Dear Colleagues,

Aortic dissection is characterized by an acute event with an intimal tear, with bleeding separating the layers of the aortic wall. These events result in blood flow in both lumina, called the false (newly developed) and true (existing) lumen, and potentially life-threatening disease. In type B aortic dissection, the primary entry tear is distal to the left subclavian artery. Depending on the development of the false lumen and the backflow of the blood via re-entry tears, normal perfusion, malperfusion of the visceral, spinal or peripheral vessels, or rupture can occur.

Standard therapy is still best medical treatment, alongisde the control of hypertension. The failure rate in the first 5 years is high, with a significant percentage of patients requiring invasive treatment. The current trend is pointing towards earlier and more invasive therapy. The most appropriate therapy and the optimal timepoint of intervention are still under debate. Lifelong surveillance and recurrent interventions/operations are necessary.

This Special Issue will address the following points:

• Pathophysiology of aortic dissection;
• Conservative treatment and outcomes;
• Intraoperative diagnostics;
• Outcome of stentgraft treatment;
• Complications of conservative treatment;
• Complications of invasive treatment;
• Indications for open treatment;
• Influence of risk factors on outcome or the progression of aortic dissection;
• Long-term surveillance;
• Novel therapeutic approaches.

Original clinical and basic science papers are welcome, as are reviews of special aspects of diagnostic findings or treatments.

Prof. Dr. Alexander Oberhuber
Prof. Dr. Hubert Schelzig
Prof. Dr. Bernhard Dorweiler
Guest Editors

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• aortic dissection
• stentgraft
• best medical treatment
• entry tear

• Influence of intensive care unit treatment on outcome of acute type B aortic dissection
• Vascular endothelial cadherines in the pathophysiology of onset of acute aortic dissection
• Incidence of stentgraft induced new entries after invasive treatment of aortic dissection
• Risk factors of rapid progress of acute type B aortic dissection
• Blood parameters contribute to false lumen thrombosis in type B aortic dissections post TEVAR
• TEVAR following ascending aortic repair or total arch repair for type A aortic dissection
• Endovascular treatment of chronic aortic dissection with fenestrated / branched stentgrafts - a meta-analysis
• Feasibility of total endovascular repair for patients with type A aortic dissection