Special Issue "Type B Aortic Dissection"

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Vascular Medicine".

Deadline for manuscript submissions: 25 September 2023 | Viewed by 494

Special Issue Editors

Department of Vascular and Endovascular Surgery, University Hospital Muenster, Muenster, Germany
Interests: aorta; stentgraft; dissection; endovascular; aneurysm; diabetic foot; peripheral occlusive disease
Clinic of Vascular and Endovascular Surgery, Heinrich -Heine-University Duesseldorf, Duesseldorf, Germany
Interests: vascular surgery; aorta; vascular biobanking; peripheral arterial disease; thoracic aorta; wound-healing; thrombocytes in vascular disease
Prof. Dr. Bernhard Dorweiler
E-Mail Website
Guest Editor
Department of Vascular and Endovascular Surgery, University Hospital Cologne, Cologne, Germany
Interests: thoracic aorta; computer assisted tomography; dissecting aneurysm

Special Issue Information

Dear Colleagues,

Aortic dissection is characterized by an acute event with an intimal tear, with bleeding separating the layers of the aortic wall. These events result in blood flow in both lumina, called the false (newly developed) and true (existing) lumen, and potentially life-threatening disease. In type B aortic dissection, the primary entry tear is distal to the left subclavian artery. Depending on the development of the false lumen and the backflow of the blood via re-entry tears, normal perfusion, malperfusion of the visceral, spinal or peripheral vessels, or rupture can occur.

Standard therapy is still best medical treatment, alongisde the control of hypertension. The failure rate in the first 5 years is high, with a significant percentage of patients requiring invasive treatment. The current trend is pointing towards earlier and more invasive therapy. The most appropriate therapy and the optimal timepoint of intervention are still under debate. Lifelong surveillance and recurrent interventions/operations are necessary.

This Special Issue will address the following points:

  • Pathophysiology of aortic dissection;
  • Conservative treatment and outcomes;
  • Intraoperative diagnostics;
  • Outcome of stentgraft treatment;
  • Complications of conservative treatment;
  • Complications of invasive treatment;
  • Indications for open treatment;
  • Influence of risk factors on outcome or the progression of aortic dissection;
  • Long-term surveillance;
  • Novel therapeutic approaches.

Original clinical and basic science papers are welcome, as are reviews of special aspects of diagnostic findings or treatments.

Prof. Dr. Alexander Oberhuber
Prof. Dr. Hubert Schelzig
Prof. Dr. Bernhard Dorweiler
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • aortic dissection
  • stentgraft
  • best medical treatment
  • entry tear

Published Papers (1 paper)

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Reintervention after Thoracic Endovascular Aortic Repair of Uncomplicated Type B Aortic Dissection
J. Clin. Med. 2023, 12(4), 1418; https://doi.org/10.3390/jcm12041418 - 10 Feb 2023
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Background: Data are scarce regarding the incidence, reasons, potential risk factors, and long-term outcomes of reintervention after thoracic endovascular aortic repair (TEVAR) in patients with uncomplicated type B aortic dissection (TBAD). Methods: Between January 2010 and December 2020, 238 patients with uncomplicated TBAD [...] Read more.
Background: Data are scarce regarding the incidence, reasons, potential risk factors, and long-term outcomes of reintervention after thoracic endovascular aortic repair (TEVAR) in patients with uncomplicated type B aortic dissection (TBAD). Methods: Between January 2010 and December 2020, 238 patients with uncomplicated TBAD who received TEVAR were analyzed retrospectively. The clinical baseline data, aorta anatomy, dissection characteristics, and details of the TEVAR procedure were evaluated and compared. A competing-risk regression model was used to estimate the cumulative incidences of reintervention. The multivariate Cox model was used to identify the independent risk factors. Results: The mean follow-up time was 68.6 months. A total of 27 (11.3%) cases of reintervention were observed. The competing-risk analyses showed that the 1-, 3-, and 5-year cumulative incidences of reintervention were 5.07%, 7.08%, and 14.0%, respectively. Reasons for reintervention included endoleak (25.9%), aneurysmal dilation (22.2%), retrograde type A aortic dissection (18.5%), distal stent-graft-induced new entry and false lumen expansion (18.5%), and dissection progression and/or malperfusion (14.8%). Multivariable Cox analysis demonstrated that a larger initial maximal aortic diameter (Hazard ratio [HR], 1.75; 95% Confidence interval [CI], 1.13–2.69, p = 0.011) and increased proximal landing zone oversizing (HR, 1.07; 95% CI, 1.01–1.47, p = 0.033) were the significant risk factors for reintervention. Long-term survival rates were comparable between patients with or without reintervention (p = 0.915). Conclusions: Reintervention after TEVAR in patients with uncomplicated TBAD is not uncommon. A larger initial maximal aortic diameter and excessive proximal landing zone oversizing are associated with the second intervention. Reintervention does not significantly affect long-term survival. Full article
(This article belongs to the Special Issue Type B Aortic Dissection)
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

  • Influence of intensive care unit treatment on outcome of acute type B aortic dissection
  • Vascular endothelial cadherines in the pathophysiology of onset of acute aortic dissection
  • Incidence of stentgraft induced new entries after invasive treatment of aortic dissection
  • Risk factors of rapid progress of acute type B aortic dissection
  • Blood parameters contribute to false lumen thrombosis in type B aortic dissections post TEVAR
  • TEVAR following ascending aortic repair or total arch repair for type A aortic dissection
  • Endovascular treatment of chronic aortic dissection with fenestrated / branched stentgrafts - a meta-analysis
  • Feasibility of total endovascular repair for patients with type A aortic dissection
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