Special Issue "Application of Dynamic MRI in Clinical Practice"

Dear Colleagues,

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a non-invasive imaging technique that can be used to study the microcirculatory system in vivo through tracking the diffusion of paramagnetic contrast agents over time and provides information on both anatomy and function. DCE-MRI has been widely investigated in perfusion-related research fields covering the central nervous system, cardiovascular system, respiratory system, digestive system,  genitourinary system, etc., and diseases focused on tumors, inflammation, hepatic fibrosis, cardiomyopathy and nephropathy, etc. The major clinical applications range from diagnosis/differential diagnosis to biological behavior assessment, risk stratification, classification and staging, organ function assessment, treatment response evaluation, and prognosis prediction, which have been providing more and more information for clinical practice.

However, there are still challenges and issues that need to be further studied and clarified during clinical practice, such as the lack of multi-center large-sample studies and, thereafter, the absence of high-level evidence, QA and QC for acquisition protocols in different centers, the robustness and repeatability of the parameters and interpretation of results, etc.

In this Special Issue, we welcome the submission of original research and review articles aiming to highlight the clinical potential of DCE-MRI and provide an overview of possible applications in diagnosis and treatment evaluation, raising awareness among clinicians of a promising non-invasive functional MRI tool that, after long being used for research, is now ready to enter the clinics.

Prof. Dr. Lei Tang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• magnetic resonance imaging
• dynamic contrast enhanced
• neoplasms
• diagnosis, differential
• biological behavior
• risk stratification
• classification/staging
• function assessment
• therapeutics response
• prognosis