive Health: Challenges and Management Strategies

edited by

Seok Kyo Seo

submission deadline 30 Dec 2025 | 8 articles | Viewed by 11748 | Submission Open

Keywords: endometriosis; ovarian endometrioma; polycystic ovary syndrome; reproductive health; cervical; postmenopausal women; hormone replacement therapy; sarcopenia

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Challenges in Inflammatory Bowel Diseases

edited by

Wesley M. Raup-Konsavage

submission deadline 30 Dec 2025 | 4 articles | Viewed by 7498 | Submission Open

Keywords: ulcerative colitis; Chron’ s disease; inflammatory bowel disease; colitis-associated cancer; novel pharmaceutics

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

The State of Breast Reconstruction: From Surgical Methods to Patient-Reported Outcomes

edited by Geoffroy C. Sisk

submission deadline 30 Dec 2025 | 2 articles | Viewed by 4832 | Submission Open

Keywords: breast reconstruction; implant based; autologous tissue; oncoplastic; breast cancer reconstruction; patient-reported outcomes; acellular dermal matrix; prepectoral; lymphedema; microsurgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Recent Advances in Glaucoma Management

edited by Bogomil Voykov

submission deadline 30 Dec 2025 | 3 articles | Viewed by 4460 | Submission Open

Keywords: glaucoma; MIGS; microinvasive glaucoma surgery; quality of life; sustained-release drugs; wound healing modula-tion; intraocular pressure; intraocular pressure-lowering medication; microstent-supported bleb surgery; MIBS; neuroprotection

(This special issue belongs to the Section Ophthalmology)

Clinical Management for Coronary Artery Disease and Revascularization

edited by Mohammad Reza Movahed

submission deadline 30 Dec 2025 | 3 articles | Viewed by 3898 | Submission Open

Keywords: coronary artery disease; coronary syndrome; stenting; revascularization; cardiovascular

(This special issue belongs to the Section Cardiovascular Medicine)

Advancements in Emergency Medicine Practices and Protocols

edited by Vincenzo G. Menditto and Beatrice Gasperini

submission deadline 30 Dec 2025 | 4 articles | Viewed by 3750 | Submission Open

Keywords: emergency; pulmonary embolism; trauma; management; guidelines; frailty; emergency department observation unit

(This special issue belongs to the Section Emergency Medicine)

Ultrasound-Guided Biopsy of Gynecologic Tumors: Technique and Clinical Application

edited by

Athina A. Samara

and Alexandros Daponte

submission deadline 30 Dec 2025 | 1 articles | Viewed by 2252 | Submission Open

Keywords: ultrasound-guided biopsy; gynecologic tumors; ovarian cancer; biopsy technique; precision diagnosis; endometrial lesions

(This special issue belongs to the Section Obstetrics & Gynecology)

Displaying special issue 301-350 on page 7 of 31.

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