Dear Colleagues,

Various neoplastic and vascular pathologies can arise in the skull base, and such lesions are generally intractable due to the deep location and the proximity to critical neurovascular structures. Following decades of selfless effort by forerunners, we have observed many developments in open skull base surgical approaches in the late twentieth century. Excellent long-term outcomes have become more and more achievable thanks to an improved understanding of skull base anatomies, modern vascular and skull base reconstruction techniques, endovascular treatment, and stereotactic radiosurgery used either adjunctively or solely. Furthermore, endoscopic and exoscopic surgeries have taken a leading role in some skull base surgeries. With these multi-disciplinary therapeutic options, the paradigm has now begun to shift from “destructive” toward “minimally invasive,” aiming not only to “control lesions” but also to “preserve function”. In this Special Issue, a diversity of contributions from not only neurosurgeons but also otorhinolaryngologists, plastic surgeons, radiation oncologists, and endovascular surgeons are welcomed.

Prof. Dr. Soichi Oya
Dr. Hirotaka Hasegawa
Guest Editors

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• skull base surgery
• microsurgery
• endoscope
• exoscope
• cerebrovascular disease
• skull base reconstruction
• function-al preservation
• transsphenoidal surgery