Special Issue "Direct Oral Anticoagulants for Arterial or Venous Thromboembolic Events"

Dear Colleagues,

Venous thromboembolism (VTE) and arterial thromboembolism (ATE) are usually considered two distinct entities. However, growing evidence indicates a pathophysiologic linkage between them, as atherosclerotic and venous thrombotic events share several risk factors. Vascular adverse events (VAEs) are triggered by biological stimuli that activate coagulation and inflammatory pathways in both arterial and venous systems. Particularly, thrombin generation results in fibrin formation and platelet activation and aggregation in both ATE and VTE. In recent years, several data have emphasized pharmacologic strategies for the prevention of VAEs. This Special Issue of the Journal of Clinical Medicine focuses on the role of direct oral anticoagulants (DOACs) in the primary or secondary prevention of VTE or ATE.

Dr. Luca Costanzo
Guest Editor

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• direct oral anticoagulants
• dual pathway inhibition
• venous thromboembolism
• arterial thromboembolism
• platelets