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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Advances in Trauma and Orthopaedic Surgery

edited by Valerio Pace and Pierluigi Antinolfi

submission deadline 20 Dec 2025 | 3 articles | Viewed by 3651 | Submission Open

Keywords: orthopaedic surgery; hand/wrist surgery; tendon injury; ligament injury; artificial intelligence (AI); robotic surgery; orthopaedic injections; nerve injury

(This special issue belongs to the Section Orthopedics)

Targeted Treatment of Oral Cancer

edited by

Yasmine Ghantous

and

Claudia Malheiros Coutinho-Camillo

submission deadline 20 Dec 2025 | 3 articles | Viewed by 3532 | Submission Open

Keywords: precision medicine; immunotherapy; targeted drugs; combination therapy; tumor immune evasion; clinical trials

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Anesthesia and Intensive Care in Orthopedic and Trauma Surgery

edited by Liliana Mirea, Răzvan Ene and Cristian Cobilinschi

submission deadline 20 Dec 2025 | 2 articles | Viewed by 3509 | Submission Open

Keywords: opioid sparing analgetic technique; pain management; perioperative medicine; perioperative cognitive disfunction; delirium

(This special issue belongs to the Section Intensive Care)

Advancements in Femtosecond Laser Applications

edited by Luca Schwarzenbacher, Eva Stifter and Philipp Roberts

submission deadline 20 Dec 2025 | 4 articles | Viewed by 3495 | Submission Open

Keywords: femtosecond laser; cataract surgery; DSAEK; DALK; femto-CAIRS; congenital cataract

(This special issue belongs to the Section Ophthalmology)

Clinical Management of Burns: Past, Present and Future

edited by Lior Rosenberg

submission deadline 20 Dec 2025 | 1 articles | Viewed by 3203 | Submission Open

Keywords: history of burn care; burn care infection; inflammation; burn wound care and closure; debridement; traditional Chinese burn care; traditional Indian (Ayurveda) burn care; burn mass casualty incidents (BMCIs); surge capacity; burn pain control; pruritus; burn scar treatment

(This special issue belongs to the Section General Surgery)

Maternal–Fetal Medicine: Current Status, Challenges, and Future Directions

edited by Jessian Munoz

submission deadline 20 Dec 2025 | 3 articles | Viewed by 3147 | Submission Open

Keywords: maternal– fetal medicine; preterm delivery; preterm birth management; newborn; obstetrics; high-risk pregnancy; perinatal outcome; placenta accreta; fetal surgery

(This special issue belongs to the Section Obstetrics & Gynecology)

Colorectal Surgery: Current Practice and Future Perspectives

edited by

Karel Kostev

submission deadline 20 Dec 2025 | 2 articles | Viewed by 3108 | Submission Open

Keywords: colorectal surgery; minimal invasive surgery; open surgery; robot assisted surgery; colorectal cancer; stomach cancer; pancreatic cancer; diverticular disease

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Investigations into Diagnosing and Managing Strabismus

edited by Mario Cantó Cerdán and Pilar Cacho-Martínez

submission deadline 20 Dec 2025 | 3 articles | Viewed by 3084 | Submission Open

Keywords: oculomotricity; binocular vision; strabismus; ocular motility disorders; exotropia; esotropia; video oculography; eye tracker; ocular deviation

(This special issue belongs to the Section Ophthalmology)

Diagnosis, Treatment and Comorbidities in Chronic Obstructive Pulmonary Disease (COPD): 2nd Edition

edited by Juan Luis Rodriguez Hermosa, José Luis Álvarez-Sala Walther and Myriam Calle Rubio

submission deadline 20 Dec 2025 | 3 articles | Viewed by 3067 | Submission Open

Keywords: COPD; diagnosis; comorbidities; respiratory rehabilitation; inhaled therapy; biological therapies

(This special issue belongs to the Section Respiratory Medicine)

Updates on the Clinical Applications of Dental Restorative Materials

edited by

Vittorio Checchi

submission deadline 20 Dec 2025 | 1 articles | Viewed by 2681 | Submission Open

Keywords: restorative dentistry; restorations; adhesive dentistry; resin composites; ceramics; aesthetics; dental materials; direct restorations; indirect restorations; conservative dentistry; prosthetic dentistry; partial restorations; total restorations

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Periodontitis and Other Periodontal Diseases

edited by

Giovanna Murmura

submission deadline 20 Dec 2025 | 3 articles | Viewed by 2629 | Submission Open

Keywords: periodontal diseases; gingivitis; periodontitis; systemic disease; classification

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Multiple Sclerosis: Clinical Advances in Diagnosis and Treatment

edited by

Marta Simone

submission deadline 20 Dec 2025 | 1 articles | Viewed by 2588 | Submission Open

Keywords: relapse-remitting multiple sclerosis; progressive multiple sclerosis; immunomodulatory treatments; cognitive impairment; personalized medicine in multiple sclerosis

(This special issue belongs to the Section Clinical Neurology)

Genitourinary Cancers: Clinical Advances and Practice Updates

edited by David Benjamin and Arash Rezazadeh Kalebasty

submission deadline 20 Dec 2025 | 2 articles | Viewed by 2198 | Submission Open

Keywords: rare tumors; genitourinary cancers; urachal cancer; penile cancer; testicular cancer; variant histology

(This special issue belongs to the Section Nephrology & Urology)

Clinical Management of Bladder Cancer

edited by

Antonio Franco

, Antonio Cicione and

Francesco Ditonno

submission deadline 20 Dec 2025 | 1 articles | Viewed by 2118 | Submission Open

Keywords: bladder cancer; minimally invasive surgery; immunotherapy; targeted therapy; biomarkers; imaging techniques; muscle invasive bladder cancer; non-muscle-invasive bladder cancer

(This special issue belongs to the Section Nephrology & Urology)

Clinical Innovations in Dental Implant: Expanding Possibilities for Oral Rehabilitation

edited by Marco Severino

submission deadline 20 Dec 2025 | 1 articles | Viewed by 2103 | Submission Open

Keywords: dental implants; oral rehabilitation; computer-guided surgery; biocompatibility; regenerative treatments; mini-implants; minimally invasive surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Antithrombotic Therapies for Acute Coronary Syndrome and Atrial Fibrillation

edited by

Mojca Božič Mijovski

submission deadline 20 Dec 2025 | 1 articles | Viewed by 1690 | Submission Open

Keywords: atrial fibrillation; acute coronary syndrome; antiplatelet agents; anticoagulants; thrombolysis; direct coagulation factor inhibitors; medical laboratory technology

(This special issue belongs to the Section Cardiology)

New Insights in Maxillofacial Surgery

edited by

Izumi Asahina

submission deadline 20 Dec 2025 | 1 articles | Viewed by 1517 | Submission Open

Keywords: maxillofacial surgery; surgical techniques; imaging technologies; biomaterials; regenerative medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Diagnosis and Treatment of Urological Cancers

edited by Davide Campobasso,

Stefano Puliatti

and

Daniele Amparore

submission deadline 20 Dec 2025 | 2 articles | Viewed by 1418 | Submission Open

Keywords: prostate cancer; kidney cancer; urothelial carcinoma; testis cancer; mini-invasive surgery; precision surgery; target therapy; immunotherapy; nuclear medicine; artificial intelligence; augmented reality; biomarkers; prognostic factors and models; focal therapy; radiotherapy; imaging; genetics

(This special issue belongs to the Section Nephrology & Urology)

Clinical Perspectives of Vascular and Endovascular Surgeries

edited by

Adrian Vasile Muresan

Emil Marian Arbănași

and

Eliza Russu

submission deadline 20 Dec 2025 | 2 articles | Viewed by 1276 | Submission Open

Keywords: vascular surgery; varicose veins; abdominal aortic aneurysms; carotid disease; peripheral arterial disease

(This special issue belongs to the Section Vascular Medicine)

Current Challenges and Perspectives in Liver Transplantation

edited by Bogdan Dorobanţu,

Umberto Cillo

and Waldo Concepcion

submission deadline 20 Dec 2025 | 1 articles | Viewed by 1199 | Submission Open

Keywords: liver transplantation; liver surgery; liver cirrhosis; liver disease; alcoholic and non-alcoholic steatohepatitis; cholangiocarcinoma; hepatocellular carcinoma; auxiliary liver transplantation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Key Challenges in Heart Transplantation and Their Solutions

edited by Elizabeth J. Maynes

submission deadline 20 Dec 2025 | 1 articles | Viewed by 1151 | Submission Open

Keywords: heart transplantation; heart failure; cardiac surgery; minimally invasive techniques; general surgery; heart diseases

(This special issue belongs to the Section Cardiology)

Neurological Rehabilitation: Repair Mechanisms, Plasticity, and Connectomes

edited by Thomas Mokrusch and Frank Kirchhoff

submission deadline 20 Dec 2025 | 1 articles | Viewed by 1125 | Submission Open

Keywords: neurorehabilitation; therapeutic approaches; repair mechanism; plasticity; neurology

(This special issue belongs to the Section Clinical Neurology)

Current Perspectives and Innovations in Urogynecology

edited by Stavros Athanasiou

submission deadline 20 Dec 2025 | 1 articles | Viewed by 822 | Submission Open

Keywords: urogynecology; pelvic organ prolapse; urinary incontinence; overactive bladder; pelvic floor surgery; reconstructive surgery; minimally invasive surgery; pelvic floor disorders; innovative surgical techniques; quality of life

(This special issue belongs to the Section Obstetrics & Gynecology)

New Perspectives in Maternal–Fetal Medicine

edited by Catalina de Paco-Matallana

submission deadline 20 Dec 2025 | 1 articles | Viewed by 787 | Submission Open

Keywords: maternal– fetal medicine; prenatal diagnostics; fetal therapy; precision medicine; neonatal outcomes; maternal health

(This special issue belongs to the Section Obstetrics & Gynecology)

Cardiovascular Imaging: Diagnosis and Therapeutic Guidance in Clinical Practice

edited by

Stefano Figliozzi

submission deadline 20 Dec 2025 | 1 articles | Viewed by 656 | Submission Open

Keywords: cardiovascular magnetic resonance; cardiac imaging; T1 and T2 mapping; myocardial tissue characterization; late gadolinium enhancement; ischemic heart disease; cardiomyopathies; valvular heart disease; therapeutic guidance; precision medicine; mitral valve prolapse

(This special issue belongs to the Section Cardiology)

Novel Diagnostic and Therapeutic Strategies in Vitreoretinal Disease

edited by Jerzy Mackiewicz and

Mateusz Winiarczyk

submission deadline 20 Dec 2025 | Viewed by 356 | Submission Open

Keywords: retinal detachment; vitreoretinal diseases; PPV; vitrectomy; macular edema; uveitis; AMD; retinal imaging; retinal pathology; diabetic retinopathy; optical coherent tomography; OCT

(This special issue belongs to the Section Ophthalmology)

Innovative Treatment and Management Strategies for Inflammatory Bowel Disease

edited by Syed Adeel Hassan and

Neeraj Kapur

submission deadline 20 Dec 2025 | Viewed by 318 | Submission Open

Keywords: Crohn’ s disease; ulcerative colitis; efficacy; safety; nutrition; surgery; biomarkers

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Transformative Research in Hydrocephalus: Clinical Advances

edited by Afroditi D. Lalou, Zofia Helena Czosnyka and Marek Czosnyka

submission deadline 20 Dec 2025 | Viewed by 277 | Submission Open

Keywords: cerebrospinal fluid dynamics; CSF shunt; intracranial pressure monitoring; telemetric ICP; hydrocephalus pathophysiology; neuroimaging; paediatric hydrocephalus; adult hydrocephalus; translational neuroscience

(This special issue belongs to the Section Clinical Neurology)

Risk Factors in Neonatal Intensive Care

edited by

Gabriela C. Zaharie

and

Melinda Matyas

submission deadline 20 Dec 2025 | Viewed by 269 | Submission Open

Keywords: neonatal intensive care; infant birth; preterm; neonatal resuscitation; neonatal outcome; growth restriction; prenatal diagnosis; severe maternal pathology and its effects on a newborn; therapeutical hypothermia; parenteral nutrition; neonatal infection; retinopathy of prematurity

(This special issue belongs to the Section Clinical Pediatrics)

Parkinson's Disease: Recent Advances in Diagnosis and Treatment

edited by

Mariachiara Sensi

and

Fabiana Colucci

submission deadline 20 Dec 2025 | Viewed by 254 | Submission Open

Keywords: Parkinson’ s disease; disease-modifying therapies; artificial intelligence; microbiome; alpha-synuclein; neuroimaging

(This special issue belongs to the Section Clinical Neurology)

New Clinical Advances in Breast Reconstruction

edited by

Nobuyuki Mitsukawa

submission deadline 20 Dec 2025 | Viewed by 225 | Submission Open

Keywords: breast reconstruction; autologous (flap) reconstruction; implant-based reconstruction; microsurgery and perforator flaps; robotic surgery/endoscopic surgery; fat grafting (lipofilling); patient-reported outcomes; reconstructive surgical innovation

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Applications of Artificial Intelligence in Cardiology: New Tools to Transform Care

edited by

Constantinos Bakogiannis

submission deadline 20 Dec 2025 | Viewed by 219 | Submission Open

Keywords: artificial intelligence in cardiology; machine learning; deep learning; AI-driven ECG analysis; cardiovas-cular imaging and AI; predictive analytics in cardiology; mHealth and wearables; clinical decision support systems; ethics and AI in healthcare; digital health and remote monitoring

(This special issue belongs to the Section Cardiology)

Recent Developments in Urinary Incontinence

edited by

Michael Samarinas

submission deadline 20 Dec 2025 | Viewed by 178 | Submission Open

Keywords: urinary incontinence; overactive bladder; stress urinary incontinence; pelvic floor dysfunction; urodynamics; minimally invasive treatment; neuromodulation; regenerative medicine; conservative management; digital health in urology

(This special issue belongs to the Section Nephrology & Urology)

Hospital-Acquired Infections: Insights, Prevention, and Control Strategies

edited by

Andrea Fabbri

submission deadline 20 Dec 2025 | Viewed by 169 | Submission Open

Keywords: healthcare-acquired infections; bloodstream infections; hospital‐acquired pneumonia; intestinal infections; clostridium difficile; surgical site infections; urinary tract infections; emergency department

(This special issue belongs to the Section Epidemiology & Public Health)

Surgical Oncology: Clinical Application of Translational Medicine

edited by Domenico Parmeggiani

submission deadline 20 Dec 2025 | Viewed by 164 | Submission Open

Keywords: surgical oncology; drug safety; adverse events; nanovesicles; targeted drug delivery; cancer biomarkers; precision oncology; tumor microenvironment; nanomedicine; personalized medicine; diagnostics; prognosis; innovative therapies; translational research

(This special issue belongs to the Section Oncology)

Current and Emerging Treatment Options in Intestinal and Stomach Neoplasms

edited by Alexandros E. Giakoustidis and

Ioannis Konstantinidis

submission deadline 20 Dec 2025 | Viewed by 151 | Submission Open

Keywords: colorectal cancer; colon cancer; gastric carcinoma; malignancy; gastroenterology; endoscopic techniques; therapeutic advancements; intestinal neoplasms

(This special issue belongs to the Section Oncology)

Laparoscopy and Surgery in Gynecologic Oncology: 2nd Edition

edited by Zoltan Novak

submission deadline 20 Dec 2025 | Viewed by 147 | Submission Open

Keywords: gynecologic cancers; ovarian; uterine; cervical; laparoscopy; diagnosis; staging; treatment; palliative care; fertility preservation

(This special issue belongs to the Section Obstetrics & Gynecology)

The Treatment of BPO with Minimal Invasive Approach

edited by

Lukas Lusuardi

submission deadline 20 Dec 2025 | Viewed by 141 | Submission Open

Keywords: benign prostatic obstruction (BPO); prostatectomy; non-muscle invasive bladder cancer; muscle invasive bladder cancer; robotic surgery

(This special issue belongs to the Section Nephrology & Urology)

Advanced Image-Enhanced Endoscopy and Colonoscopy

edited by

Giuseppinella Melita

Marcello F. Maida

and Simona Di Caro

submission deadline 20 Dec 2025 | Viewed by 141 | Submission Open

Keywords: gastrointestinal endoscopy; colorectal cancer; endoscopic screening; artificial intelligence; chromoendoscopy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Research and Insights in Endometriosis

edited by

Nikolaos Machairiotis

submission deadline 20 Dec 2025 | Viewed by 140 | Submission Open

Keywords: endometriosis; pelvic pain; infertility; inflammation; minimal access surgery; laparoscopy; hysteroscopy; robotics

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in Clinical Management of Temporomandibular Joint Diseases

edited by

João Luiz Monteiro

submission deadline 20 Dec 2025 | Viewed by 137 | Submission Open

Keywords: minimally invasive surgical procedure; artificial intelligence; temporomandibular joint disorders; temporomandibular disorders; temporomandibular joint

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Lung Transplantation and Interventional Pulmonology

edited by Anupam Kumar and Frye Laura

submission deadline 20 Dec 2025 | Viewed by 137 | Submission Open

Keywords: lung transplantation; interventional pulmonology; immunosuppressive therapies; organ rejection; pulmonary rehabilitation; surgical innovations; post-transplant complications; diagnostic advancements; donor lung shortage; thoracic surgery

(This special issue belongs to the Section Respiratory Medicine)

Advanced Technologies, Concepts, and Topics in Modern Neurosurgery

edited by

Samer Zawy Alsofy

and Ralf Stroop

submission deadline 20 Dec 2025 | Viewed by 132 | Submission Open

Keywords: modern neurosurgery; virtual reality; augmented reality; intraoperative imaging; neuronavigation; artificial intelligence; machine learning; robotic surgery; 3D printing; neurovascular interventions; neuro-oncology; skull base surgery; functional neurosurgery; spinal neurosurgery; surgical innovation; image-guided surgery; personalized neurosurgical planning

(This special issue belongs to the Section General Surgery)

Status, Application and Future Directions of Artificial Urinary Sphincters

edited by JiSung Shim

submission deadline 20 Dec 2025 | Viewed by 132 | Submission Open

Keywords: ISD; robot surgery; neurogenic SUI; female AUS; complication; erosion; urethroplasty; malfunction; PPI; BOO

(This special issue belongs to the Section Nephrology & Urology)

Gastric Cancer: Epidemiology, Clinical Management and Emerging Biomarkers

edited by

Akira Tsuburaya

and

Takashi Oshima

submission deadline 20 Dec 2025 | Viewed by 98 | Submission Open

Keywords: gastric cancer; metabolism; biomarkers; surgical stress; adjuvant therapy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Innovations in Preeclampsia

edited by Jeffrey M. Denney and

Liliya Yamaleyeva

submission deadline 22 Dec 2025 | 3 articles | Viewed by 13262 | Submission Open

Keywords: preeclampsia; pathophysiology; renin; SFlt-1; PlGF; hypertensive disorders of pregnancy; imitators of preeclampsia; vascular reactivity

(This special issue belongs to the Section Obstetrics & Gynecology)

Scoliosis: Advances in Diagnosis and Management

edited by Michal Latalski

submission deadline 22 Dec 2025 | 3 articles | Viewed by 3531 | Submission Open

Keywords: scoliosis; adolescent idiopathic scoliosis; adult scoliosis; congenital scoliosis; neuromuscular scoliosis; diagnosis; imaging; treatment; surgery; bracing; rehabilitation; patient-reported outcomes; quality of life

(This special issue belongs to the Section Orthopedics)

Clinical Advances of Adolescent Idiopathic Scoliosis: Current Status and Prospects

edited by Maria Chiara Maccarone and

Stefano Masiero

submission deadline 22 Dec 2025 | 2 articles | Viewed by 3452 | Submission Open

Keywords: adolescent idiopathic scoliosis; treatment; non-invasive therapies; surgery; neurophisiology; imaging; motion analysis; personalized medicine

(This special issue belongs to the Section Orthopedics)

Oral Surgery: Recent Advances and Future Perspectives

edited by

Carlo Barausse

and

Gerardo Pellegrino

submission deadline 22 Dec 2025 | 1 articles | Viewed by 2893 | Submission Open

Keywords: oral surgery; implant dentistry; atrophic jaws; bone regeneration; digital dentistry

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Ablation, Embolization, and Stenting: Current Trends in Interventional Radiology

edited by Praveen Peddu

submission deadline 22 Dec 2025 | 1 articles | Viewed by 457 | Submission Open

Keywords: interventional radiology; ablation; embolization; stenting; minimally invasive therapy

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Displaying special issue 251-300 on page 6 of 31.

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